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Our top choices for Midtown hotels

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (734 reviews)
"Clean room and spacious "
United States
Vivian
The price is ¥21,225
¥24,818 total
includes taxes & fees
May 21 - May 22
Element St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1,002 reviews)
"Great, convenient location. Rooms were nice and complimentary breakfast was great. "
United States
Marty
The price is ¥17,294
¥20,568 total
includes taxes & fees
May 21 - May 22
Residence Inn by Marriott St Louis Downtown

The Principal Hotel

The Principal Hotel
3.5 star property
21.4 km from Midtown
9.8 out of 10, Exceptional, (256 reviews)
"Location is great.Beds were very comfortable."
United States
Denise
The price is ¥15,254
¥16,928 total
includes taxes & fees
May 12 - May 13
The Principal Hotel

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (696 reviews)
"This place is independently owned and the owners show pride. The room and common areas were spotless. The breakfast had choices and was very good. The mattress must be new, it was the most comfortable mattress I’ve slept on. I will stay here again. "
United States
Eric
The price is ¥22,640
¥26,031 total
includes taxes & fees
May 7 - May 8
Country Hearth Inn & Suites Edwardsville St. Louis

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.0 out of 10, Wonderful, (1,542 reviews)
"Excellent place to stay with 6 restaurants to pickf from"
United States
Dennis
The price is ¥12,262
¥16,550 total
includes taxes & fees
Jun 3 - Jun 4
River City Casino & Hotel

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.2 km from Midtown
8.0 out of 10, Very Good, (1,256 reviews)
"Nice room, comfortable bed, good breakfast."
United States
John
The price is ¥14,077
¥16,258 total
includes taxes & fees
May 17 - May 18
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
29.2 km from Midtown
8.0 out of 10, Very Good, (1,005 reviews)
"The room was excellent"
United States
willie
The price is ¥11,359
¥12,606 total
includes taxes & fees
May 24 - May 25
Super 8 by Wyndham Troy IL/St. Louis Area

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
23.3 km from Midtown
7.8 out of 10, Good, (1,206 reviews)
"This place is always clean and staff is always friendly. I stay here we very week for work "
United States
Steve
The price is ¥13,364
¥15,434 total
includes taxes & fees
May 10 - May 11
Wingate by Wyndham St. Louis/Fenton Route 66

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
24.2 km from Midtown
8.4 out of 10, Very Good, (843 reviews)
"Very friendly staff, comfortable room and convenient location "
United States
Aimee
The price is ¥15,722
¥18,077 total
includes taxes & fees
May 26 - May 27
Comfort Inn Edwardsville - St. Louis

Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis
3.0 star property
24.3 km from Midtown
7.4 out of 10, Good, (1,004 reviews)
"Very good staff "
United States
Andrzej
The price is ¥11,180
¥12,855 total
includes taxes & fees
May 26 - May 27
Quality Inn O'Fallon IL - St. Louis

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
21.7 km from Midtown
9.2 out of 10, Wonderful, (279 reviews)
"Breakfast was good and the room was clean "
United States
jennifer
The price is ¥15,593
¥18,008 total
includes taxes & fees
May 31 - Jun 1
Best Western Plus Fenton

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
16 km from Midtown
9.2 out of 10, Wonderful, (1,011 reviews)
"Rooms were outstanding and breakfast was good"
United States
james
The price is ¥18,611
¥22,841 total
includes taxes & fees
Jun 2 - Jun 3
Hyatt Select St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
17.3 km from Midtown
9.4 out of 10, Exceptional, (2,975 reviews)
"Room was quiet, good breakfast, easy access to airport, also offer long term parking and airport shuttle."
United States
LeAndra
The price is ¥15,770
¥18,566 total
includes taxes & fees
May 10 - May 11
Pear Tree Inn St. Louis Airport

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
27.1 km from Midtown
8.6 out of 10, Excellent, (1,005 reviews)
"The room was very nice and clean. The bed was comfortable."
United States
Julia
The price is ¥25,030
¥31,862 total
includes taxes & fees
May 25 - May 26
Ameristar Casino Resort and Spa

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
25.8 km from Midtown
8.4 out of 10, Very Good, (2,199 reviews)
"Great stay. Great environment. Great staff."
United States
Eric
The price is ¥15,376
¥20,226 total
includes taxes & fees
Jun 1 - Jun 2
Hollywood Casino & Hotel St. Louis

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
25.8 km from Midtown
9.6 out of 10, Exceptional, (1,007 reviews)
"Very nice, well maintained hotel with generous size rooms and great amenities. "
United States
William
The price is ¥18,708
¥21,884 total
includes taxes & fees
May 24 - May 25
Drury Inn & Suites Southwest St. Louis

Best Western St. Louis Inn

Best Western St. Louis Inn
2.5 star property
22.7 km from Midtown
8.2 out of 10, Very Good, (1,009 reviews)
"Our room was clean and staff was super friendly!"
United States
Amber
The price is ¥10,995
¥12,642 total
includes taxes & fees
Jun 2 - Jun 3
Best Western St. Louis Inn

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.6 out of 10, Excellent, (4,053 reviews)
"Great location"
United States
Bruce
The price is ¥19,975
¥23,556 total
includes taxes & fees
May 25 - May 26
Hyatt Regency St. Louis at The Arch

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
27.6 km from Midtown
8.4 out of 10, Very Good, (1,006 reviews)
"The breakfast was good. They had two different waffle choices every day. "
United States
Josephine
The price is ¥15,601
¥17,931 total
includes taxes & fees
May 31 - Jun 1
Comfort Suites St Charles - St Louis

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.4 km from Midtown
9.4 out of 10, Exceptional, (766 reviews)
"Great place to stay and get good sleep and an excellent breakfast."
United States
debbie
The price is ¥18,866
¥20,938 total
includes taxes & fees
May 24 - May 25
Holiday Inn Express Troy by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on our traveler data, Residence Inn by Marriott St Louis Downtown is one of the top choices for your stay in Midtown. This hotel is a short 14-minute walk from St. Louis University, and it offers an indoor pool and in-room kitchens. Another good choice for your stay in the neighborhood is Element St. Louis Midtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.
Where can I learn more about changing or cancelling my trip to Midtown?
To access more information about picking new dates or cancelling your trip to Midtown, go to https://www.expedia.com/service/.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks like Washington Avenue Historic District, Scott Joplin House State Historic Site, and Samuel Cupples House and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighborhood. Favorite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium, and Gateway Arch. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

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