A large white building with a dome and a statue in front, surrounded by fountains and trees.

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Check availability on St. Louis Luxury Hotels

Tonight
Oct 8 - Oct 9
Tomorrow
Oct 9 - Oct 10
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for St. Louis luxury hotels

A modern hotel lobby with a glass facade, seating area, and a staircase.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A couple relaxing by a window overlooking a bridge and water.

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
￥59,250
￥69,280 total
includes taxes & fees
Oct 14 - Oct 15
Four Seasons Hotel St Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

2. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
￥25,467
￥34,697 total
includes taxes & fees
Nov 1 - Nov 2
The Royal Sonesta Chase Park Plaza St. Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

3. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
￥26,726
￥33,857 total
includes taxes & fees
Oct 12 - Oct 13
Ameristar Casino Resort and Spa
An indoor swimming pool with a 'SWIM FOR LIFE' sign, surrounded by patterned walls and windows.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this downtown St. Louis hotel with spa services and indoor pool.
￥22,723
￥27,361 total
includes taxes & fees
Nov 1 - Nov 2
21C Museum Hotel St Louis
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
A restaurant with a central bar area, seating arrangements, and a fireplace.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.
A modern building with a unique, curved roof structure.

5. The Cheshire

The Cheshire
Richmond Heights
￥23,475
￥27,874 total
includes taxes & fees
Oct 25 - Oct 26
The Cheshire
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.
A spa bath with a sign indicating a capacity of 8 persons.

6. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
￥21,036
￥24,978 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood
A hotel room with a sofa, armchair, coffee table, TV, and artwork on the wall.
An indoor tennis court with multiple courts, a net, and players.
A hotel room with orange furniture, a glass coffee table, a dining area with a table and chairs, and a patterned carpet.
A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.

7. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
  • Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
￥21,896
￥25,397 total
includes taxes & fees
Oct 30 - Oct 31
DoubleTree by Hilton Hotel St. Louis - Chesterfield
A bar area with wooden tables, leather seating, and a bar counter.
A covered outdoor area with two tables and two chairs, a white railing, and a view of a road and trees.
A hotel room with a bed, bedside table, lamp, chair, desk, microwave, refrigerator, and a door.
A large white building with a central tower, a parking lot, and a tree with red leaves.

8. The Inn at Elijah McLeans

The Inn at Elijah McLeans
Washington
￥19,994
￥22,763 total
includes taxes & fees
Oct 11 - Oct 12
The Inn at Elijah McLeans
View all properties

Top St. Louis Hotel Reviews

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Helped by letting us leave our car in lot after we checked out. Great food for free breakfast."
Barbara 2-night trip
Posted 9 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"sorry to see the bar is closed"
DENNIS 3-night trip
Posted 15 hours ago
Pear Tree Inn St. Louis Near Union Station

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to St. Louis?
Travel to St. Louis Lambert Intl. Airport (STL) Airport or Belleville, IL (BLV-MidAmerica-St. Louis) Airport, and then treat yourself to a stay at one of 8 St. Louis luxury hotels. Known for its art and theater, St. Louis also has some interesting things to see and do including St. Louis Union Station and St. Louis Zoo, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in St. Louis?
21C Museum Hotel St Louis is a luxury hotel with spa services and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. St. Louis Union Station Hotel, Curio Collection by Hilton and Ameristar Casino Resort and Spa are other upscale choices for your trip.
How many luxury hotels should I expect to find in St. Louis?
Lie in the lap of luxury during your getaway to St. Louis in one of Expedia's 8 luxury hotels.
When can I expect good weather in St. Louis?
Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for St. Louis is 54 inches.
What's there to see and do in St. Louis?
Take in some sights and attractions while you're in St. Louis by visiting St. Louis Union Station, St. Louis Zoo, and St. Louis Aquarium at Union Station. If you have extra time while you're in the area, you might want to see The St. Louis Wheel and Energizer Park.
How can I get around St. Louis?
It's easier to get around town comfortably when you know your options. Take advantage of metro transit at Stadium Station, 8th and Pine Station, and Convention Center Station.

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