Santo Spirito Vacations from ￥164,676

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The Latest Santo Spirito Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

4 out of 5
San Lorenzo
Price was ￥270,818, price is now ￥164,676 per person
￥164,676
per person
Apr 6 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Florence (FLR)
9/10 Wonderful! (1,261 reviews)
Comfortable beds, incredible friendly staff. Great food in the restaurant and lovely rooftop bar and pool!

Reviewed on Feb 15, 2026

The Hoxton Florence

The Hoxton Florence

4 out of 5
Historic Centre of Florence
Price was ￥289,750, price is now ￥175,227 per person
￥175,227
per person
Apr 6 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Florence (FLR)
9.4/10 Exceptional! (147 reviews)
Spacious room. Great location. Beautiful restaurant & courtyard.

Reviewed on Feb 9, 2026

Bernini Palace

Bernini Palace

5 out of 5
Historic Centre of Florence
Price was ￥308,439, price is now ￥191,948 per person
￥191,948
per person
Apr 6 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Florence (FLR)
9.6/10 Exceptional! (1,007 reviews)
From the time we entered the hotel, the staff, lobby, the room were exceptional. The location of the hotel was great, close to everything. I would absolutely recommend this hotel to anyone visiting Florence.

Reviewed on Feb 20, 2026

25hours Hotel Florence Piazza San Paolino

25hours Hotel Florence Piazza San Paolino

4 out of 5
Historic Centre of Florence
Price was ￥281,098, price is now ￥179,029 per person
￥179,029
per person
Apr 6 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Florence (FLR)
9.4/10 Exceptional! (927 reviews)
Very detailed decor and very clean!

Reviewed on Jan 5, 2026

The FRAME Hotel

The FRAME Hotel

4 out of 5
Historic Centre of Florence
Price was ￥279,813, price is now ￥181,458 per person
￥181,458
per person
Apr 6 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Florence (FLR)
9.6/10 Exceptional! (586 reviews)
Everything was excellent. Staff was friendly, helpful and very knowledgeable. Room was clean and well equipped. Location was wonderful, a few blocks from pretty much everything. Next time in Florence we will stay again at The Frame.

Reviewed on Feb 10, 2026

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundableReserve now, pay when you stay
The price is ￥17,430 per night from Feb 25 to Feb 26
￥17,430
￥21,731 total
Feb 25 - Feb 26
includes taxes & fees
9.6/10 Exceptional! (621 reviews)
Lovely location, staff were great

Reviewed on Feb 13, 2026

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (1,068 reviews)
Very helpful at the front desk. Check in was seamless - very attentive staff to all of our needs :)

Reviewed on Feb 5, 2026

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Palazzo Mannaioni Suites
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
Fully refundableReserve now, pay when you stay
The price is ￥15,671 per night from Feb 22 to Feb 23
￥15,671
￥19,796 total
Feb 22 - Feb 23
includes taxes & fees
8.4/10 Very Good! (987 reviews)
Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back!

Reviewed on Jan 1, 2026

UNA Hotels Vittoria Firenze
See all 494 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Spirito vacation package cost?
From just ￥164,676. Yes, you read that right. Our Santo Spirito packages are the best way to make your dollar go further. Bundle your favorite hotels, flights and rental car and explore this wonderful destination.
How do I get a cheap travel package to Santo Spirito?
If you love scoring a bargain, bundle your bookings into a Santo Spirito vacation package. Whether you need hotels, flights, activities or rental cars, you can book everything in one place. You'll have endless choice at your fingertips as well. Expedia has more than 550 partner airlines and 1,000,000 hotels across the globe to choose from. Fly with who you want, stay in a place you like and save precious dollars — now that's the ideal getaway!
What are the top hotels in Santo Spirito?
Reserve a room at Sweet Home Campuccio, 2 Double Bedrooms In San Frediano. It's one of this area's most sought-after hotels. Another well-known option in Santo Spirito is Residenza Oltrarno, An Elegant Apartment In The Historic Center Of Florence.
How far in advance should I book my Santo Spirito vacation?
To score cheap prices, book as soon as you can. Airlines typically release tickets, along with some of the lowest fares, up to a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Santo Spirito, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Santo Spirito travel package include?
Rental cars, flights and hotels, or any combination of the three — it's totally up to you. Whether you're headed to Santo Spirito with the entire family or enjoying a solo break, there's a bundle to match every budget and style. Once you've made your booking, why not add on a couple of tours as well?
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your trip together is one of the best ways to save. Combine car rentals, airfares and hotels into a neat little package. But you're not restricted to hotels. Expedia features all sorts of properties, including vacation rentals like oceanfront condos and city residences. The list goes on!
Can I choose my airline with a Santo Spirito Expedia vacation package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our vacation packages give you the freedom to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Santo Spirito vacation package?
If your vacation plans in Santo Spirito have been upended, it's a relief to know that it is possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. For more details, check our Customer Service Portal.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.