What's it like in Clayton?

Clayton is a welcoming neighborhood known for its array of dining options and sporting events. Be sure to check out Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center as part of your Clayton travel plans.

Where is the best hotel for a stay in Clayton?

Based on our traveler data, Clayton Plaza Hotel & Extended Stay is one of the top choices for your stay in Clayton. This hotel offers free breakfast and an indoor pool. Other good choices for your stay in the neighborhood include AC Hotel St. Louis Clayton and Le Méridien St. Louis Clayton .

How many hotels can I expect to find in Clayton?

Expedia has 21 hotels and other accommodations in Clayton to choose from, making this an ideal home base for exploring the greater St. Louis area.

If I need to cancel my hotel reservation in Clayton, will I receive a refund?

Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the best options available in Clayton.

Where can I learn more about changing or cancelling my trip to Clayton?

To find more details about rescheduling or cancelling your trip to Clayton, click here .

What are the top things to see and do in Clayton?

A few attractions you might want to check out while you're in Clayton are Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. When you're sightseeing in St. Louis, St. Louis Zoo and Tao Tennis Center are also worth a stop.

How can I get around Clayton and the greater St. Louis area?

Ready to get out and explore the city? Clayton Station is the closest metro station.

Top Clayton Hotels

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Our top choices for Clayton hotels

1. Clayton Plaza Hotel & Extended Stay

Clayton

Daniele

￥17,037 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

2. Le Méridien St. Louis Clayton

Clayton

Marsha

￥28,418 total

includes taxes & fees

Oct 18 - Oct 19

An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.

3. The Ritz-Carlton, St. Louis

Clayton

Kennedy

￥107,227 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop terrace with a fire feature, outdoor seating, and a city view.

4. Residence Inn By Marriott St. Louis Clayton

Clayton

Carol

￥33,190 total

includes taxes & fees

Nov 8 - Nov 9

A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.

5. AC Hotel St. Louis Clayton

Clayton

anthony

￥23,776 total

includes taxes & fees

Nov 8 - Nov 9

A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

6. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Clayton

Kevin

￥22,069 total

includes taxes & fees

Oct 18 - Oct 19

A modern lobby with a fireplace, seating area, and a kitchen counter.

7. Homewood Suites by Hilton St Louis - Galleria

Clayton

Katrina

￥22,255 total

includes taxes & fees

Oct 25 - Oct 26

A traditional Tudor-style building with a black awning labeled "28 Sally's Inn."

8. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Clayton

Jennifer

￥29,121 total

includes taxes & fees

Oct 18 - Oct 19

A courtyard with outdoor seating, a central fountain, and a view of a tower.

9. The Knight Center at Washington University

1.3 km from Clayton

Rosalyn

￥27,771 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

10. SpringHill Suites St. Louis Brentwood

2.4 km from Clayton

Aaron

￥23,367 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor patio with a fire pit, seating, and a building in the background.

11. Courtyard by Marriott St. Louis Brentwood

1.7 km from Clayton

Anna

￥22,813 total

includes taxes & fees

Nov 8 - Nov 9

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

12. The Cheshire

1.8 km from Clayton

Matthew

￥27,956 total

includes taxes & fees

Oct 25 - Oct 26

A rooftop restaurant with round tables, chairs, and a view of the city.

13. Moonrise Hotel

2.6 km from Clayton

Jessie

￥27,634 total

includes taxes & fees

Oct 19 - Oct 20

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

14. Drury Plaza Hotel St. Louis Brentwood

2.5 km from Clayton

Janell

￥24,116 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

15. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 3.9 km from Clayton

Melissa

￥25,873 total

includes taxes & fees

Nov 9 - Nov 10

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

16. Wingate by Wyndham St. Louis Airport

11.5 km from Clayton

Mary

￥18,196 total

includes taxes & fees

Oct 20 - Oct 21

A modern bathroom with a white vanity, a large mirror, and a framed cityscape picture.

17. Renaissance St. Louis Airport Hotel

10.1 km from Clayton

Anthony

￥21,926 total

includes taxes & fees

Oct 29 - Oct 30

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

18. Hyatt Select St. Louis Airport

10.7 km from Clayton

Daisy

￥21,633 total

includes taxes & fees

Oct 25 - Oct 26

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

19. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 5.1 km from Clayton

Kristina

￥35,732 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

20. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 5.6 km from Clayton

paullita jeanne

￥28,841 total

includes taxes & fees

Oct 18 - Oct 19

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Where to stay in Clayton

Find the best Clayton areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

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A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

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A large airplane suspended in a net structure in an urban setting with modern buildings in the background.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

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Top Clayton Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

8/10 Good

"Great location for the Arch. Rooms a little outdated but, overall good."

21C Museum Hotel St Louis

10/10 Excellent

"The pool and the hot tub are ten out of ten stars. The service was great as were the valets. The location was a bit barren at night but not dangerous, just not a ton of options. Security was great; bring your key everywhere. Coffee was good. Price was as expected. Dinner looked good, but we had kids, and it’s definitely more adult food. But the pool and hot tub is perfect for kids and we will definitely come back!"

Find hotels in Clayton, St. Louis

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Our top choices for Clayton hotels

1. Clayton Plaza Hotel & Extended Stay

2. Le Méridien St. Louis Clayton

3. The Ritz-Carlton, St. Louis

4. Residence Inn By Marriott St. Louis Clayton

5. AC Hotel St. Louis Clayton

6. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

7. Homewood Suites by Hilton St Louis - Galleria

8. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

9. The Knight Center at Washington University

10. SpringHill Suites St. Louis Brentwood

11. Courtyard by Marriott St. Louis Brentwood

12. The Cheshire

13. Moonrise Hotel

14. Drury Plaza Hotel St. Louis Brentwood

15. Hampton Inn & Suites St. Louis at Forest Park

16. Wingate by Wyndham St. Louis Airport

17. Renaissance St. Louis Airport Hotel

18. Hyatt Select St. Louis Airport

19. The Royal Sonesta Chase Park Plaza St. Louis

20. Home2 Suites by Hilton St. Louis/Forest Park

Where to stay in Clayton

Downtown St. Louis

Central West End

Creve Coeur

St. Charles Historic District

Downtown West

Top Clayton Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

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