Lodging Image

Find hotels in Midtown, St. Louis

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown
8.8 out of 10, Excellent, (859 reviews)
"Would stay again!"
United States
Julie
The price is ¥22,595
¥26,420 total
includes taxes & fees
Nov 15 - Nov 16
Element by Marriott St. Louis Midtown

2. Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.6 out of 10, Good, (1,000 reviews)
"The room was very clean, with no normal hotel mildew smell. The lack of smell was amazing, actually. The staff was super helpful and parking was gated with plenty of spots. We’d definitely be back! Thank you Marriot."
United States
Kirsten
The price is ¥17,381
¥20,671 total
includes taxes & fees
Nov 22 - Nov 23
Residence Inn by Marriott St Louis Downtown

3. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
0.8 km from Midtown
8.8 out of 10, Excellent, (1,167 reviews)
"Loved the hotel!"
United States
Stephanie
The price is ¥16,329
¥19,256 total
includes taxes & fees
Nov 23 - Nov 24
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 1.3 km from Midtown
9.2 out of 10, Wonderful, (1,008 reviews)
"I would stay here again."
United States
Demarco
The price is ¥17,326
¥20,670 total
includes taxes & fees
Nov 22 - Nov 23
Fairfield Inn & Suites by Marriott St. Louis Downtown

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 2.1 km from Midtown
9.0 out of 10, Wonderful, (2,151 reviews)
"Wonderful Stay!"
United States
A.R.
The price is ¥22,700
¥27,333 total
includes taxes & fees
Dec 1 - Dec 2
21C Museum Hotel St Louis

6. Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 1.2 km from Midtown
8.8 out of 10, Excellent, (2,279 reviews)
"It was nice place to stay and the staff was great."
United States
Samuwel
The price is ¥16,431
¥19,212 total
includes taxes & fees
Nov 22 - Nov 23
Pear Tree Inn St. Louis Near Union Station

7. Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station
3.0 star property
Downtown West, 1.5 km from Midtown
9.4 out of 10, Exceptional, (1,622 reviews)
"Love staying here"
United States
gina
The price is ¥17,934
¥21,329 total
includes taxes & fees
Nov 29 - Nov 30
Drury Plaza Hotel St. Louis Union Station

8. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West, 1.7 km from Midtown
8.8 out of 10, Excellent, (1,004 reviews)
"Front desk staff was very helpful in answering question about the property and surrounding area!"
United States
William
The price is ¥24,488
¥29,123 total
includes taxes & fees
Nov 22 - Nov 23
St. Louis Union Station Hotel, Curio Collection by Hilton

9. Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate, 2 km from Midtown
8.2 out of 10, Very good, (435 reviews)
"I love the Comfort inn. So clean, so comfortable and staff is always nice."
United States
Michelle
The price is ¥17,134
¥20,035 total
includes taxes & fees
Dec 11 - Dec 12
Comfort Inn & Suites Saint Louis Lafayette Square

10. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 3 km from Midtown
9.4 out of 10, Exceptional, (1,367 reviews)
"Great place to stay."
United States
brandon
The price is ¥21,963
¥26,120 total
includes taxes & fees
Nov 22 - Nov 23
Live by Loews - St.Louis

11. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.6 out of 10, Excellent, (4,373 reviews)
"Great location and great place to visit"
United States
Tracy
The price is ¥17,776
¥20,964 total
includes taxes & fees
Nov 28 - Nov 29
Hyatt Regency St. Louis at The Arch

12. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 3 km from Midtown
8.6 out of 10, Excellent, (1,001 reviews)
"Very nice place to stay."
United States
Ruth
The price is ¥22,520
¥26,333 total
includes taxes & fees
Dec 7 - Dec 8
Home2 Suites by Hilton St. Louis/Forest Park

13. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
3.5 star property
Downtown St. Louis, 3.5 km from Midtown
8.8 out of 10, Excellent, (1,468 reviews)
"Would stay here again with my family"
United States
Andrew
The price is ¥16,714
¥19,544 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

14. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 2.2 km from Midtown
8.6 out of 10, Excellent, (1,007 reviews)
"Very nice staff and helped us with all our needs and was close to the event we were going to and loved the pool table and pool they had there"
United States
Brittany
The price is ¥17,997
¥21,044 total
includes taxes & fees
Nov 15 - Nov 16
Aloft by Marriott St Louis Central West End

15. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 3.1 km from Midtown
9.0 out of 10, Wonderful, (1,372 reviews)
"Loved our stay!"
United States
Megan
The price is ¥16,654
¥19,807 total
includes taxes & fees
Dec 10 - Dec 11
Embassy Suites by Hilton St. Louis Downtown

16. Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 2.5 km from Midtown
7.8 out of 10, Good, (1,019 reviews)
"Its a nice hotel with good breakfast"
United States
Arthur
The price is ¥11,685
¥13,663 total
includes taxes & fees
Dec 11 - Dec 12
Tru By Hilton St. Louis Downtown

17. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis, 2.9 km from Midtown
8.8 out of 10, Excellent, (1,004 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
The price is ¥19,328
¥22,600 total
includes taxes & fees
Nov 22 - Nov 23
The Westin St. Louis

18. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.6 out of 10, Exceptional, (3,839 reviews)
"Very nice hotel.. love that are arch is right behind it.."
United States
Nicole
The price is ¥22,752
¥26,604 total
includes taxes & fees
Nov 16 - Nov 17
Drury Plaza Hotel St. Louis at the Arch

19. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 3.6 km from Midtown
9.2 out of 10, Wonderful, (1,008 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
The price is ¥23,543
¥32,423 total
includes taxes & fees
Nov 22 - Nov 23
The Royal Sonesta Chase Park Plaza St. Louis

20. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 2.9 km from Midtown
9.0 out of 10, Wonderful, (1,013 reviews)
"Good for a quick stay a little pricey for what you get"
United States
Jackson
The price is ¥15,311
¥18,209 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard by Marriott St. Louis Downtown/Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Midtown

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
An outdoor patio area with seating, planters, and a grill.
Element by Marriott St. Louis Midtown
3.0 star property
8.8
Excellent
859 reviews
View
An outdoor patio area with seating, a fire pit, and a grill.
Residence Inn by Marriott St Louis Downtown
3.0 star property
7.6
Good
1,000 reviews
View
An indoor pool area with a hot tub, seating, and a stone wall.
Drury Plaza Hotel St. Louis Union Station
3.0 star property
9.4
Exceptional
1,622 reviews
View
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
8.8
Excellent
1,167 reviews
View
A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.
Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
9.2
Wonderful
1,008 reviews
View

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on our traveler data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 36 Midtown hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.
Where can I learn more about changing or cancelling my trip to Midtown?
To access more information about picking new dates or cancelling your trip to Midtown, go to https://www.expedia.com/service/.
What are the top things to see and do in Midtown?
Sights like Red Flag, Scott Joplin House State Historic Site, and Museum of Contemporary Religious Art can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighborhood. St. Louis Union Station, Hermann Stadium, and .ZACK Theater are just a few of the places to visit in and around Midtown. While you're out sightseeing, Fubar and The Sovereign - St. Louis are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

Explore a world of travel with Expedia