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Our top choices for Midtown hotels

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (682 reviews)
"Staff was amazing and hotel was super clean. Great locations with easy access. Valet was fast and took great care of us. "
United States
Kyle
The price is ¥21,067
¥24,633 total
includes taxes & fees
Mar 9 - Mar 10
Element St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1,005 reviews)
"Very nice hotel. Spacious room. Breakfast was wonderful!!"
United States
Jami
The price is ¥17,790
¥21,158 total
includes taxes & fees
Mar 29 - Mar 30
Residence Inn by Marriott St Louis Downtown

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.2 km from Midtown
8.0 out of 10, Very Good, (1,111 reviews)
"Great room, great people, great breakfast "
United States
Jaiden
The price is ¥13,927
¥16,085 total
includes taxes & fees
Mar 3 - Mar 4
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (671 reviews)
"Room was great,staff friendly! All together a great stay."
United States
Zachary
The price is ¥20,130
¥23,145 total
includes taxes & fees
Mar 3 - Mar 4
Country Hearth Inn & Suites Edwardsville St. Louis

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
21.2 km from Midtown
8.6 out of 10, Excellent, (491 reviews)
"Everything was clean, the staff was pleasant. I had a good stay."
United States
Elizabeth
The price is ¥17,343
¥19,247 total
includes taxes & fees
Mar 30 - Mar 31
Hampton Inn St. Louis - Columbia

Holiday Inn St. Louis Fairview Heights by IHG

Holiday Inn St. Louis Fairview Heights by IHG
3.0 star property
21.6 km from Midtown
8.6 out of 10, Excellent, (671 reviews)
"Great stay. "
United States
David
The price is ¥18,414
¥20,804 total
includes taxes & fees
Mar 5 - Mar 6
Holiday Inn St. Louis Fairview Heights by IHG

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
21.7 km from Midtown
9.2 out of 10, Wonderful, (219 reviews)
"Stay was great, and the pool was perfect for my daughter and her friend. Wonderful spot for an easy "stay cation" with the girls. "
United States
Melissa
The price is ¥15,480
¥17,877 total
includes taxes & fees
Mar 3 - Mar 4
Best Western Plus Fenton

The Principal Hotel

The Principal Hotel
3.5 star property
21.4 km from Midtown
9.8 out of 10, Exceptional, (207 reviews)
"Great stay and very clean!"
United States
David
The price is ¥17,604
¥19,537 total
includes taxes & fees
Mar 3 - Mar 4
The Principal Hotel

Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

Holiday Inn Express & Suites O'Fallon/Shiloh by IHG
2.5 star property
27.2 km from Midtown
8.4 out of 10, Very Good, (581 reviews)
"Great room and staff"
United States
Joseph
The price is ¥18,882
¥20,955 total
includes taxes & fees
Mar 25 - Mar 26
Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

Moonrise Hotel

Moonrise Hotel
4.0 star property
6.8 km from Midtown
9.0 out of 10, Wonderful, (1,920 reviews)
"The staff was wonderful. Very unique hotel it was awesome."
United States
Jaden
The price is ¥21,628
¥25,723 total
includes taxes & fees
Mar 4 - Mar 5
Moonrise Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.0 out of 10, Wonderful, (1,492 reviews)
"Clean and comfy great food "
United States
Theresa A
The price is ¥13,631
¥18,133 total
includes taxes & fees
Apr 2 - Apr 3
River City Casino & Hotel

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.4 out of 10, Exceptional, (3,342 reviews)
"Nice staff, clean rooms, dinner and breakfast for quests. "
United States
Brad
The price is ¥23,406
¥27,368 total
includes taxes & fees
Mar 3 - Mar 4
Drury Plaza Hotel St. Louis at the Arch

Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
26.3 km from Midtown
9.2 out of 10, Wonderful, (827 reviews)
"Breakfast was swell. Convenient parking, and friendly staff."
United States
Troylisa
The price is ¥17,787
¥20,629 total
includes taxes & fees
Mar 11 - Mar 12
Hampton Inn O'Fallon

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
25.8 km from Midtown
9.6 out of 10, Exceptional, (1,002 reviews)
"Great stay"
United States
Maureen
The price is ¥18,568
¥21,721 total
includes taxes & fees
Mar 8 - Mar 9
Drury Inn & Suites Southwest St. Louis

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
7.7 km from Midtown
9.4 out of 10, Exceptional, (486 reviews)
"Great place to stay, friendly staff, nice room, bathroom, and TV. "
United States
Natalie
The price is ¥27,949
¥32,138 total
includes taxes & fees
Mar 6 - Mar 7
The Knight Center at Washington University

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
Dogtown, 4.8 km from Midtown
9.4 out of 10, Exceptional, (1,003 reviews)
"Was perfect for a family stay. Nice rooms, quiet, close to Zoo and Science center."
United States
Joseph
The price is ¥21,625
¥25,502 total
includes taxes & fees
Mar 9 - Mar 10
Hampton Inn & Suites St. Louis at Forest Park

Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66
3.5 star property
17.4 km from Midtown
8.4 out of 10, Very Good, (1,418 reviews)
"Room, breakfast and location are all good. We stayed here three days for hidden valley ski, I don't regret the choice:)"
United States
Xiongyu
The price is ¥14,675
¥17,168 total
includes taxes & fees
Mar 4 - Mar 5
Best Western St. Louis-Kirkwood Route 66

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
27.1 km from Midtown
8.4 out of 10, Very Good, (1,005 reviews)
"The room was great. I enjoyed my stay. "
United States
Wanda
The price is ¥26,544
¥33,612 total
includes taxes & fees
Mar 9 - Mar 10
Ameristar Casino Resort and Spa

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.8 km from Midtown
9.2 out of 10, Wonderful, (848 reviews)
"Very good staff and great breakfast service."
United States
Denise
The price is ¥22,783
¥26,196 total
includes taxes & fees
Mar 15 - Mar 16
Holiday Inn Express & Suites Edwardsville by IHG

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
2.5 star property
16.3 km from Midtown
8.8 out of 10, Excellent, (130 reviews)
"Great stay!"
United States
Allyn
The price is ¥21,114
¥25,197 total
includes taxes & fees
Mar 9 - Mar 10
Hampton Inn By Hilton St Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Soulard

You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Top Midtown Hotel Reviews

Frequently asked questions

What is Midtown like?
Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel is a short 13-minute walk from Fox Theater, and it offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.
Where can I learn more about changing or cancelling my trip to Midtown?
To access more information about picking new dates or cancelling your trip to Midtown, go to https://www.expedia.com/service/.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks like Washington Avenue Historic District, Scott Joplin House State Historic Site, and Samuel Cupples House and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighborhood. Favorite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium, and Gateway Arch. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.

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