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Check availability on Santa Maria Novella Luxury Hotels

Our top choices for Santa Maria Novella luxury hotels

Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool umbrellas
Grand Hotel Minerva

Grand Hotel Minerva

Grand Hotel Minerva
4.0 star property
Historic Centre of Florence
9.6 out of 10, Exceptional, (1000)
"Great breakfast and spacious rooms"
United States
James
The price is ￥48,224
￥55,607 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Grand Hotel Minerva
Signature Suite, 1 Bedroom, Terrace (Balcony) | Premium bedding, minibar, in-room safe, desk
Sina Villa Medici, Autograph Collection

Sina Villa Medici, Autograph Collection

Sina Villa Medici, Autograph Collection
5.0 star property
Historic Centre of Florence
8.6 out of 10, Excellent, (309)
"Staff was very helpful despite the hot weather. Great stay, very serene environment for vacation."
United States
Chi
The price is ￥39,776
￥46,681 total
includes taxes & fees
Dec 21 - Dec 22
Sina Villa Medici, Autograph Collection
Restaurant
The Excelsior, a Luxury Collection Hotel, Florence

The Excelsior, a Luxury Collection Hotel, Florence

The Excelsior, a Luxury Collection Hotel, Florence
5.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (359)
"Exemplary staff! Amazing! Stunningly beautiful hotel! Fabulous views! "
United Kingdom
Helen Mary
The price is ￥89,440
￥101,299 total
includes taxes & fees
Dec 20 - Dec 21
The Excelsior, a Luxury Collection Hotel, Florence
Massages
Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA
5.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (59)
"Property is beautiful and quiet. Would stay there again. "
United States
Chad
The price is ￥39,716
￥46,602 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Dimora Palanca Boutique & SPA
Terrace/patio
Hotel L'Orologio Firenze

Hotel L'Orologio Firenze

Hotel L'Orologio Firenze
4.0 star property
Historic Centre of Florence
9.6 out of 10, Exceptional, (1001)
"Location, staff and breakfast were excellent"
United States
paula
The price is ￥33,258
￥39,145 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hotel L'Orologio Firenze
Royal Suite, 1 King Bed, Balcony, River View | Living room | Flat-screen TV, DVD player
The St. Regis Florence

The St. Regis Florence

The St. Regis Florence
5.0 star property
Historic Centre of Florence
9.6 out of 10, Exceptional, (264)
"Our stay was amazing, the room was great and the staff was fantastic! "
United States
Anonymous traveler
The price is ￥104,347
￥117,697 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The St. Regis Florence
View from property
Hotel Santa Maria Novella

Hotel Santa Maria Novella

Hotel Santa Maria Novella
4.0 star property
Historic Centre of Florence
9.6 out of 10, Exceptional, (1002)
"Excellent hotel"
United States
Edward
The price is ￥34,782
￥40,812 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hotel Santa Maria Novella
Courtyard
Palazzo Montebello

Palazzo Montebello

Palazzo Montebello
4.0 star property
Historic Centre of Florence
9.2 out of 10, Wonderful, (1003)
"Hotel is beautiful, staff was kind, room was so lovely!"
United States
Jill
The price is ￥27,826
￥33,159 total
includes taxes & fees
Dec 19 - Dec 20
Palazzo Montebello
View from property
AC Hotel Firenze by Marriott

AC Hotel Firenze by Marriott

AC Hotel Firenze by Marriott
4.0 star property
Santa Maria Novella
8.6 out of 10, Excellent, (781)
"Hotel is nice, amenities are reasonable. Not the best location but reasonable for a transit hotel."
United States
Mohan
The price is ￥23,794
￥28,725 total
includes taxes & fees
Jan 10 - Jan 11, 2026
AC Hotel Firenze by Marriott
Local cuisine
25hours Hotel Florence Piazza San Paolino

25hours Hotel Florence Piazza San Paolino

25hours Hotel Florence Piazza San Paolino
4.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (947)
"so in love with this hotel, after walking all day long, to come home to such a genuinely cute environment felt great. "
United States
Alexia
The price is ￥25,341
￥30,426 total
includes taxes & fees
Jan 6 - Jan 7, 2026
25hours Hotel Florence Piazza San Paolino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Price trends for hotels in Santa Maria Novella

Less expensive
More expensive
Next month
February
June
￥21,087
Month
Price
January
￥21,087
February
￥20,541
March
￥24,180
April
￥35,927
May
￥40,483
June
￥41,002
July
￥32,436
August
￥24,781
September
￥39,917
October
￥39,194
November
￥24,574
December
￥22,029
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Santa Maria Novella.

Top Santa Maria Novella Hotel Reviews

Hotel Albani Firenze

Hotel Albani Firenze

10/10 Excellent
"Friendly staff and rooms were good"
ALMA 1-night trip
Posted 6 days ago
Hotel Albani Firenze

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Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Santa Maria Novella?
Travel to Florence Airport, Peretola (FLR) Airport and then treat yourself to a stay at one of 7 Santa Maria Novella luxury hotels. During your visit, you might want to enjoy the art and shopping which Santa Maria Novella is known for.
What's the best luxury place to stay in Santa Maria Novella?
The St. Regis Florence is a luxury hotel with spa services and in-room massages, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Anglo American Hotel Florence, Curio Collection by Hilton and Sina Villa Medici, Autograph Collection are two other upscale options for your trip.
How many luxury hotels are there in Santa Maria Novella?
Lie in the lap of luxury during your getaway to Santa Maria Novella in one of Expedia's 7 luxury hotels.
What's there to see and do in Santa Maria Novella?
When you're in Santa Maria Novella, enjoy exploring the sights and attractions here including The New Florence Opera House, Palazzo dei Congressi, and Fortezza da Basso. If you have a little extra time during your trip, you might want to check out Basilica of Santa Maria Novella and Via Faenza.
How can I get around Santa Maria Novella?
It's easier to get around town comfortably when you know your options. Nearby metro stations include Porta al Prato - Leopolda Tram Stop, Fratelli Rosselli Tram Stop, and Belfiore Tram Stop.