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Our top choices for Midtown hotels

Element St. Louis Midtown
Element St. Louis Midtown
Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Country Hearth Inn & Suites Edwardsville St. Louis
Country Hearth Inn & Suites Edwardsville St. Louis
Hampton Inn St. Louis - Columbia
Hampton Inn St. Louis - Columbia
Holiday Inn St. Louis Fairview Heights by IHG
Holiday Inn St. Louis Fairview Heights by IHG
Best Western Plus Fenton
Best Western Plus Fenton
The Principal Hotel
The Principal Hotel
Holiday Inn Express & Suites O'Fallon/Shiloh by IHG
Holiday Inn Express & Suites O'Fallon/Shiloh by IHG
Moonrise Hotel
Moonrise Hotel
River City Casino & Hotel
River City Casino & Hotel
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
Hampton Inn O'Fallon
Hampton Inn O'Fallon
Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites Southwest St. Louis
The Knight Center at Washington University
The Knight Center at Washington University
Hampton Inn & Suites St. Louis at Forest Park
Hampton Inn & Suites St. Louis at Forest Park
Best Western St. Louis-Kirkwood Route 66
Best Western St. Louis-Kirkwood Route 66
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
Holiday Inn Express & Suites Edwardsville by IHG
Holiday Inn Express & Suites Edwardsville by IHG
Hampton Inn By Hilton St Louis Airport
Hampton Inn By Hilton St Louis AirportWhere to stay in Midtown

Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Top Midtown Hotel Reviews

Clayton Plaza Hotel & Extended Stay
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