What is Santo Spirito like?

Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Arno River as part of your Santo Spirito travel plans.

What's the best accommodation in Santo Spirito?

Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favorite options in the area include SPIRIT OF FLORENCE Boutique Rooms and La Fonderia Firenze .

How many hotels can I expect to find in the Santo Spirito area?

Expedia has 496 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.

If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.

Where can I learn more about changing or cancelling my trip to Santo Spirito?

To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page .

What can I see and do in this Florence neighborhood?

Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Piazza del Carmine are some other places worth a visit. A few places to visit in the area around Santo Spirito include Piazza di Santa Maria Novella, Santa Maria della Carmine, and Brancacci Chapel. When you're sightseeing in Florence, Il Nabucco di Matteo Gabellini and Teatro Comunale Florence are also worth a stop.

Top Santo Spirito Hotels

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Our top choices for Santo Spirito hotels

Panoramic Double Room, 1 Bedroom, Air conditioning, City View | Hypo-allergenic bedding, minibar, blackout drapes, soundproofing

SPIRIT OF FLORENCE Boutique Rooms

Santo Spirito

Christina

￥27,294 total

includes taxes & fees

Feb 26 - Feb 27

Royal Double Room | Minibar, in-room safe, soundproofing, free WiFi

Oltrarno Splendid

Santo Spirito

Maoying

￥28,962 total

includes taxes & fees

Feb 23 - Feb 24

AdAstra Suites

Santo Spirito

James

￥32,322 total

includes taxes & fees

Feb 25 - Feb 26

Double Room, Garden View | Pillowtop beds, minibar, in-room safe, desk

La Fonderia Firenze

Santo Spirito

Dan

￥19,648 total

includes taxes & fees

Feb 22 - Feb 23

Hotel Palazzo Guadagni

Santo Spirito

Ann

￥42,858 total

includes taxes & fees

Feb 25 - Feb 26

Superior Double Room, 1 King Bed | Premium bedding, down comforters, in-room safe, desk

La Torre Del Cestello

Santo Spirito

David

Ottantotto Firenze

Santo Spirito

Brook

￥36,135 total

includes taxes & fees

Mar 19 - Mar 20

Hotel Horto Convento

Santo Spirito

Gianmaria

￥21,489 total

includes taxes & fees

Feb 25 - Feb 26

Residenza D'Epoca Al Numero 8

Santo Spirito

Jacqueline

Palazzo D'Oltrarno - Residenza D'Epoca

Santo Spirito

Diane

￥22,127 total

includes taxes & fees

Mar 9 - Mar 10

Suite | Egyptian cotton sheets, premium bedding, in-room safe, desk

Palazzo Mannaioni Suites

Santo Spirito

Joseph

Foresteria Valdese di Firenze - Casa per Ferie

Santo Spirito

Roger

￥16,675 total

includes taxes & fees

Feb 22 - Feb 23

Soggiorno Alessandra

Santo Spirito

Elias

Standard Double or Twin Room, 1 Double or 2 Twin Beds, Private Bathroom | Down comforters, individually decorated, individually furnished, desk

1900 Artevita

Santo Spirito

Bianca

Hotel Firenze 2000

Santo Spirito

Josee

￥13,011 total

includes taxes & fees

Feb 24 - Feb 25

Comfort Condo, 4 Bedrooms | 1 bedroom, premium bedding, individually furnished, desk

Luxury Petra San Frediano by Mmega

Santo Spirito

"Very happy we booked here! It was such a pleasant place to stay!! Was happily surprised by a few things: The apartment is on the Piazza Carmine where there is a lovely old church Santa Maria del Carmine with the Brancacci Chapel. Also about a half block away and to left of the church steps there is a laundry mat, and just across the street from this a small grocery store, and a few more strides away a family bakery/kitchen where we got sandwiches, pastries and lasagna — lovely generational...

Anita

￥66,412 total

includes taxes & fees

Mar 3 - Mar 4

Torre di Bellosguardo

Santo Spirito

Brad

￥67,171 total

includes taxes & fees

Feb 22 - Feb 23

Casa Santo Nome di Gesù

Santo Spirito

Ning

Home in Florence

Santo Spirito

Paul

￥15,325 total

includes taxes & fees

Feb 25 - Feb 26

Family Apartment | Living area | 40-inch flat-screen TV with digital channels, TV

Appartamenti degli Artisti by Mmega

Santo Spirito

"We stayed here in November and had a wonderful experience. The location worked perfectly for my husband and I, close enough to the center to get everywhere easily, yet set in a quiet residential part of Florence where we could feel the local rhythm of the city. The staff who look after the house were all very easy to communicate with. The whole stay was smooth and comfortable. We truly enjoyed our time here!"

Ray

￥30,205 total

includes taxes & fees

Feb 23 - Feb 24

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Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito

Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

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Duomo

Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

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Ponte Vecchio showing a bridge and a river or creek

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

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Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

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Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

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