Visit Sant' Ambrogio
Popular places to visit
Uffizi Gallery
Art lovers will be in their element in this famous museum, home to the most extensive and important collection of masterpieces in the world.
Ponte Vecchio
Take a trip over Florence’s iconic bridge, spared by the Nazis for its beauty and home to jewelers for more than four centuries.
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Cathedral of Santa Maria del Fiore
The “Saint Mary of the Flower” cathedral and its towering dome have come to symbolize Florence.
Piazza del Duomo
Giotto’s Bell Tower, the resplendent Baptistery, as well as the cathedral and its dome draw the crowds to this square in the heart of the city.
Palazzo Vecchio
After visiting Palazzo Vecchio, make a plan to see the other sights and activities in Florence. Amble around this vibrant area's riverfront or experience its fascinating museums.
Things to do
Florence Accademia Gallery Tour with Entrance Ticket Included
Tuscany Tour from Florence: Siena, San Gimignano, Pisa & Chianti
Florence: Evening Guided Walking Tour of Mystery, Scandal, and Secrets
Brunelleschi's Dome and Cathedral Complex Reserved Ticket
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
From Venice: 1-Way Bus Ticket to Florence or Vice Versa
Sant' Ambrogio Hotel Deals
Hotel Bodoni
Clean room, convenient location, lovely terrace
Reviewed on Nov 10, 2025
Hotel Bavaria
Nicest hotel staff and super convenient location. Would stay again if visiting Florence.
Reviewed on Nov 5, 2025
Hotel Cardinal Of Florence
The location is excelent. Very convinience.
Reviewed on Sep 27, 2025
B&B di Piazza del Duomo
Nice staff, clean room. Location second to none. Wifi. Free fizzy water at reception. I could look out my window and see il Duomo. For breakfast I went to the Museum Cafe, a 2 minute walk from the B&B to the piazza. Breakfast was great. Ask for the FRESH orange juice. Loved it.
Reviewed on Nov 14, 2025
Hotel Regency
Awesome stay, large and comfortable room. Staff are amazing, friendly and helpful and really make you feel at home! Delicious breakfast and the hotel is beautiful. Location is great as well, especially if you are coming by car, since it is a short walk to all the sites but just outside the really ...
Reviewed on Nov 8, 2025
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
Outstanding hotel and a remarkable experience staying there. The room was large and beautifully decorated as the rest of the hotel. Service was impeccable and friendly. Food was great. Lovely and intimate atmosphere. Attention to details and distinctive effort to attend to our needs. The hotel manager ...
Reviewed on Nov 14, 2025
Other neighborhoods around Sant' Ambrogio
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Via de' Calzaiuoli and Piazza della Repubblica are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Santa Croce
Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.
Santissima Annunziata
Travelers come to Santissima Annunziata for its colorful gardens, and you can see top attractions like Piazza Massimo D'Azeglio and Santissima Annunziata Square while you're in town.
Duomo
Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
San Niccolò
If you're spending some time in San Niccolò, Arno River and Piazzale Michelangelo are top sights worth seeing.
