Find Boutique Hotels in Clayton, MO

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Check availability on Clayton Boutique Hotels

Our top choices for Clayton boutique hotels

Front of property
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very Good, (577)
"Love this place."
United States
Robert
The price is ￥18,970
￥23,618 total
includes taxes & fees
Dec 19 - Dec 20
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Property amenity
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1912)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
The price is ￥17,742
￥21,101 total
includes taxes & fees
Dec 13 - Dec 14
Moonrise Hotel
Gastropub
The Cheshire

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1003)
"Excellent place to stay. "
United States
Todd
The price is ￥19,747
￥23,446 total
includes taxes & fees
Dec 17 - Dec 18
The Cheshire
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Clayton Hotel Reviews

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

10/10 Excellent
"Clean, nice staff, hot breakfast with variety of options"
Tamara 2-night trip
Posted 4 days ago
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

10/10 Excellent
"Excellent service "
Blessing 1-night trip
Posted 2 months ago
Le Méridien St. Louis Clayton

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Frequently asked questions

What's the best boutique accommodation in Clayton?
Seven Gables, St. Louis West, a Tribute Portfolio Hotel is a favorite hotel with our travelers looking for a stylish accommodation, and features 32 guestrooms, a garden, and free WiFi.
What's there to see and do in Clayton?
The shopping, restaurants, and sporting events are just some of the things to enjoy while you're in the area. Activities and attractions to experience around Clayton include St. Louis Union Station, Gateway Arch, and Chapel of St. Timothy And St. Titus, Concordia Seminary. You might also want to consider exploring Saint Louis Galleria Mall, St. Louis Art Museum, and St. Louis Zoo while you're here.
What's the best way to get to my boutique hotel in Clayton?
You have a few options for traveling to and around Clayton. The closest major airport is St. Louis Lambert Intl. Airport (STL), which is located 7.3 mi (11.7 km) away, but St. Louis, MO (SUS-Spirit of St. Louis) may also be an option. Make your way to Clayton Station to catch metro.