St. Charles Vacation Rentals

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Check prices for these dates

In two weeks
Mar 13 - Mar 15
In two months
Apr 24 - Apr 26
In three months
May 22 - May 24
In four months
Jun 19 - Jun 21

Our top choices for St. Charles vacation rentals

TV

Vacation Home in Saint Charles

Two Bedroom Townhome near Streets
9.0 out of 10, Wonderful, (10 reviews)
"Great location, clean, and management was informative and reacted to any needs quickly. Would recommend to anyone."
United States
Nathan D.
The price is ￥17,369
￥47,423 total
includes taxes & fees
Feb 25 - Feb 26
Two Bedroom Townhome near Streets
Smart TV, books

Vacation Home in Saint Charles

Casa de Saint Charles
9.2 out of 10, Wonderful, (17 reviews)
"The home was perfect for our multi-family gathering. There was lots of room for everyone and the location was great for our needs."
United States
Karla Z.
The price is ￥22,114
￥50,258 total
includes taxes & fees
Mar 2 - Mar 3
Casa de Saint Charles
TV

Apartment in St. Charles Historic District

Main Street Balcony Apartment by StayLage!
9.6 out of 10, Exceptional, (36 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
The price is ￥24,885
￥68,617 total
includes taxes & fees
Feb 26 - Feb 27
Main Street Balcony Apartment by StayLage!
3 bedrooms, iron/ironing board, WiFi, bed sheets

Vacation Home in Saint Charles

The Below Deck Suite
9.0 out of 10, Wonderful, (2 reviews)
"Overall good place for a family. The neighborhood is quiet and there is a good amount of space. Easy to find and to get places. You will hear the people upstairs and one bed was very squeaky. It was very clean and the couches are very comfy. "
United States
Amy B.
The price is ￥15,155
￥36,341 total
includes taxes & fees
Mar 1 - Mar 2
The Below Deck Suite
Fridge, microwave, oven, stovetop

Vacation Home in Saint Charles

Home Near Main Street-Covered Patio-Hot Tub!
9.6 out of 10, Exceptional, (30 reviews)
"We absolutely loved our stay in St. Charles. This property was perfect for our family with plenty of space and very clean! Great communication and responsiveness from owner. We would definitely book this property again in the future. "
United States
Danielle T.
The price is ￥29,768
￥77,491 total
includes taxes & fees
Feb 25 - Feb 26
Home Near Main Street-Covered Patio-Hot Tub!
Smart TV, fireplace, computer monitors

Vacation Home in Saint Charles

Charming open 4bd and screen-in porch! Sleeps 10!
9.2 out of 10, Wonderful, (35 reviews)
"Stay here for 3 weeks. Place was just as described. Would recommend. Thank you "
United States
Eddy
The price is ￥29,768
￥77,491 total
includes taxes & fees
Feb 26 - Feb 27
Charming open 4bd and screen-in porch! Sleeps 10!
Fridge, microwave, oven, stovetop

Apartment in St. Charles Historic District

Historic Main St. Customs House Upstairs Apartment
9.6 out of 10, Exceptional, (36 reviews)
"Great Stay and great location! "
United States
Angela
The price is ￥22,547
￥57,930 total
includes taxes & fees
Feb 25 - Feb 26
Historic Main St. Customs House Upstairs Apartment
TV, books

Vacation Home in St. Charles Historic District

St. Charles 1860's Gem - Sleeps 6!
9.8 out of 10, Exceptional, (141 reviews)
"Another great stay! "
United States
Kate G.
The price is ￥18,789
￥38,738 total
includes taxes & fees
Feb 25 - Feb 26
St. Charles 1860's Gem - Sleeps 6!
Interior

Vacation Home in Saint Charles

Spacious 2 Bedroom Townhome by StayLage
7.8 out of 10, Good, (12 reviews)
"Perfect size"
United States
Barbie D.
The price is ￥16,534
￥46,307 total
includes taxes & fees
Feb 25 - Feb 26
Spacious 2 Bedroom Townhome by StayLage
Living area

Apartment in Saint Charles

The Cul-de-Sac Retreat
8.4 out of 10, Very Good, (9 reviews)
"Great house, great location - close to the St. Charles convention center"
United States
Joe H.
The price is ￥15,155
￥36,341 total
includes taxes & fees
Feb 26 - Feb 27
The Cul-de-Sac Retreat
Fridge, microwave, oven, stovetop

Vacation Home in St. Charles Historic District

The Original Custom House!
9.8 out of 10, Exceptional, (36 reviews)
"Location is perfect. Clean and exactly what we were looking for in a weekend get away. The common areas (living room and kitchen) are on the smaller side if you are wanting a place to gather but we were out and about most of the time so it was perfect for us. "
United States
Amanda G.
The price is ￥22,547
￥57,930 total
includes taxes & fees
Feb 25 - Feb 26
The Original Custom House!
Interior

Vacation Home in Saint Charles

The Olive House - Near Main Street- Fully rehabbed
8.8 out of 10, Excellent, (9 reviews)
"Great place to stay for the weekend. Only 1 bathroom can be a stretch if you’re used to having access to multiple. However, it’s a quick walk to Upshot or Lady Di’s for coffee or breakfast. "
United States
Rachel Y.
The price is ￥19,330
￥53,892 total
includes taxes & fees
Feb 25 - Feb 26
The Olive House - Near Main Street- Fully rehabbed
Exterior

Apartment in St. Charles Historic District

Stay on Main Historic Studio
9.0 out of 10, Wonderful, (33 reviews)
"Nice property.. Clean. "
United States
Belinda J.
The price is ￥13,528
￥31,947 total
includes taxes & fees
Mar 1 - Mar 2
Stay on Main Historic Studio
Smart TV

Vacation Home in St. Charles Historic District

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
9.6 out of 10, Exceptional, (68 reviews)
"The neighborhood was beautiful, close to shopping and activities!"
United States
Tami B.
The price is ￥28,067
￥75,381 total
includes taxes & fees
Mar 2 - Mar 3
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
Interior

Apartment in St. Charles Historic District

Amazing Renovated Historic Loft on Main Street
10.0 out of 10, Exceptional, (59 reviews)
"Great place and location. Owners were easy to work with."
United States
Cory M.
The price is ￥18,402
￥39,036 total
includes taxes & fees
Feb 25 - Feb 26
Amazing Renovated Historic Loft on Main Street
Fridge, microwave, oven, stovetop

Vacation Home in St. Charles Historic District

Historic 4‑BR Farmhouse • Steps to Main Street
9.8 out of 10, Exceptional, (23 reviews)
"Everything was perfect! Close to a bike trail and cute shops and bars. Pet friendly. Beautiful home! "
United States
Michelle B.
The price is ￥19,639
￥92,750 total
includes taxes & fees
Mar 10 - Mar 11
Historic 4‑BR Farmhouse • Steps to Main Street
Game room

Vacation Home in St. Charles Historic District

Madison House 1 -Walk to Main St
8.6 out of 10, Excellent, (17 reviews)
"The house was clean and well stocked, location was great, and plenty of street parking. "
United States
Brad K.
The price is ￥13,763
￥36,412 total
includes taxes & fees
Feb 25 - Feb 26
Madison House 1 -Walk to Main St
Interior

Apartment in St. Charles Historic District

The Lofts of North Main Street
9.6 out of 10, Exceptional, (164 reviews)
"Very clean, lovely and a great location. "
United States
Michelle M.
The price is ￥15,170
￥34,276 total
includes taxes & fees
Feb 25 - Feb 26
The Lofts of North Main Street
TV

Apartment in St. Charles Historic District

1st Capitol Mansion - Suite 401
7.6 out of 10, Good, (8 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is ￥15,309
￥38,174 total
includes taxes & fees
Feb 25 - Feb 26
1st Capitol Mansion - Suite 401
Fridge, microwave, oven, stovetop

Vacation Home in Saint Charles

Winter SALE,Cozy 2BR Chalet, Hot Tub 1.2 Acres!
8.8 out of 10, Excellent, (3 reviews)
"We loved the location for our travel needs and we had everything we needed for a family of two adults and two dogs. "
United States
Leslie R.
The price is ￥34,098
￥91,123 total
includes taxes & fees
Feb 26 - Feb 27
Winter SALE,Cozy 2BR Chalet, Hot Tub 1.2 Acres!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent
"Great service, and the room was perfect."
Joshua 1-night trip
Posted 21 hours ago
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Find out more about St. Charles

Search for holiday rentals in St. Charles on Expedia! You can easily find your home rentals, villas, holiday apartments in St. Charles using one of the methods below:

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Look no further and take a look at our great range of rental properties in St. Charles!

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

What are some of the best vacation rentals that St. Charles has to offer?

St. Charles 1860's Gem - Sleeps 6!: This St. Charles vacation home rental is located on a river and has a garden, a selection of books, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Some other top choices in St. Charles are 🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟 and 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo..

How many vacation rentals are there in St. Charles?

Expedia has 87 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and Lewis & Clark Boathouse and Nature Center.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.