Santo Spirito Vacations from ￥312,360

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The Latest Santo Spirito Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Accademia

Hotel Accademia

3 out of 5
Historic Centre of Florence
Price was ￥318,513, price is now ￥312,360 per person
￥312,360
per person
Dec 26 - Dec 29
found 1 hour ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
9.2/10 Wonderful! (731 reviews)
Clean room, excellent staff, no AC due to season, excellent location with many shops and restaurants. Walkable to major sites.

Reviewed on Oct 29, 2025

Plaza Hotel Lucchesi

Plaza Hotel Lucchesi

4 out of 5
Historic Centre of Florence
Price was ￥366,224, price is now ￥333,257 per person
￥333,257
per person
Dec 26 - Dec 29
found 1 hour ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
9.4/10 Exceptional! (999 reviews)
Wonderful hotel. Incredible views from the huge rooftop bar/pool deck. Wonderful breakfast buffet with many hot and cold options. Main level bar is beautiful and the seating areas are both well-appointed and comfortable. Both bars offer gratis snacks. View of the river Arno, Piazza el Michelangelo and more from our room window were stunning. You can literally walk almost anywhere in the city from this location.

Reviewed on Oct 18, 2025

LHP River Club

LHP River Club

5 out of 5
Santa Croce
Price was ￥348,220, price is now ￥333,588 per person
￥333,588
per person
Dec 26 - Dec 29
found 1 hour ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
9/10 Wonderful! (12 reviews)
Amazing time spent here. The rooms are huge ! And the sparkling wine was a very nice gesture. Bed is comfortable and continently located near the huge bathroom. No delays with checking in. Very close to the city center. Very friendly and welcoming front desk attendant! You will always find free parking on the street so don’t need to use the 35$ per night garage !

Reviewed on Oct 22, 2025

Solo Experience Hotel

Solo Experience Hotel

4 out of 5
Historic Centre of Florence
Price was ￥329,795, price is now ￥317,890 per person
￥317,890
per person
Dec 26 - Dec 29
found 1 hour ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
9.4/10 Exceptional! (906 reviews)
Clean, surprisingly spacious room and bath. Easy access to all of the sites and restaurants. Friendly staff! Would definitely recommend.

Reviewed on Oct 31, 2025

B&B Hotel Firenze Laurus al Duomo

B&B Hotel Firenze Laurus al Duomo

4 out of 5
Historic Centre of Florence
Price was ￥320,336, price is now ￥320,336 per person
￥320,336
per person
Dec 26 - Dec 29
found 1 hour ago
Roundtrip flight included
Tokyo (TYO) to Florence (FLR)
9.2/10 Wonderful! (1,003 reviews)
It’s only a short walk from the main Santa Maria Novella terminus, so reduced my stress about train, tram and bus times. Staff were super friendly and welcoming, always smiling and happy to help with anything. The rooms were beautiful, well stocked, clean, bright and big! Great views from all 3 rooms we booked. The late checkout (12pm) was a game changer in terms of maximising our final morning in Florence.

Reviewed on Oct 16, 2025

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
The price is ￥16,600 per night from Dec 1 to Dec 2
￥16,600
￥20,747 total
Dec 1 - Dec 2
includes taxes & fees
9.6/10 Exceptional! (584 reviews)
An oasis of calm - it is not buzzy and over the top like many places in the tourist center. Instead, it is tranquil, in a good area within easy walking distance to most of what you want to see. We enjoyed our stay.

Reviewed on Oct 25, 2025

Hotel Horto Convento
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
The price is ￥21,964 per night from Nov 14 to Nov 15
￥21,964
￥26,647 total
Nov 14 - Nov 15
includes taxes & fees
8.4/10 Very Good! (988 reviews)
Amazing place, love the decor!

Reviewed on Jul 28, 2025

UNA Hotels Vittoria Firenze
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r, Florence, FI
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (1,042 reviews)
The place was clean and located in the heart Florence most memorable attractions..

Reviewed on Oct 29, 2025

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Palazzo Mannaioni Suites
See all 474 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Spirito vacation package cost?
From just ￥312,360. Yes, you read that right. Our Santo Spirito packages are the best way to make your dollar go further. Bundle your favorite hotels, flights and rental car and explore this wonderful destination.
How do I get a cheap travel package to Santo Spirito?
If you love scoring a bargain, bundle your bookings into a Santo Spirito vacation package. Whether you need hotels, flights, activities or rental cars, you can book everything in one place. You'll have endless choice at your fingertips as well. Expedia has more than 550 partner airlines and 1,000,000 hotels across the globe to choose from. Fly with who you want, stay in a place you like and save precious dollars — now that's the ideal getaway!
What are the top hotels in Santo Spirito?
Reserve a room at Sweet Home Campuccio, 2 Double Bedrooms In San Frediano. It's one of this area's most sought-after hotels. Another well-known option in Santo Spirito is Residenza Oltrarno, An Elegant Apartment In The Historic Center Of Florence.
How far in advance should I book my Santo Spirito vacation?
To score cheap prices, book as soon as you can. Airlines typically release tickets, along with some of the lowest fares, up to a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Santo Spirito, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Santo Spirito travel package include?
Rental cars, flights and hotels, or any combination of the three — it's totally up to you. Whether you're headed to Santo Spirito with the entire family or enjoying a solo break, there's a bundle to match every budget and style. Once you've made your booking, why not add on a couple of tours as well?
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your trip together is one of the best ways to save. Combine car rentals, airfares and hotels into a neat little package. But you're not restricted to hotels. Expedia features all sorts of properties, including vacation rentals like oceanfront condos and city residences. The list goes on!
Can I choose my airline with a Santo Spirito Expedia vacation package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our vacation packages give you the freedom to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Santo Spirito vacation package?
If your vacation plans in Santo Spirito have been upended, it's a relief to know that it is possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. For more details, check our Customer Service Portal.

Things to do

Florence Accademia Gallery Tour with Entrance Ticket Included

Florence Accademia Gallery Tour with Entrance Ticket Included

￥6,688
per adult
90% of travellers recommend
Florence Accademia Gallery Tour with Entrance Ticket Included
Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

￥3,717
per adult
78% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Excursion to Pisa through the Tuscan Countryside

Excursion from Florence to Pisa through the Tuscan Countryside

￥10,443
per adult
88% of travellers recommend
Excursion from Florence to Pisa through the Tuscan Countryside
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.