A grand church interior with high vaulted ceilings, large columns, and a central altar.

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Our top choices for Santo Spirito hotels

1. Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (696 reviews)
"Beautiful, clean, amazing breakfast, really nice staff. 10/10 recommendation"
United States
Jennifer
The price is ¥24,359
¥29,402 total
includes taxes & fees
Aug 13 - Aug 14
Hotel Horto Convento

2. Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,147 reviews)
"Lovely place, perfect location. Easy to access!"
Canada
Jeanel
The price is ¥34,901
¥41,000 total
includes taxes & fees
Aug 5 - Aug 6
Palazzo Mannaioni Suites

3. UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze
4.0 star property
Santo Spirito
8.4 out of 10, Very Good, (1,000 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"
United Kingdom
Glenn
The price is ¥14,485
¥18,541 total
includes taxes & fees
Aug 13 - Aug 14
UNA Hotels Vittoria Firenze

4. 1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (198 reviews)
"Great place, very clean and as described in the listing. It has a good AC for the summer months and I highly recommend it."
United States
Jose Felipe
The price is ¥14,819
¥18,536 total
includes taxes & fees
Aug 17 - Aug 18
1900 Artevita

5. La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (183 reviews)
"Really nice, handy location"
United Kingdom
Kate
The price is ¥19,272
¥23,434 total
includes taxes & fees
Aug 6 - Aug 7
La Fonderia Firenze

6. Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (151 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is ¥17,777
¥21,790 total
includes taxes & fees
Aug 12 - Aug 13
Drom Florence Rooms & Apartments

7. Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (373 reviews)
"The air-conditioning was perfect, it was very quiet there and the room was spotless. The staff was so helpful to me in finding a restaurant and reserving a taxi. Breakfast was excellent and abundant. What a joy to stay there!"
United States
Jacqueline
The price is ¥22,273
¥26,735 total
includes taxes & fees
Aug 2 - Aug 3
Casa Santo Nome di Gesù

8. La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (282 reviews)
"Everything was great!"
United States
Edwin
The price is ¥16,877
¥21,173 total
includes taxes & fees
Aug 4 - Aug 5
La Torre Del Cestello

9. Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (105 reviews)
"I really enjoyed my stay here. The host was also extremely kind and helpful."
Belgium
Mary Mariam
The price is ¥10,650
¥13,950 total
includes taxes & fees
Aug 19 - Aug 20
Palazzo Oliveto

10. Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (42 reviews)
"We stayed with our children and the space was excellent and the location was close enough to walk to everything. "
United States
Juliet
The price is ¥12,824
¥31,243 total
includes taxes & fees
Jul 27 - Jul 28
Appartamenti degli Artisti by Mmega

11. Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (175 reviews)
"Really beautiful property and wonderful room. Hotel is immaculately clean and we thought the hotel had been renovated to a beautiful finish. We let the hotel know we were staying for our 10 year anniversary, and a bottle of Prosecco was left in our room with a note, which was extremely kind. A great location to stay in, just across the river. Passcode is provided for front door so can come and go as please. Have booked to stay in again in October!"
United Kingdom
Samantha
The price is ¥35,206
¥41,335 total
includes taxes & fees
Aug 8 - Aug 9
Ottantotto Firenze

12. Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (231 reviews)
"I had a lovely stay! Staff were helpful"
United States
Alloura
The price is ¥12,194
¥15,649 total
includes taxes & fees
Aug 4 - Aug 5
Foresteria Valdese di Firenze - Casa per Ferie

13. AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (233 reviews)
"This was our second time visiting Florence, staying at Astra. We loved the beauty of the rooms and surrounding gardens. The staff were very nice and helpful. It's the perfect blend of amenities and self-service for us. We had a B&B-style breakfast and service with 5-star rooms and vibes."
United Kingdom
Gary
The price is ¥39,175
¥45,700 total
includes taxes & fees
Jul 28 - Jul 29
AdAstra Suites

14. Home in Florence

Home in Florence
Santo Spirito
9.0 out of 10, Wonderful, (77 reviews)
"Wonderful stay again here-our second time. Beautifully clean, perfect location and friendly staff-thankyou for another lovely stay!"
United Kingdom
Victoria
The price is ¥12,850
¥16,370 total
includes taxes & fees
Jul 28 - Jul 29
Home in Florence

15. B&B Mia Palace

B&B Mia Palace
Santo Spirito
8.4 out of 10, Very Good, (123 reviews)
"Breakfast was excellent and what a lovely host. "
United Kingdom
Wayne
The price is ¥13,875
¥17,498 total
includes taxes & fees
Jul 30 - Jul 31
B&B Mia Palace

16. Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (164 reviews)
"Excellent place"
United States
Laura Patricia
The price is ¥18,443
¥22,895 total
includes taxes & fees
Aug 24 - Aug 25
Residenza D'Epoca Al Numero 8

17. Mamo Florence - Aleardi Roof Apartment

Mamo Florence - Aleardi Roof Apartment
Santo Spirito
10.0 out of 10, Exceptional, (1 review)
"Excelente lugar y relacion precio - estancia"
Mexico
Roberto Carlos
The price is ¥17,468
¥42,872 total
includes taxes & fees
Aug 2 - Aug 3
Mamo Florence - Aleardi Roof Apartment

18. Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (200 reviews)
"Staff very good ! Good ! clean room"
United States
Salomon
The price is ¥10,425
¥13,144 total
includes taxes & fees
Jul 31 - Aug 1
Hotel Firenze 2000

19. Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (130 reviews)
"Amazing location, charming hotel and great breakfast"
Sweden
Carin
The price is ¥40,388
¥47,035 total
includes taxes & fees
Aug 23 - Aug 24
Oltrarno Splendid

20. Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is ¥90,903
¥102,601 total
includes taxes & fees
Jul 30 - Jul 31
Torre di Bellosguardo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Cathedral of Santa Maria del Fiore and Piazza del Duomo are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Signoria and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Vibrant Atmosphere: Experience the lively ambiance of Piazza Santo Spirito, where locals gather and cultural events thrive.
  • Rich Cultural Heritage: Explore the stunning Church of Santo Spirito and the historic Palazzo Ridolfi, showcasing Florentine Renaissance art.
  • Outdoor Experiences: Relax in charming parks and enjoy leisurely strolls through picturesque streets.
  • Wine Tours: Indulge in wine tours that highlight Tuscany's renowned vineyards and local flavors.
  • Unique Accommodations: Stay in stylish hotels or cozy B&Bs that blend modern comfort with historic charm.

Find great hotels near Santo Spirito

Discover a charming selection of accommodations in Santo Spirito, Florence, where you can enjoy the unique blend of city living and historic allure. Choose from stylish hotels and cozy bed & breakfasts that offer a pet-friendly atmosphere and delightful shopping experiences. Explore options featuring antique furniture and the distinctive ambiance of palazzo ridolfi, all while being close to the artistic wonders of Fra Bartolomeo and the vibrant neighborhood of Santa Croce.

  • The Social Hub Florence Lavagnini: Located approximately 2km from Santo Spirito, The Social Hub Florence Lavagnini is a 4-star hotel that caters to adventurous travelers and business professionals alike. With a guest rating of 9.0 out of 10, this property offers an exciting range of onsite and nearby adventure sports and recreational activities. Guests can enjoy modern amenities and a vibrant atmosphere that fosters social interaction, making it an ideal spot for those looking to connect with fellow travelers while exploring the beautiful city of Florence.
  • B&B Hotel Firenze Pitti Palace al Ponte Vecchio: Just 1km from Santo Spirito, this 4-star hotel boasts a guest rating of 9.0 out of 10 and is especially suited for families and adventure seekers. The B&B Hotel Firenze Pitti Palace al Ponte Vecchio provides convenient amenities for children, including babysitting services. Guests can also take advantage of nearby bicycle rentals for a unique way to explore Florence. This hotel combines family-friendly features with an adventurous spirit, ensuring a memorable stay for all.
  • Grand Hotel Cavour: Situated about 2km from Santo Spirito, the Grand Hotel Cavour is a luxurious 4-star establishment with an impressive guest rating of 9.2 out of 10. Located in the bustling shopping district, this hotel appeals to families and shopping enthusiasts. Amenities for children, such as onsite babysitting services, enhance the family-friendly atmosphere. Guests can indulge in the hotel’s elegant setting while enjoying easy access to local shops and attractions, making it a delightful choice for a family vacation.

Where to stay near Santo Spirito

Discover the charm of Santo Spirito, Florence, where culture and history intertwine in this vibrant neighborhood. Stroll through Piazza Santo Spirito, soaking in the lively atmosphere surrounded by friendly locals. Explore the rich heritage of the Florentine Renaissance and relax in seclusion, all while enjoying the trendy yet luxurious vibe. With romantic spots and historical treasures nearby, Santo Spirito promises an unforgettable experience in the heart of Florence.

  • Florence: As the vibrant heart of Tuscany, Florence invites travelers to immerse themselves in its rich culture and history. With a steady influx of visitors year-round, the city shines especially bright from March to April and September. Here, you can explore charming piazzas, indulge in shopping sprees, and enjoy relaxing spa experiences. The historic landmarks, including the iconic bridges and the bustling tourist precinct, are just a stone's throw away, making Florence a perfect base for your Tuscan adventure.
  • Historic Centre of Florence: Located a mile from Santo Spirito, the Historic Centre of Florence is a UNESCO World Heritage site filled with exquisite architecture and timeless charm. This neighborhood experiences a surge of visitors from July to September, drawn by its cultural offerings. Explore public markets brimming with local produce and arts, and take in the breathtaking views from historic bridges. Its proximity to beautifully adorned piazza squares ensures that there's always something captivating around every corner.
  • Duomo: Just 1km from Santo Spirito, the Duomo neighborhood is renowned for its stunning cathedral and lively atmosphere. Visitors flock here during the summer months, particularly from July to September, to enjoy the vibrant shopping areas and bustling public markets. The area is steeped in history, with picturesque piazzas and cultural landmarks creating an enchanting backdrop. Be sure to capture the essence of Florence by experiencing the neighborhood’s unique blend of art, history, and modern-day charm.

Things to do near Santo Spirito

Shopping

Santo Spirito offers a vibrant shopping scene with local boutiques and artisan shops showcasing handmade crafts and unique souvenirs. Don’t miss the Mercato di Santo Spirito, where you can find fresh produce and local delicacies, perfect for thoughtful gifts and a taste of Tuscany.

Recreation

Experience tranquility at Elysium Spa, where you can indulge in rejuvenating massages and soothing facials. For outdoor relaxation, stroll along the Arno River and enjoy the scenic views, or participate in a yoga session in Piazza Santo Spirito for a blend of wellness and culture.

Adventure

Experience the thrill of motor racing at the Mugello Circuit, located 27km from Santo Spirito. Feel the adrenaline as you watch high-speed races or take part in track days, surrounded by the scenic Tuscan landscape and a vibrant atmosphere that captures the spirit of adventure.

Nightlife

In Santo Spirito, enjoy a lively evening at Caffè Letterario for a cozy drink or explore the vibrant atmosphere at Caffè degli Artigiani. For a more energetic scene, check out Sodo for craft cocktails and music that keeps the night alive.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santo Spirito

Santo Spirito in Florence offers a delightful mix of culture, history, and outdoor experiences. Visitors can explore the charming piazza, visit the stunning church, and appreciate the historic palace. The area is perfect for families and culture enthusiasts alike, with highlights including San Spirito and Santo Spirito Square. Whether you're wandering through the streets or enjoying local cuisine, Santo Spirito promises a memorable vacation experience.

  • Cathedral of Santa Maria del Fiore: This iconic cathedral, known for its stunning Renaissance dome designed by Brunelleschi, stands as a symbol of Florence. Its intricate façade and beautiful frescoes inside offer a captivating glimpse into the city’s rich religious and artistic heritage.
  • Ponte Vecchio: The oldest and most famous bridge in Florence, Ponte Vecchio is lined with shops that sell jewelry and art. Its picturesque views of the Arno River and vibrant atmosphere make it a perfect spot to soak in the local culture.
  • Uffizi Gallery: Home to an extensive collection of priceless artworks, the Uffizi Gallery showcases masterpieces by artists like Botticelli and Michelangelo. Walking through its halls allows you to experience the evolution of Renaissance art in an inspiring setting.

Best time to go to Santo Spirito

The best time to visit Santo Spirito is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are moderately high and weather is sunny. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Flying into Santo Spirito, Florence, is convenient with major airports nearby. Florence Airport (FLR-Peretola) is located 5km away, with luxurious options like the 5-star Bernini Palace and Palazzo Montebello, both offering shuttle services. Bologna Airport (BLQ-Guglielmo Marconi) is 85km away, featuring the Grand Hotel Majestic and Starhotels Excelsior, which also provide shuttle services. Lastly, Pisa Airport (PSA-Galileo Galilei) is 68km away, with top hotels like Bagni di Pisa Palace, ensuring easy access to the city. Each hotel offers various transportation options, making it easy for tourists to navigate their way into the beautiful streets of Florence.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on our traveler data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighborhood include La Torre Del Cestello and UNA Hotels Vittoria Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 521 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Favorite places to visit in the surrounding area include Piazza di Santa Maria Novella, Piazza della Signoria, and Cathedral of Santa Maria del Fiore. When you're sightseeing in Florence, Piazza del Duomo and Piazza del Carmine are also worth a stop.

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