Find hotels in Santo Spirito, Florence from ￥22,404

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Discover 435 Santo Spirito hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Presidential Penthouse, 2 Bedrooms, Terrace, Tower | Terrace/patio
San Firenze Suites & Spa
4.0 star property
9.8 out of 10, Exceptional, (884)
"Great location. Wonderful staff. "
The price is ￥81,868
per night
May 27 - May 28
San Firenze Suites & Spa
Exterior
Portrait Firenze - Lungarno Collection
5.0 star property
9.8 out of 10, Exceptional, (276)
"I have already recommended this hotel to family and friends. This was our experience and we all missed it as soon we had to leave Florence : - welcome you receive at the door (no standard check in desk- instead you give staff your passports and they do their magic while you and your family enjoy delicious drinks in a very elegant and comfortable waiting room) - the staff anticipating your needs (we are not good planners and they booked for us both attractions and train tickets; suggested and...
The price is ￥252,854
per night
May 27 - May 28
Portrait Firenze - Lungarno Collection
Lobby
Grand Hotel Minerva
4.0 star property
9.6 out of 10, Exceptional, (884)
"Great hotel, will defiantly be going back, the staff were lovely and the location superb. We loved the art work around the hotel and the roof top pool, bar and view are amazing. "
The price is ￥114,320
per night
May 30 - May 31
Grand Hotel Minerva
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Reception
Bernini Palace
5.0 star property
9.6 out of 10, Exceptional, (1001)
"Beautiful hotel in the heart of historic Florence. The staff were welcoming and very attentive to our needs. Lovely continental breakfast was included. "
The price is ￥58,318
per night
May 22 - May 23
Bernini Palace
Suite, Terrace | View from room
The FRAME Hotel
4.0 star property
9.6 out of 10, Exceptional, (401)
"Great location. Walking distance from most of the top attractions of Florence. In 10 minutes or less, you can walk to the Duomo, the train station, the Mercato Centrale, or the Piazza della Repubblica. In about 15 minutes you can walk to the Galleria dell'Accademia, the Piazza della Signoria, Galleria degli Uffizi, or the Ponte Vecchio. The staff were friendly and attentive. We liked Daniel at the front desk. We stayed at the Gioconda suite, 269 sq ft, but it was split level, so the space...
The price is ￥61,056
per night
May 17 - May 18
The FRAME Hotel
Bar (on property)
Golden Tower Hotel & Spa
5.0 star property
9.6 out of 10, Exceptional, (837)
"Amazing staff! The hotel gave us an upgrade because we were traveling with a baby."
The price is ￥83,669
per night
Jun 5 - Jun 6
Golden Tower Hotel & Spa
Seasonal outdoor pool
Glance Hotel In Florence
4.0 star property
9.4 out of 10, Exceptional, (1002)
"It was a clean modern quiet room. Enjoyed the breakfast options. Great location for walking to sites and transportation etc. "
The price is ￥61,832
per night
May 22 - May 23
Glance Hotel In Florence
Superior Room, Non Smoking (stair access only) | Hypo-allergenic bedding, in-room safe, desk, blackout drapes
Il Perseo
3.0 star property
9.2 out of 10, Wonderful, (1001)
"This is a hidden gem that is walking distance to all the sites. Amazing staff and breakfast was good. Controlled entry, very safe. We highly recommend this hotel. "
The price is ￥37,972
per night
May 29 - May 30
Il Perseo
Bar (on property)
B&B Hotel Firenze Laurus al Duomo
4.0 star property
9.2 out of 10, Wonderful, (1001)
"I felt they went above and beyond to make us comfortable. I highly recommend them."
B&B Hotel Firenze Laurus al Duomo
Family Apartment, 3 Bedrooms, City View (Via del Corso 12) | City view
Firenze Rentals
9.2 out of 10, Wonderful, (315)
"The area at night was beautiful"
The price is ￥34,977
per night
May 29 - May 30
Firenze Rentals
Outdoor pool
The Social Hub Florence Lavagnini
4.0 star property
9.0 out of 10, Wonderful, (1003)
"Interesting & quirky, but easy atmosphere with all one needs for a nice stay. Be sure to check out the mercato central nearby for leather goods and upstairs food! Fantastic!"
The price is ￥31,237
per night
Jun 9 - Jun 10
The Social Hub Florence Lavagnini
Garden
Antica Dimora Sant'Anna
9.0 out of 10, Wonderful, (104)
"Very comfortable stay in a monastery. Basic single room. Double rooms have garden view and balcony and look great "
The price is ￥24,551
per night
May 19 - May 20
Antica Dimora Sant'Anna
Garden
Rivoli Boutique Hotel
4.0 star property
9.0 out of 10, Wonderful, (1000)
"Very beautiful nice to stay at"
The price is ￥49,161
per night
Jun 3 - Jun 4
Rivoli Boutique Hotel
Lobby
Hotel Hermitage
3.0 star property
9.0 out of 10, Wonderful, (958)
"Superb location, within walking distance of the Ponte Vecchio, Uffizi, Duomo, and all major tourist spots. In the heart of a hundred dining options and lovely staff with lots of suggestions."
The price is ￥47,076
per night
May 29 - May 30
Hotel Hermitage
Property entrance
Hotel Albani Firenze
4.0 star property
8.8 out of 10, Excellent, (1002)
"Great Hotel. Wonderful breakfast "
The price is ￥42,296
per night
Jun 6 - Jun 7
Hotel Albani Firenze
Property entrance
Allegroitalia San Gallo Firenze
4.0 star property
8.8 out of 10, Excellent, (1000)
"Room was amazingly big, and had a bottle of champagne in the room for us as a gift. The staff was super friendly. The hotel was beautiful and the lanscaping and courtyards were gorgeous. The hotel is walking distance to everything so we saved $$ on taxis. "
The price is ￥22,404
per night
Jun 10 - Jun 11
Allegroitalia San Gallo Firenze
Lobby
Sina Villa Medici, Autograph Collection
5.0 star property
8.6 out of 10, Excellent, (290)
"Super Hotel, Friendly Staff, Great Location "
The price is ￥107,850
per night
Jun 3 - Jun 4
Sina Villa Medici, Autograph Collection
Exterior
AC Hotel Firenze by Marriott
4.0 star property
8.6 out of 10, Excellent, (749)
"The hotel itself is beautiful and clean. Very modern. The staff in the lobby was very nice to us. But there was once employee who was significantly rude to us. It was 9 pm and I was getting ready to leave for dinner and somebody complained about me walking in heels inside the room. When the employee came to the room about the complaint he was extremely rude. "
The price is ￥42,855
per night
Jun 9 - Jun 10
AC Hotel Firenze by Marriott
Lobby
Starhotels Michelangelo
4.0 star property
8.6 out of 10, Excellent, (845)
"The staff was very nice and offered recommendations when checking in. The room was very clean, they also provided a hair dryer. Breakfast started at 6:30am, I thought the food was great. The location is very close to the train station by taxi, maybe a 20-25 minutes if walking. When leaving you can ask the front desk to call a taxi for you. I would definitely stay here again. "
The price is ￥39,997
per night
Jun 2 - Jun 3
Starhotels Michelangelo
Exterior
Le Stanze del Duomo
8.6 out of 10, Excellent, (453)
"Spectacular location near Duomo. Less than 10 minute walk to all major Florence attractions. Room was clean and comfortable. Strong WiFi. If you’re looking for a lot of space, this is not a good choice. If you’re like us and need only a good bed and hot shower, stay here. "
The price is ￥64,530
per night
Jun 4 - Jun 5
Le Stanze del Duomo
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Other neighborhoods around Santo Spirito

Hotels in top Florence neighborhoods Learn more about Santo Spirito
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

4 out of top 10 points of interest in this area
5/5(2,214 area reviews)

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Find hotels in Duomo

Santo Spirito hotels information

Number of reviews
14,746
Accommodation
435 hotels
Lowest Price
￥22,404
Highest Price
￥252,854

Frequently asked questions

What is Santo Spirito like?

Santo Spirito is a trendy neighborhood known for its beautiful river views. Looking for sights you might find in a travel guide about Santo Spirito? Consider a visit to Historic Center - Downtown while you're in the neighborhood.

What's the best accommodation in Santo Spirito?

Based on Expedia customer reviews, AdAstra Suites is the highest ranked property in Santo Spirito. This B&B is a short 1-minute walk from Pitti Palace, and it offers free breakfast and free WiFi. Other favorite options in the area include Oltrarno Splendid and Ottantotto Firenze.

How many hotels can I expect to find in the Santo Spirito area?

Expedia has 432 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater San Frediano area.

If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.

Where can I learn more about changing or cancelling my trip to Santo Spirito?

To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.

What can I see and do in this San Frediano neighborhood?

Historic Center - Downtown, Porta Romana, and Pitti Palace are some local landmarks to explore in Santo Spirito. As you're discovering the neighborhood, Piazza Santo Spirito and Arno River are some other places worth a visit. Favorite places to visit in the surrounding area include Piazza di Santa Maria Novella, Uffizi Gallery, and Cathedral of Santa Maria del Fiore. When you're sightseeing in San Frediano, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.

Recent reviews of Santo Spirito hotels

Ottantotto Firenze

Ottantotto Firenze

5/5 Excellent
"wonderful"
A verified traveler stayed at Ottantotto Firenze
Posted 6 days ago
Ottantotto Firenze