St. Charles, MO

Travel Guide

A bridge over a calm river with a sunset sky.
A nighttime street scene with historic buildings, parked cars, and trees lining the road.
A historic brick street lined with vintage buildings, a red car parked on the side, and a yellow fire hydrant.
A cobblestone street lined with historic brick buildings, a large tree, and a white picket fence.
A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

Where to stay in St. Charles

Find the best St. Charles areas and neighborhoods for the activities you enjoy most. Learn more about St. Charles
Learn more about St. Charles

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
The price is ¥25,164 per night from Dec 16 to Dec 17
¥25,164
¥32,056 total
Dec 16 - Dec 17
includes taxes & fees
Book a stay at this luxury hotel in St. Charles. Enjoy a full-service spa, 6 restaurants, and a casino. Our guests praise the clean rooms in our reviews. Popular ...
Ameristar Casino Resort and Spa
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
3720 W Clay St St. Charles MO
The price is ¥18,028 per night from Dec 13 to Dec 14
¥18,028
¥20,721 total
Dec 13 - Dec 14
includes taxes & fees
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Hampton Inn St. Charles St. Peters
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
The price is ¥20,444 per night from Dec 13 to Dec 14
¥20,444
¥23,498 total
Dec 13 - Dec 14
includes taxes & fees
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Country Inn & Suites by Radisson, St. Charles Historic District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups

St. Charles MO
Book a stay at this family-friendly vacation home in St. Charles. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Ameristar Casino ...
10/10 Exceptional! (148 reviews)
"Great location, cool old house. There are quite a few steps to be aware of if you have trouble with them."

Reviewed on Oct 21, 2026

The St. Charles Guest House, lovely historic home, fun for families and groups
St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!

St Charles MO
Stay at this vacation home in St. Charles. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ameristar Casino St. Charles and Hollywood ...
9.8/10 Exceptional! (171 reviews)
"We had a nice stay in St. Charles at this property. Everything was clean, check in was smooth, and Rachel replied quickly to any questions we had. Property was a short walk to Main St. where there was a lot to see or grab a bite to eat. We loved the area and enjoyed our time there. Only negative ..."

Reviewed on Oct 26, 2026

St. Charles 1860's Gem - Sleeps 6!
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

Saint Charles MO
Stay at this vacation home in St. Charles. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ameristar Casino St. Charles and Hollywood ...
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular St. Charles attractions

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