Santo Spirito

Florence

Brancacci Chapel which includes heritage architecture, a church or cathedral and a sunset
Brancacci Chapel which includes heritage architecture and a church or cathedral
Brancacci Chapel featuring heritage elements
Brancacci Chapel which includes a church or cathedral and heritage architecture
Arcetri which includes a city and landscape views

Popular places to visit

Things to do


Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13, Florence, FI
The price is ¥17,695 per night from Nov 18 to Nov 19
¥17,695
¥21,935 total
Nov 18 - Nov 19
includes taxes & fees
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (577 reviews)
Friendly and helpful staff, gorgeous hotel, nice quiet location

Reviewed on Oct 14, 2025

Hotel Horto Convento
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
The price is ¥23,091 per night from Oct 31 to Nov 1
¥23,091
¥27,870 total
Oct 31 - Nov 1
includes taxes & fees
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (988 reviews)
Amazing place, love the decor!

Reviewed on Jul 28, 2025

UNA Hotels Vittoria Firenze
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,040 reviews)
Awesome staff and a great location!

Reviewed on Oct 14, 2025

Palazzo Mannaioni Suites
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8, Florence, FI
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...
9/10 Wonderful! (215 reviews)
I had an amazing stay! My room was great - spacious and clean - and the view from my room was incredible! I also found it to be in a great location - the walk from the train station was easy, and it’s close to the main attractions while also being far enough away to be a little quiet. I’d easily ...

Reviewed on Oct 15, 2025

La Torre Del Cestello
Hostel Santa Monaca

Hostel Santa Monaca

Via Santa Monaca 6, Florence, FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Uffizi Gallery ...
8/10 Very Good! (60 reviews)
Clean room , friendly staffs & very accessible to any amenities . Separate toilet , shower & lavatory specific for women only , away from male rooms & toilets . Have ample space for kitchen with utensils, tables & chairs . Highly recommended ! Love it

Reviewed on Sep 18, 2025

Hostel Santa Monaca
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49, Florence, FI
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (185 reviews)
Front desk staff was amazing and very friendly and helpful . The room had all the amenities needed including fridge and hair dryer. Only thing they could improve is screens on windows for mosquitoes.

Reviewed on Oct 17, 2025

Foresteria Valdese di Firenze - Casa per Ferie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

Brancacci Chapel which includes a church or cathedral and heritage architecture

San Frediano

San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.

San Frediano
Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

San Giovanni
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Historic Centre of Florence


Santo Spirito