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Find hotels in Downtown Clayton, St. Louis from ¥8,897

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Discover 1,702 Downtown Clayton hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2932)
"Great property, delicious breakfast, superb service. "
The price is ¥15,406
¥17,946 total
includes taxes & fees
Aug 3 - Aug 4
Clayton Plaza Hotel & Extended Stay

AC Hotel St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (101)
"Great, clean hotel "
The price is ¥19,756
¥23,013 total
includes taxes & fees
Aug 3 - Aug 4
AC Hotel St. Louis Clayton

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (538)
"Wish they still had a pool"
The price is ¥85,362
¥99,437 total
includes taxes & fees
Jul 20 - Jul 21
The Ritz-Carlton, St. Louis

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (628)
"Great stay, friendly staff, great location! I highly recommend "
The price is ¥25,635
¥30,118 total
includes taxes & fees
Aug 3 - Aug 4
Le Méridien St. Louis Clayton

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property
8.4 out of 10, Very Good, (565)
"Fantastic property in Old St Louis. Walkable village feeling with cafes, bakery & Vintage/Antique Watch Shop next door. :15 min drive from the airport with huge high tech rooms."
The price is ¥17,986
¥21,387 total
includes taxes & fees
Jul 27 - Jul 28
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Drury Plaza Hotel St. Louis Chesterfield

3.0 star property
9.6 out of 10, Exceptional, (1012)
"Great place!"
The price is ¥19,164
¥22,228 total
includes taxes & fees
Jul 20 - Jul 21
Drury Plaza Hotel St. Louis Chesterfield

River City Casino & Hotel

4.0 star property
9.0 out of 10, Wonderful, (1274)
"It was an excellent stay "
River City Casino & Hotel

The Knight Center at Washington University

2.5 star property
9.4 out of 10, Exceptional, (342)
"Very nice place to stay and stuff was great "
The price is ¥26,405
¥30,362 total
includes taxes & fees
Jul 29 - Jul 30
The Knight Center at Washington University

Hyatt Place St. Louis/Chesterfield

3.0 star property
9.6 out of 10, Exceptional, (1011)
"Excellent hotel "
The price is ¥19,107
¥22,162 total
includes taxes & fees
Jul 21 - Jul 22
Hyatt Place St. Louis/Chesterfield

Hollywood Casino & Hotel St. Louis

3.5 star property
8.4 out of 10, Very Good, (1969)
"This my favorite hotel to getaway in "
The price is ¥18,796
¥24,080 total
includes taxes & fees
Jul 31 - Aug 1
Hollywood Casino & Hotel St. Louis

Best Western Plus Pontoon Beach

3.0 star property
8.6 out of 10, Excellent, (695)
"Nice overnight stay"
The price is ¥13,931
¥15,460 total
includes taxes & fees
Jul 27 - Jul 28
Best Western Plus Pontoon Beach

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1543)
"Great location for our stay"
The Wildwood Hotel

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1003)
"I love staying at the Ameristar on my visits to STL. The rooms are so spacious and luxurious. "
The price is ¥27,444
¥34,521 total
includes taxes & fees
Jul 17 - Jul 18
Ameristar Casino Resort and Spa

Pear Tree Inn St. Louis Convention Center

3.0 star property
8.8 out of 10, Excellent, (1006)
"Overall great location and place to stay for the price "
The price is ¥13,415
¥15,684 total
includes taxes & fees
Aug 6 - Aug 7
Pear Tree Inn St. Louis Convention Center

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4.0 star property
8.8 out of 10, Excellent, (1021)
"Fun stay in a cool hotel. Loved the twin bed bunk room. Beds weee amazing "
The price is ¥19,925
¥23,497 total
includes taxes & fees
Jul 20 - Jul 21
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Drury Plaza Hotel St. Louis Creve Coeur

3.0 star property
9.2 out of 10, Wonderful, (1002)
"We really enjoyed our stay and will stay there again if needed. "
The price is ¥18,169
¥21,119 total
includes taxes & fees
Jul 20 - Jul 21
Drury Plaza Hotel St. Louis Creve Coeur

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1007)
"Very Nice area with lots of shops and restaurants, clean comfortable rooms with very friendly staff, and good morning breakfast. "
The price is ¥16,792
¥19,299 total
includes taxes & fees
Jul 20 - Jul 21
Country Inn & Suites by Radisson, St. Charles Historic District

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (2852)
"Great place to stay"
The price is ¥20,639
¥24,133 total
includes taxes & fees
Jul 20 - Jul 21
Drury Plaza Hotel St. Louis at the Arch

Drury Inn & Suites St. Louis Airport

3.0 star property
9.2 out of 10, Wonderful, (1016)
"Such an amazing place to stay if you need the airport - they dropped me off and picked me up - it was so simple! "
The price is ¥16,363
¥19,200 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites St. Louis Airport

Comfort Inn St. Louis Airport

3.0 star property
8.4 out of 10, Very Good, (873)
"This hotel was excellent. Would definitely stay here again!"
The price is ¥13,269
¥15,865 total
includes taxes & fees
Jul 20 - Jul 21
Comfort Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most.
Downtown St. Louis map

Downtown St. Louis

3 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Clayton map

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End map

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur map

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Downtown West map

Downtown West

3 out of top 10 points of interest in this area

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Frequently asked questions

What's it like in Downtown Clayton?

Travelers to the Downtown Clayton neighborhood in St. Louis will be sure to enjoy their stay.

What's a favorite place to stay in Downtown Clayton?

Based on Expedia customer reviews, The Ritz-Carlton, St. Louis is the highest ranked property in Downtown Clayton. This hotel offers a restaurant and a fitness center. Other favorite options in the area include Le Méridien St. Louis Clayton and AC Hotel St. Louis Clayton.

How many hotels should I expect to find in the Downtown Clayton area?

Expedia has 6 Downtown Clayton hotels and other accommodations, and one might make a good home base for venturing out into the greater St. Louis area.

If I need to cancel my hotel reservation in Downtown Clayton, will I receive a refund?

Yes! Most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can use the "fully refundable" filter to view top deals in Downtown Clayton.

Where can I learn more about changing or cancelling my trip to Downtown Clayton?

For more details about rescheduling or cancelling your trip to Downtown Clayton, go to https://www.expedia.com/service/.

What can I see and do in this St. Louis neighborhood?

St. Louis Zoo, Shaw Park Tennis Center, and Saint Louis Galleria Mall are just a few of the places to visit in and around Downtown Clayton. While you're out sightseeing, Tao Tennis Center and Center of Creative Arts are a couple of additional sights to visit in St. Louis.

How can I get around Downtown Clayton and the greater St. Louis area?

Ready to get out and explore the city? Clayton Station is the closest metro station.