Brentwood Vacation Rentals

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Check prices for these dates

Tonight
Dec 10 - Dec 11
Tomorrow
Dec 11 - Dec 12
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Our top choices for Brentwood vacation rentals

Comfort Apartment | Individually decorated, individually furnished, desk, laptop workspace
White House at Grand Central

White House at Grand Central

White House at Grand Central
4.0 star property
Grand Center
8.6 out of 10, Excellent, (124)
"Very clean and very friendly people "
United States
Mary
The price is ￥10,718
￥22,552 total
includes taxes & fees
Jan 6 - Jan 7, 2026
White House at Grand Central
Outdoor dining
The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups
St. Charles Historic District
10.0 out of 10, Exceptional, (136)
"We loved staying here in this adorable clean house that was only 1 block off of downtown Main Street shopping. "
United States
Lisa S.
The St. Charles Guest House, lovely historic home, fun for families and groups
Studio Suite, 1 King Bed | Desk, laptop workspace, blackout drapes, WiFi
Value Suites Extended Stay - St Louis

Value Suites Extended Stay - St Louis

Value Suites Extended Stay - St Louis
3.0 star property
Maryland Heights
7.0 out of 10, Good, (1110)
"We’ve stayed here twice before and have always been pleased with everything. Very good hotel close to what we need."
United States
Timothy
The price is ￥54,726
￥76,332 total
includes taxes & fees
Dec 18 - Dec 19
Value Suites Extended Stay - St Louis
Fridge, microwave, oven, stovetop
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
The Hill
9.8 out of 10, Exceptional, (160)
"Very clean, check in was easy, great neighborhood with lots of food close. "
United States
Laura H.
The price is ￥11,997
￥21,042 total
includes taxes & fees
Dec 14 - Dec 15
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
Microwave, oven, stovetop, dishwasher
Stunning 1890's Home - Sleeps 8!

Stunning 1890's Home - Sleeps 8!

Stunning 1890's Home - Sleeps 8!
St. Charles Historic District
10.0 out of 10, Exceptional, (100)
"Check-in was easy and the house was lovely "
United States
Delfino A.
The price is ￥22,425
￥53,342 total
includes taxes & fees
Dec 23 - Dec 24
Stunning 1890's Home - Sleeps 8!
Microwave, oven, stovetop, dishwasher
Stylish City Reno Retreat!

Stylish City Reno Retreat!

Stylish City Reno Retreat!
Hyde Park
6.4 out of 10, (15)
"We were pleased with our stay and would stay again"
United States
Nicole L.
Stylish City Reno Retreat!
Interior
Luxury 2BEDROOM LOFT near Bush Stadium

Luxury 2BEDROOM LOFT near Bush Stadium

Luxury 2BEDROOM LOFT near Bush Stadium
Downtown St. Louis
9.4 out of 10, Exceptional, (6)
"The location was perfect to access all things Downtown! The space was clean and well furnished. Check in/out was a breeze and the included parking spot was a huge plus for us! Great place to stay! "
United States
Kelci Y.
Luxury 2BEDROOM LOFT near Bush Stadium
Outdoor dining
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
St. Charles Historic District
10.0 out of 10, Exceptional, (210)
"Nice view of the Mississippi in the morning. Just off of the main street in old town St Charles, this place was perfect for our needs."
United States
Ralph
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
Smart TV
Cozy Clark Suite in Frenchtown Saint Charles

Cozy Clark Suite in Frenchtown Saint Charles

Cozy Clark Suite in Frenchtown Saint Charles
St. Charles Historic District
9.6 out of 10, Exceptional, (14)
"Awesome place to stay"
United States
paul
The price is ￥10,585
￥38,499 total
includes taxes & fees
Dec 11 - Dec 12
Cozy Clark Suite in Frenchtown Saint Charles
Fridge, microwave, oven, stovetop
St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (134)
"This was such a cute historical home and was perfect for our weekend in St Charles!"
United States
Isabelle C.
The price is ￥20,562
￥40,792 total
includes taxes & fees
Jan 1 - Jan 2, 2026
St. Charles 1860's Gem - Sleeps 6!
Outdoor dining
Honky Tonk Hideaway

Honky Tonk Hideaway

Honky Tonk Hideaway
St. Charles Historic District
8.8 out of 10, Excellent, (12)
"Great location close to historic district."
United States
Hugh S.
The price is ￥14,114
￥46,152 total
includes taxes & fees
Dec 11 - Dec 12
Honky Tonk Hideaway
Fridge, microwave, oven, stovetop
Home Near Main Street-Covered Patio-Hot Tub!

Home Near Main Street-Covered Patio-Hot Tub!

Home Near Main Street-Covered Patio-Hot Tub!
Saint Charles
9.8 out of 10, Exceptional, (26)
"The place was great! "
United States
Melissa I.
The price is ￥30,188
￥70,903 total
includes taxes & fees
Dec 11 - Dec 12
Home Near Main Street-Covered Patio-Hot Tub!
2 bedrooms, desk, iron/ironing board, travel crib
Madison House 1 -Walk to Main St

Madison House 1 -Walk to Main St

Madison House 1 -Walk to Main St
St. Charles Historic District
8.6 out of 10, Excellent, (14)
"The house was clean and well stocked, location was great, and plenty of street parking. "
United States
Brad K.
The price is ￥13,957
￥37,552 total
includes taxes & fees
Dec 14 - Dec 15
Madison House 1 -Walk to Main St
Dining
Tamm Ave 3-BR Retreat

Tamm Ave 3-BR Retreat

Tamm Ave 3-BR Retreat
Dogtown
9.6 out of 10, Exceptional, (48)
"The host was amazing with communication and checking in on how things were going. Property is in a good location and not too far from major attractions. Street of residence is a pretty narrow two way street so vehicles larger than a sedan may have some challenges coming and going. Overall a nice, quiet place to stay!"
United States
Yashika T.
Tamm Ave 3-BR Retreat
Fridge, microwave, oven, coffee/tea maker
Stylish South City King 1BR Apt

Stylish South City King 1BR Apt

Stylish South City King 1BR Apt
2.0 star property
Marine Villa
10.0 out of 10, Exceptional, (9)
"Great location, great accommodations, great host."
United States
Scott W.
The price is ￥12,546
￥27,999 total
includes taxes & fees
Dec 11 - Dec 12
Stylish South City King 1BR Apt
Interior
Residence on the Roundabout

Residence on the Roundabout

Residence on the Roundabout
St Charles
9.4 out of 10, Exceptional, (144)
"House was very nice. Pictures were good and we knew what to expect. Location was great for where we wanted to go.Owner was punctual when we had any questions!"
United States
Anne L.
Residence on the Roundabout
Fridge, microwave, oven, stovetop
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
St. Charles Historic District
9.8 out of 10, Exceptional, (61)
"We had a great weekend and enjoyed the house very much! We had everything we needed!"
United States
Laurie S.
The price is ￥25,875
￥65,903 total
includes taxes & fees
Dec 11 - Dec 12
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
2 bedrooms, desk, iron/ironing board, free WiFi
The Otter Suite at Divine Otter

The Otter Suite at Divine Otter

The Otter Suite at Divine Otter
St. Charles Historic District
9.0 out of 10, Wonderful, (7)
"We absolutely loved this place! I would recommend this place. We had one issue but it was resolved. If you have children, I would probably stay somewhere else. There are bars all around and gets loud at night but it does get really quiet after 1:30 a.m. The property manager was absolutely amazing and is very quick to respond to your needs. "
United States
kim F.
The Otter Suite at Divine Otter
Terrace/patio
Brand New! Soulard Charmer - Pet Friendly.

Brand New! Soulard Charmer - Pet Friendly.

Brand New! Soulard Charmer - Pet Friendly.
Soulard
9.6 out of 10, Exceptional, (24)
"This house was beautiful and in a very nice spot in St. Louis. Close to everything and the hosts were amazing. Would definitely use again "
United States
Justin B.
The price is ￥20,465
￥40,852 total
includes taxes & fees
Dec 11 - Dec 12
Brand New! Soulard Charmer - Pet Friendly.
Outdoor dining
Spacious 2 BR Balcony Hideaway

Spacious 2 BR Balcony Hideaway

Spacious 2 BR Balcony Hideaway
Northampton
8.0 out of 10, Very Good, (15)
"Great stay! Management was easy to reach and very helpful when we couldnt find the correct wifi network. Nice place, would stay again."
United States
Bob C.
Spacious 2 BR Balcony Hideaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Brentwood Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Clean room, good breakfast and good location "
Martin 2-night trip
Posted 1 day ago
Clayton Plaza Hotel & Extended Stay

Find out more about Brentwood

Search for holiday rentals in Brentwood on Expedia! You can easily find your home rentals, villas, holiday apartments in Brentwood using one of the methods below:

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Look no further and take a look at our great range of rental properties in Brentwood!

Frequently asked questions

Are there vacation rentals in Brentwood?

Yes, we offer vacation rentals close to the most popular points of interest in Brentwood, or you can choose a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in Brentwood. Allow some time to check out the zoo during your trip.

What's the top vacation rental in Brentwood?

Stunning 1890's Home - Sleeps 8! : This vacation home rental near Brentwood is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 4 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Brentwood?

Explore the area and family-friendly sights such as St. Louis Zoo, or get out into nature at a spot like Lindenwood Park. You’ll find favorite places to visit like St. Louis Union Station and Gateway Arch in the larger area.

What’s a vacation rental in Brentwood like?

Vacation rentals are privately owned properties you can book for short or long periods in Brentwood. Vacation rentals offer amenities such as laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, vacation rentals can offer a sense of security away from shared hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for family gatherings.