Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and churches in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and churches in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the churches in this vibrant area.
Piazza del Carmine
You can learn about the history of Florence with a stop at Piazza del Carmine. Amble around this vibrant area's riverfront or experience its fascinating museums.
Things to do
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Florence Accademia Gallery Tour with Entrance Ticket Included
Small-Group Wine Tasting Experience in the Tuscan Countryside
Best of Florence Tour with David at Accademia & Duomo (with VIP option)
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Florence: Pasta exclusive making cooking class with Gelato
Santo Spirito Hotel Deals
Hotel Horto Convento
"Beautiful, quiet surrounds. Walking distance to all major landmarks in Florence. Very friendly and helpful staff. No restaurant on site but breakfast is lovely and Giovanni has wonderful recommendations for where to eat. I didn’t have them but I’m told the cocktails are delicious. Didn’t use the ..."
Reviewed on May 24, 2026
Palazzo Mannaioni Suites
"Clean place"
Reviewed on May 23, 2026
La Torre Del Cestello
Palazzo Oliveto
"Nice and clean place, staff are friendly and helpful. It was a raining day on the second day we stay, the reception girl went out and bough an umbrella for us to use during the stay. Really appreciate it!"
Reviewed on May 11, 2026
Residenza D'Epoca Al Numero 8
"Great location for getting to know the center of Florence. We had a suite and it was beautiful and roomy. There is a small elevator which is nice if you have a bit of luggage. The staff was very friendly and helpful."
Reviewed on May 21, 2026
1900 Artevita
"The Staff was so nice and very helpful and accommodating when I made a mistake with the dates of my reservation!"
Reviewed on May 18, 2026
Other neighborhoods around Santo Spirito
San Frediano
San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Piazza della Repubblica are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Uffizi Gallery and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Uffizi Gallery and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
Santo Spirito
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