Find hotels in Sant' Ambrogio, Florence

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sant' Ambrogio hotels

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
5.0 star property
Sant' Ambrogio
10.0 out of 10, Exceptional, (14 reviews)
"This hotel was quite the find! The staff was amazing, attentive, respectful. The amenities, attention to detail, experience was amazing! We will definitely be back."
United States
Nicole
The price is ¥49,741
¥57,659 total
includes taxes & fees
Mar 8 - Mar 9
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

Appartamento Puccini

Appartamento Puccini
Sant' Ambrogio
7.8 out of 10, Good, (76 reviews)
"The apartment is located perfectly"
Germany
Thomas
The price is ¥14,446
¥21,776 total
includes taxes & fees
Apr 3 - Apr 4
Appartamento Puccini

Casa Rovai Guest House

Casa Rovai Guest House
Sant' Ambrogio
8.6 out of 10, Excellent, (117 reviews)
"Great stay!"
Canada
Kim
The price is ¥15,048
¥18,760 total
includes taxes & fees
Mar 15 - Mar 16
Casa Rovai Guest House

Santa Croce Place by Mmega

Santa Croce Place by Mmega
Sant' Ambrogio
6.8 out of 10, (5 reviews)
"The apartment was not kept well. Consumables like sugar, detergent etc. kept under lock and key. Mosquitoes were a hassle. The bathroom was very tiny. The bedroom is next to the road, so was very noisy. Although it is located at an excellent location."
India
Sachit
The price is ¥14,026
¥32,349 total
includes taxes & fees
Mar 5 - Mar 6
Santa Croce Place by Mmega

Iris Apartments by Mmega

Iris Apartments by Mmega
Sant' Ambrogio
7.8 out of 10, Good, (12 reviews)
"Excellent location bit a bit noisy at night."
United States
Stephen
The price is ¥14,026
¥32,349 total
includes taxes & fees
Mar 8 - Mar 9
Iris Apartments by Mmega

Borgo Pinti Cozy Flat 

Borgo Pinti Cozy Flat 
Sant' Ambrogio
7.4 out of 10, Good, (3 reviews)
"Excellent property beyond our expectations. After a stressful day of traveling internationally, the key and entry taxed us. The key continued to be an issue for us (skeleton key with 4 locks). But otherwise, it's location and the property itself, awesome!"
United States
Stephanie
Borgo Pinti Cozy Flat 

Residenza d'Epoca White Room

Residenza d'Epoca White Room
Sant' Ambrogio
7.4 out of 10, Good, (64 reviews)
"LOVED this place! It’s huge, cute, clean, centrally located, and has a super nice bathroom. Also has your own A/C unit which was awesome! Highly recommend especially for the price."
United States
Amelia
Residenza d'Epoca White Room

Villa Tortorelli

Villa Tortorelli
Sant' Ambrogio
9.6 out of 10, Exceptional, (68 reviews)
"The staff were lovely and made sure we were comfortable during our stay."
Australia
Rihana
The price is ¥23,955
¥28,557 total
includes taxes & fees
Mar 6 - Mar 7
Villa Tortorelli

Palazzo dei Ciompi Suites

Palazzo dei Ciompi Suites
Sant' Ambrogio
7.6 out of 10, Good, (396 reviews)
"Amazing staff "
United States
Gavin
The price is ¥16,344
¥20,186 total
includes taxes & fees
Mar 15 - Mar 16
Palazzo dei Ciompi Suites

Dimora del Cardinale - Residenza d'epoca

Dimora del Cardinale - Residenza d'epoca
Sant' Ambrogio
9.8 out of 10, Exceptional, (56 reviews)
"Most memorable magical stay staff was extremely helpful. Place was beautiful beyond our expectations area was perfect to walk to everything. Highly recommend this location. "
United States
Miriam
The price is ¥18,420
¥22,469 total
includes taxes & fees
Mar 8 - Mar 9
Dimora del Cardinale - Residenza d'epoca

Don Giovanni by Mmega

Don Giovanni by Mmega
Sant' Ambrogio
9.0 out of 10, Wonderful, (7 reviews)
"Perfect location Very clean Nicely appointed"
United States
Luanne
The price is ¥23,667
¥42,954 total
includes taxes & fees
Mar 9 - Mar 10
Don Giovanni by Mmega

Wine Apartments Florence Colorino

Wine Apartments Florence Colorino
Sant' Ambrogio
7.0 out of 10, Good, (2 reviews)
"It was clean and spacious."
United States
Joseph
Wine Apartments Florence Colorino

Alfieri9

Alfieri9
3.0 star property
Sant' Ambrogio
9.6 out of 10, Exceptional, (158 reviews)
"Hotel was in a nice quiet neighborhood, but still only a short walk to main attractions. The breakfast was excellent. Staff interactions were good."
United States
Colin
Alfieri9

Locanda Orchidea - B&B

Locanda Orchidea - B&B
Sant' Ambrogio
9.2 out of 10, Wonderful, (233 reviews)
"Perfect location, superb room, + wonderful staff - a brilliant stay all round! "
United Kingdom
TARA
Locanda Orchidea - B&B

Hotel Villa Liana

Hotel Villa Liana
3.0 star property
Sant' Ambrogio
8.6 out of 10, Excellent, (349 reviews)
"the breakfast was delicious!"
United States
Catherine
The price is ¥24,077
¥28,692 total
includes taxes & fees
Mar 15 - Mar 16
Hotel Villa Liana

Hotel Bavaria

Hotel Bavaria
1.0 star property
Sant' Ambrogio
8.2 out of 10, Very Good, (421 reviews)
"Simple but cost effective hotel. Amazing location."
United Kingdom
Bernardo Correa
The price is ¥9,602
¥11,850 total
includes taxes & fees
Mar 8 - Mar 9
Hotel Bavaria

B&B di Piazza del Duomo

B&B di Piazza del Duomo
Sant' Ambrogio
9.2 out of 10, Wonderful, (258 reviews)
"Sweetly decorated and cozy, welcoming, kind concierge and an awesome location! "
United States
Jamie
The price is ¥23,390
¥27,936 total
includes taxes & fees
Mar 17 - Mar 18
B&B di Piazza del Duomo

Hotel Bodoni

Hotel Bodoni
2.0 star property
Sant' Ambrogio
8.2 out of 10, Very Good, (802 reviews)
"Clean, convenient, friendly staff"
United States
Jing
The price is ¥15,467
¥18,663 total
includes taxes & fees
Mar 11 - Mar 12
Hotel Bodoni

Breathtaking 4BD Apt 5min Walk to Duomo

Breathtaking 4BD Apt 5min Walk to Duomo
Sant' Ambrogio
8.0 out of 10, Very Good, (6 reviews)
"The apartment was in excellent arrangement—clean, comfortable, and beautifully decorated. We especially loved how close it was to the Duomo; the location couldn’t have been better. Everything was perfect and made our time in Florence truly special."
United States
Lizette
Breathtaking 4BD Apt 5min Walk to Duomo

Oriuolo Prestige by Mmega

Oriuolo Prestige by Mmega
Sant' Ambrogio
9.0 out of 10, Wonderful, (7 reviews)
"I've stayed here a couple of times and surely I will come again. it's well located and it is close to the Duomo. The apartment is very confortable. "
United States
Jorge
The price is ¥15,778
¥36,115 total
includes taxes & fees
Mar 7 - Mar 8
Oriuolo Prestige by Mmega
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Sant' Ambrogio Hotel Reviews

Frequently asked questions

What's it like in Sant' Ambrogio?
Guests are sure to enjoy their time checking out all that Florence's Sant' Ambrogio neighborhood has to offer. Be sure to check out Jewish Museum and Piazza Massimo D'Azeglio as part of your Sant' Ambrogio travel plans.
What's the best accommodation in Sant' Ambrogio?
Based on Expedia customer reviews, Dimora del Cardinale - Residenza d'epoca is the highest ranked property in Sant' Ambrogio. This B&B is a short 7-minute walk from Cathedral of Santa Maria del Fiore, and it offers free WiFi and comfy beds. Other favorite options in the area include Hotel Regency and Villa Tortorelli.
How many hotels will I find in Sant' Ambrogio?
If you're searching for places to stay in Florence, Expedia has something to meet your needs with 521 Sant' Ambrogio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Sant' Ambrogio, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review top deals in Sant' Ambrogio.
Where can I learn more about changing or cancelling my trip to Sant' Ambrogio?
To find more details about rescheduling or cancelling your trip to Sant' Ambrogio, head over to our customer service page.
What is there to do around this Florence neighborhood?
Landmarks in Sant' Ambrogio that you won't want to miss include Great Synagogue of Florence and Church of Santa Maria Maddalena dei Pazzi. Jewish Museum and Piazza Massimo D'Azeglio are also a couple of places to visit in the neighborhood. Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are some favorite places to visit in the area around Sant' Ambrogio. When you're sightseeing in Florence, FiesoleBike Day Tours and Mercato di Sant'Ambrogio are also worth a stop.

Explore a world of travel with Expedia