Santo Spirito Vacations from ￥382,511

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The Latest Santo Spirito Vacation Packages

Price found within the past 48 hours. Click for updated prices.
c-hotels Club

c-hotels Club

4 out of 5
Historic Centre of Florence
Price was ￥442,044, price is now ￥382,511 per person
￥382,511
per person
Sep 18 - Sep 22
found 1 hour ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
8.4/10 Very Good! (1,004 reviews)
Blood on the bed sheets and mold in the shower. This is a place I’d stay away from. CHotels Joy is just a few blocks away and great. We had a much better stay there.

Reviewed on Jun 29, 2026

Hotel La Scaletta Al Ponte Vecchio

Hotel La Scaletta Al Ponte Vecchio

4 out of 5
Historic Centre of Florence
Price was ￥550,893, price is now ￥434,418 per person
￥434,418
per person
Sep 18 - Sep 22
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
8.8/10 Excellent! (1,002 reviews)
Great stay overall especially in the courtyard

Reviewed on Jul 7, 2026

c-hotels Ambasciatori

c-hotels Ambasciatori

4 out of 5
Historic Centre of Florence
Price was ￥486,164, price is now ￥420,236 per person
￥420,236
per person
Sep 18 - Sep 22
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
8.2/10 Very Good! (1,004 reviews)
The staff, specially Adrian was professional and friendly. Near the train station and fairly close. To the city center 17 minutes. Area at night it was quite empty. But hotel wise it was excellent.

Reviewed on Jul 9, 2026

Hotel Garibaldi Blu

Hotel Garibaldi Blu

4 out of 5
Historic Centre of Florence
Price was ￥526,585, price is now ￥456,138 per person
￥456,138
per person
Sep 18 - Sep 22
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
9.2/10 Wonderful! (884 reviews)
The air conditioning didn’t seem to be working consistently, our room was a bit hot. The breakfast was perfect and a great way to start our day. The location was excellent for ask the areas of Florence we wanted try see. We would highly recommend this place.

Reviewed on Jul 5, 2026

Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA

5 out of 5
Historic Centre of Florence
Price was ￥512,774, price is now ￥449,172 per person
￥449,172
per person
Sep 18 - Sep 22
found 1 hour ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
9.2/10 Wonderful! (66 reviews)
Lovely hotel, very friendly staff and great location just outside hustle and bustle of Florence.

Reviewed on Apr 21, 2026

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
A river with buildings on the right bank.

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundableReserve now, pay when you stay
The price is ￥23,748 per night from Aug 10 to Aug 11
￥23,748
￥28,722 total
Aug 10 - Aug 11
includes taxes & fees
9.8/10 Exceptional! (686 reviews)
"Beautiful, clean, amazing breakfast, really nice staff. 10/10 recommendation"

Reviewed on Jul 7, 2026

Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
Fully refundableReserve now, pay when you stay
The price is ￥21,037 per night from Jul 26 to Jul 27
￥21,037
￥25,740 total
Jul 26 - Jul 27
includes taxes & fees
9/10 Wonderful! (275 reviews)
"Great location! Just across the river, slightly away from the more touristy area, but still walkable from the train station. Roxy at reception was lovely. They had us wait just 10 minutes & we were allowed to check in early. The room was fabulous! So much space! The air conditioning rocked! Free ..."

Reviewed on Jul 9, 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
Fully refundableReserve now, pay when you stay
The price is ￥14,586 per night from Aug 2 to Aug 3
￥14,586
￥18,644 total
Aug 2 - Aug 3
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"

Reviewed on May 12, 2026

UNA Hotels Vittoria Firenze
See all 514 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Spirito vacation package cost?
From just ￥382,511. Yes, you read that right. Our Santo Spirito packages are the best way to make your dollar go further. Bundle your favorite hotels, flights and rental car and explore this wonderful destination.
How do I get a cheap travel package to Santo Spirito?
If you love scoring a bargain, bundle your bookings into a Santo Spirito vacation package. Whether you need hotels, flights, activities or rental cars, you can book everything in one place. You'll have endless choice at your fingertips as well. Expedia has more than 550 partner airlines and 1,000,000 hotels across the globe to choose from. Fly with who you want, stay in a place you like and save precious dollars — now that's the ideal getaway!
What are the top hotels in Santo Spirito?
Reserve a room at Sweet Home Campuccio, 2 Double Bedrooms In San Frediano. It's one of this area's most sought-after hotels. Another well-known option in Santo Spirito is Residenza Oltrarno, An Elegant Apartment In The Historic Center Of Florence.
How far in advance should I book my Santo Spirito vacation?
To score cheap prices, book as soon as you can. Airlines typically release tickets, along with some of the lowest fares, up to a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Santo Spirito, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Santo Spirito travel package include?
Rental cars, flights and hotels, or any combination of the three — it's totally up to you. Whether you're headed to Santo Spirito with the entire family or enjoying a solo break, there's a bundle to match every budget and style. Once you've made your booking, why not add on a couple of tours as well?
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your trip together is one of the best ways to save. Combine car rentals, airfares and hotels into a neat little package. But you're not restricted to hotels. Expedia features all sorts of properties, including vacation rentals like oceanfront condos and city residences. The list goes on!
Can I choose my airline with a Santo Spirito Expedia vacation package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our vacation packages give you the freedom to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Santo Spirito vacation package?
If your vacation plans in Santo Spirito have been upended, it's a relief to know that it is possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. For more details, check our Customer Service Portal.

Stay near popular Santo Spirito attractions

A town square with historic buildings, a church, and a bell tower.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
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Things to do

Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

￥6,491
per adult
88% of travellers recommend
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Small-Group Wine Tasting Experience in the Tuscan Countryside

Small-Group Wine Tasting Experience in the Tuscan Countryside

￥16,553
per adult
98% of travellers recommend
Small-Group Wine Tasting Experience in the Tuscan Countryside
Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

￥2,976
per adult
94% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.