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Jul 30 - Jul 31
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Discover 469 Santo Spirito hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Art Hotel Villa Agape
Stroll through the beautifully landscaped garden, surrounded by vibrant flower beds and a serene central water feature.

Art Hotel Villa Agape

4.0 star property
9.8 out of 10, Exceptional, (1001)
"The property is very beautiful and the food is excellent "
The price is ￥24,011
￥28,822 total
includes taxes & fees
Aug 3 - Aug 4
Art Hotel Villa Agape
La Fonderia Firenze
Enjoy meals and gatherings in this kitchen with oven, sink, and ample counter space.

La Fonderia Firenze

9.6 out of 10, Exceptional, (160)
"Great location, wonderful staff, awesome room. Will definely stay again! "
The price is ￥14,224
￥17,712 total
includes taxes & fees
Aug 24 - Aug 25
La Fonderia Firenze
Ruby Bea Hotel Florence
Relax in the BEA + DANTE lounge area, featuring a central bar with a curved countertop and comfortable seating.

Ruby Bea Hotel Florence

4.0 star property
9.6 out of 10, Exceptional, (298)
"Good place to stay nowadays. "
The price is ￥16,123
￥20,146 total
includes taxes & fees
Aug 6 - Aug 7
Ruby Bea Hotel Florence
IQ Hotel Firenze
Relax by the pool in a unique, inviting atmosphere with panoramic views of the surroundings.

IQ Hotel Firenze

4.0 star property
9.6 out of 10, Exceptional, (909)
"Great place nice friendly staff"
The price is ￥21,445
￥26,001 total
includes taxes & fees
Aug 10 - Aug 11
IQ Hotel Firenze
Ottantotto Firenze
Stroll through the serene garden, surrounded by lush greenery and ornate stone urns.

Ottantotto Firenze

9.6 out of 10, Exceptional, (160)
"Beautiful rooms and friendly staff "
The price is ￥33,441
￥39,186 total
includes taxes & fees
Aug 3 - Aug 4
Ottantotto Firenze
Hotel Horto Convento
Relax in this inviting living area with a tufted sofa, armchair, and coffee table.

Hotel Horto Convento

4.0 star property
9.8 out of 10, Exceptional, (543)
"I would definitely stay there again"
The price is ￥20,152
￥24,578 total
includes taxes & fees
Aug 2 - Aug 3
Hotel Horto Convento
La Torre Del Cestello
Relax in this stylish living room with a comfortable sofa, flat-screen TV, and a beautiful orchid plant.

La Torre Del Cestello

9.0 out of 10, Wonderful, (194)
"Great location. Clean and comfortable rooms and super helpful and communicative staff. "
The price is ￥15,680
￥19,314 total
includes taxes & fees
Jul 31 - Aug 1
La Torre Del Cestello
Palazzo Mannaioni Suites
Relax in a cozy space with a rustic charm, featuring a comfortable sofa and armchair, a flat-screen TV, and a large pendant light.

Palazzo Mannaioni Suites

4.0 star property
9.2 out of 10, Wonderful, (1020)
"Great location, rooms, and lovely staff. Enjoyed our stay. "
Palazzo Mannaioni Suites
Mamo Florence - Bice & Krizia Apartments
Enjoy a comfortable stay in this apartment with a sofa, dining table for four, and a kitchen with modern appliances.

Mamo Florence - Bice & Krizia Apartments

The price is ￥15,459
￥34,568 total
includes taxes & fees
Aug 8 - Aug 9
Mamo Florence - Bice & Krizia Apartments
Mamo Florence - Maddalena Apartment
Compact kitchen with a traditional tile backsplash, stainless steel stove, oven, and small sink.

Mamo Florence - Maddalena Apartment

10.0 out of 10, Exceptional, (1)
"Fantastic top floor apartment in medieval building just beyond the Palazzo Pitti on the quieter side of the Arno. There's a cafe and a supermarket nearby, a very popular pizzeria and Santo Spirito 5 minutes away and the heart of the city is just 10 to 15 minutes walk away. The apartment had everything we needed for a family of 5, great cooking facilities and a neat and tidy bathroom. We'd definitely stay there again if we return to Florence. "
The price is ￥15,459
￥33,707 total
includes taxes & fees
Aug 10 - Aug 11
Mamo Florence - Maddalena Apartment
Mamo Florence - Cloe Apartment
Kitchen features a central island with an oven, sink, and glass-front cabinets.

Mamo Florence - Cloe Apartment

10.0 out of 10, Exceptional, (2)
"This was a fantastic, spacious apartment for our family of 4. We initially had an issue with the WiFi and host communicated very well, and sent a technician to fix it very quickly. The neighborhood is wonderful - far enough away from the crowds of tourists to enjoy a quieter side of Florence, but close enough to walk 10 minutes to be in the center of all of the major tourist attractions. "
The price is ￥15,343
￥35,301 total
includes taxes & fees
Aug 28 - Aug 29
Mamo Florence - Cloe Apartment
Oltrarno Splendid
Relax in a beautifully furnished bedroom with a large bed, clawfoot bathtub, and mounted television.

Oltrarno Splendid

9.8 out of 10, Exceptional, (87)
"Great that it was completely separate and quiet - an oasis in a hot and bustling city yet very close to sights, restaurants etc."
The price is ￥27,755
￥32,942 total
includes taxes & fees
Aug 3 - Aug 4
Oltrarno Splendid
Drom Florence Rooms & Apartments
Classic charm abounds in this beautifully maintained building with a white arched entrance and lush greenery.

Drom Florence Rooms & Apartments

9.8 out of 10, Exceptional, (124)
"I loved this place and made me want to go back and stay for a while!!! The host was so nice and accommodating. This is a must book place if you are looking for Florence charm and don’t mind a 20 "
Drom Florence Rooms & Apartments
AdAstra Suites
Relax in a spacious room with a large bed, chair, and artwork, featuring a window with curtains.

AdAstra Suites

9.8 out of 10, Exceptional, (213)
"Staff was absolutely wonderful!!! "
The price is ￥36,989
￥43,089 total
includes taxes & fees
Aug 11 - Aug 12
AdAstra Suites
L'Antica Porta Boutique B&B
Enjoy a restful stay in this cozy room with a neatly made bed, desk, and TV, offering a balcony view.

L'Antica Porta Boutique B&B

9.2 out of 10, Wonderful, (9)
"Nice place and really quiet during night hours, definitely a great place to stay, not that far from florence city centre"
The price is ￥14,342
￥17,842 total
includes taxes & fees
Aug 3 - Aug 4
L'Antica Porta Boutique B&B
Palazzo D'Oltrarno - Residenza D'Epoca
Stroll through the serene garden to the classical building's central entrance, flanked by windows with shutters.

Palazzo D'Oltrarno - Residenza D'Epoca

9.4 out of 10, Exceptional, (37)
"Gulia & Guissepe were so friendly and accommodating during our check in and stay. Great hidden gem as the property asked all to keep silence; great to have a quiet sanctuary away from the hubbub of city life! Nice view from our #5."
The price is ￥13,734
￥17,174 total
includes taxes & fees
Aug 3 - Aug 4
Palazzo D'Oltrarno - Residenza D'Epoca
SPIRIT OF FLORENCE Boutique Rooms
Relax in a stylish room with a large bed, seating area, and large window offering views of the outside.

SPIRIT OF FLORENCE Boutique Rooms

10.0 out of 10, Exceptional, (21)
"My husband and I enjoyed our stay here! Large rooms and bathrooms, wonderful location, and great staff! "
The price is ￥27,597
￥32,422 total
includes taxes & fees
Aug 9 - Aug 10
SPIRIT OF FLORENCE Boutique Rooms
Torre di Bellosguardo
Enjoy a serene escape amidst the city's vibrant urban landscape.

Torre di Bellosguardo

4.0 star property
9.0 out of 10, Wonderful, (97)
"Amazing hotel and Staff! Definitely coming here again during our next trip to Italy!"
The price is ￥80,836
￥91,321 total
includes taxes & fees
Aug 10 - Aug 11
Torre di Bellosguardo
Hotel Firenze 2000
Experience the charm of Italy at Youth Firenze 2000, featuring a traditional Italian facade with a tiled roof and a welcoming entrance.

Hotel Firenze 2000

2.0 star property
7.2 out of 10, Good, (167)
"The staff was very nice!"
The price is ￥9,216
￥11,688 total
includes taxes & fees
Aug 2 - Aug 3
Hotel Firenze 2000
Mamo Florence - Ardiglione Apartment
Relax in this stylish living room with a sofa, coffee table, and large window offering a view of the outdoors.

Mamo Florence - Ardiglione Apartment

The price is ￥38,493
￥78,699 total
includes taxes & fees
Aug 7 - Aug 8
Mamo Florence - Ardiglione Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito
Arcetri showing a bridge and a river or creek
Historic Centre of Florence map

Historic Centre of Florence

9 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo featuring heritage architecture and street scenes as well as a small group of people
Duomo map

Duomo

Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.

Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes
Santa Maria Novella map

Santa Maria Novella

Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.

Uffizi Gallery which includes street scenes as well as a large group of people
San Giovanni map

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Piazza Santa Croce showing a city and street scenes
Santa Croce map

Santa Croce

One of the historic districts of Florence has a network of medieval streets lined with opulent churches, leather stores, markets and atmospheric restaurants.

Top Santo Spirito Hotel Reviews

UNA HOTELS Vittoria Firenze

UNA HOTELS Vittoria Firenze

10/10 Excellent
"Amazing place, love the decor!"
jordan 1-night trip
Posted 1 day ago
UNA HOTELS Vittoria Firenze

Frequently asked questions

What is Santo Spirito like?

Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.

What's the best accommodation in Santo Spirito?

Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 9-minute walk from Ponte Vecchio, and it offers free breakfast and free WiFi. Other favorite options in the area include AdAstra Suites and Ottantotto Firenze.

How many hotels can I expect to find in the Santo Spirito area?

Expedia has 469 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.

If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.

Where can I learn more about changing or cancelling my trip to Santo Spirito?

To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.

What can I see and do in this Florence neighborhood?

Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. Uffizi Gallery and Cathedral of Santa Maria del Fiore are some favorite places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.