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Apr 11 - Apr 12
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Our top choices for Santo Spirito hotels

Apartment | Laptop workspace, iron/ironing board, cribs/infant beds, free WiFi

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
9.4 out of 10, Exceptional, (3 reviews)
"Very nice apartment and great location. The included parking and laundry facilities were the reason we selected the property, and were very happy with everything. Overall a lovely stay. "
United States
Michele
The price is ￥21,159
￥42,252 total
includes taxes & fees
Apr 22 - Apr 23
Mamo Florence - Bice & Krizia Apartments
Property entrance

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (202 reviews)
"The room was clean a d comfortable, and the staff was very courteous and helpful. The location was also good with most attractions being a 30 to 40 minute walk or less."
United States
Roger
The price is ￥17,084
￥21,025 total
includes taxes & fees
May 11 - May 12
Foresteria Valdese di Firenze - Casa per Ferie
Standard Double or Twin Room, 1 Double or 2 Twin Beds, Private Bathroom | Down comforters, individually decorated, individually furnished, desk

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (180 reviews)
"Our stay here was wonderful! The host was so pleasant and the view from the terrace was beautiful. The location was in a great spot for enjoying the Florentine neighborhoods, and close to many of the restaurants recommended to us. We would stay here again in a heartbeat."
United States
Bianca
The price is ￥20,170
￥24,428 total
includes taxes & fees
Apr 12 - Apr 13
1900 Artevita
Double Room, Garden View | Pillowtop beds, minibar, in-room safe, desk

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (177 reviews)
"The room was beautiful and clean, the staff was pleasant, breakfast was fantastic, 10/10"
United States
Dan
The price is ￥24,969
￥29,706 total
includes taxes & fees
Apr 27 - Apr 28
La Fonderia Firenze
Exterior

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
9.0 out of 10, Wonderful, (22 reviews)
"Very goord place to stay"
United States
Victor
The price is ￥14,299
￥17,970 total
includes taxes & fees
Apr 12 - Apr 13
L'Antica Porta Boutique B&B
Deluxe Quadruple Room | Hypo-allergenic bedding, minibar, in-room safe, free WiFi

Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.4 out of 10, Good, (93 reviews)
"Great service easy check in Clean safe quiet "
United States
Gabriel
The price is ￥15,021
￥18,764 total
includes taxes & fees
Apr 27 - Apr 28
Palazzo Oliveto
Fireplace

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (170 reviews)
"Great location and extremely charming!"
United States
Brook
The price is ￥36,410
￥42,665 total
includes taxes & fees
Apr 12 - Apr 13
Ottantotto Firenze
Family Apartment | Living area | 40-inch flat-screen TV with digital channels, TV

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.4 out of 10, Very Good, (33 reviews)
"Nice location with easy access to bus stops. Close to good restaurants and bars. "
United States
Prasanna
The price is ￥17,798
￥36,756 total
includes taxes & fees
Apr 27 - Apr 28
Appartamenti degli Artisti by Mmega
Property entrance

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (148 reviews)
"Excellent location and very friendly staff."
Canada
Scott
The price is ￥21,956
￥26,765 total
includes taxes & fees
Apr 12 - Apr 13
Residenza D'Epoca Al Numero 8
Courtyard

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (141 reviews)
"Claudia was a great hostess who greeted us at the door and explained the room and comings and goings. She was gracious to hold our luggage on our last day before departing by train. "
United States
Anita
The price is ￥17,057
￥23,244 total
includes taxes & fees
Apr 12 - Apr 13
Drom Florence Rooms & Apartments
Apartment | Living area | 24-inch flat-screen TV with digital channels

Mamo Florence - Turandot Apartment

Mamo Florence - Turandot Apartment
Santo Spirito
10.0 out of 10, Exceptional, (1 review)
"L'appartement est très bien situé, confortable et calme. Seul bémol, le wifi pas performant."
France
Bertrand
The price is ￥22,458
￥45,542 total
includes taxes & fees
Apr 23 - Apr 24
Mamo Florence - Turandot Apartment
Front of property

Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (194 reviews)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is ￥13,390
￥16,409 total
includes taxes & fees
Apr 12 - Apr 13
Hotel Firenze 2000
Superior Double Room, 1 King Bed | Premium bedding, down comforters, in-room safe, desk

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.2 out of 10, Wonderful, (248 reviews)
"It was in a great location, we had an excellent view from our room."
United States
Tonya
The price is ￥22,387
￥27,240 total
includes taxes & fees
Apr 12 - Apr 13
La Torre Del Cestello
Front of property

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.6 out of 10, Exceptional, (48 reviews)
"Excellent place to stay!"
United States
Diane
The price is ￥30,680
￥35,989 total
includes taxes & fees
Apr 15 - Apr 16
Palazzo D'Oltrarno - Residenza D'Epoca
Lobby sitting area

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (226 reviews)
"Gorgeous room in a beautiful property, very helpful staff, tranquil setting"
United Kingdom
Olivia
The price is ￥58,982
￥67,485 total
includes taxes & fees
Apr 23 - Apr 24
AdAstra Suites
Food court

Home in Florence

Home in Florence
Santo Spirito
9.0 out of 10, Wonderful, (72 reviews)
"Lovely room and the people running the place were friendly and efficient "
United Kingdom
Thomas
The price is ￥20,575
￥24,873 total
includes taxes & fees
Apr 15 - Apr 16
Home in Florence
Comfort Apartment, 1 Bedroom | 1 bedroom, premium bedding, down comforters, individually decorated

Santo Spirito Bright Flat by Mmega

Santo Spirito Bright Flat by Mmega
Santo Spirito
8.0 out of 10, Very Good, (1 review)
"The room was very clean overall, with plenty of room. Very close to main attractions and train station. Only downside was that heaters did not work well, toilet seat was broken and never fixed and there was only one fork available. Other than that, I would recommend for the price."
United States
frank
The price is ￥17,734
￥36,625 total
includes taxes & fees
Apr 23 - Apr 24
Santo Spirito Bright Flat by Mmega
Panoramic Double Room, 1 Bedroom, Air conditioning, City View | Hypo-allergenic bedding, minibar, blackout drapes, soundproofing

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"Great place to stay for our visit to Florence. Walking distance to everything but in quiet neighborhood. Staff are very friendly and helpful. "
United States
Wendy
The price is ￥36,053
￥41,899 total
includes taxes & fees
Apr 19 - Apr 20
SPIRIT OF FLORENCE Boutique Rooms
Interior

Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (346 reviews)
"Really a nice place, like the room style and good for family stay!"
United States
Ning
The price is ￥27,176
￥32,126 total
includes taxes & fees
Apr 19 - Apr 20
Casa Santo Nome di Gesù
Suite | Room amenity

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is ￥90,792
￥102,476 total
includes taxes & fees
Apr 18 - Apr 19
Torre di Bellosguardo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

1900 Artevita

1900 Artevita

8/10 Good
"Huge room on the outskirts of the city centre. Lovely area with great restaurants. The room was exceptionally clean, the downside was the very hard bed as we prefer a softer bed. We would definitely come back here if we returned to Florence."
Gillian 4-night trip
Posted 1 day ago
1900 Artevita

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on our traveler data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighborhood include Palazzo Mannaioni Suites and La Torre Del Cestello.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 497 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Piazza di Santa Maria Novella and Cathedral of Santa Maria del Fiore are some favorite places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.

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