Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area.
Piazza del Carmine
You can learn about the history of Florence with a stop at Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art scene.
Things to do
Florence Accademia Gallery Tour with Entrance Ticket Included
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
The Best Tour in Florence: Renaissance and Medici Tales
Best of Florence Walking Tour
Pisa, Siena and San Gimignano day trip from Florence
From Venice: 1-Way Bus Ticket to Florence or Vice Versa
Santo Spirito Hotel Deals
Hotel Horto Convento
An oasis of calm - it is not buzzy and over the top like many places in the tourist center. Instead, it is tranquil, in a good area within easy walking distance to most of what you want to see. We enjoyed our stay.
Reviewed on Oct 25, 2025
UNA Hotels Vittoria Firenze
Amazing place, love the decor!
Reviewed on Jul 28, 2025
Palazzo Mannaioni Suites
Awesome staff and a great location!
Reviewed on Oct 14, 2025
La Torre Del Cestello
I had an amazing stay! My room was great - spacious and clean - and the view from my room was incredible! I also found it to be in a great location - the walk from the train station was easy, and it’s close to the main attractions while also being far enough away to be a little quiet. I’d easily ...
Reviewed on Oct 15, 2025
Hostel Santa Monaca
Clean room , friendly staffs & very accessible to any amenities . Separate toilet , shower & lavatory specific for women only , away from male rooms & toilets . Have ample space for kitchen with utensils, tables & chairs . Highly recommended ! Love it
Reviewed on Sep 18, 2025
Foresteria Valdese di Firenze - Casa per Ferie
Very nice and interesting hotel located in Oltrarno, the artsy, lively area of Florence center, but a few blocks away from the crowds. Location is excellent! The hotel is quiet and has a wonderful history. I would stay there again.
Reviewed on Oct 21, 2025
Other neighborhoods around Santo Spirito
San Frediano
San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
Duomo
Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Santo Spirito
- Places of interest
- More Hotel Options in Santo Spirito
- Hotels in top Florence neighborhoods
- Other vacations you might like
More Hotel Options in Santo Spirito
Other Hotels near Santo Spirito, Florence
Expedia's Latest Trends
- Saga City Hotel
- Chisun Inn Nagoya
- The OneFive Fukuoka Tenjin
- M’s Hotel Nijojo Oike
- Four Seasons Resort The Nam Hai, Hoi An, Vietnam
- Jozankei View Hotel
- APA Hotel Nagoya Ekimae Kita
- KOKO HOTEL Sapporo Susukino
- Unwind Hotel & Bar Sapporo
- Bande Hotel Osaka
- Hotel Clover 33 Jalan Sultan
- Le Studio Gojo Takakura
- HOTEL SANSUI NAHA Ryukyu Onsen Naminoue-No-Yu
- Novotel London Brentford
- Hotels in Santorini
- Flights to Ishikawa Prefecture
- Flights from Bangkok (BKK) to Nagoya (NGO)
- Flights to Kyoto
- Flights from Casablanca (CMN) to Narita (NRT)
- Flights from Nagoya (NGO) to Chiang Mai (CNX)
- Flights from Osaka (KIX) to Santiago (SCL)
- Flights from San Diego (SAN) to Naha (OKA)
- Flights from Narita (NRT) to Mumbai (BOM)
- Flights from Narita (NRT) to Accra (ACC)
