Find hotels in Illinois Medical District, Chicago from ￥22,310

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Sep 29 - Sep 30
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Oct 3 - Oct 5
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Discover 4,593 Illinois Medical District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hyatt House Chicago Medical/University District
Exterior

Hyatt House Chicago Medical/University District

3.5 star property
9.0 out of 10, Wonderful, (1139)
"Good place to stay "
The price is ￥30,795
￥36,150 total
includes taxes & fees
Oct 6 - Oct 7
Hyatt House Chicago Medical/University District
Hampton Inn & Suites Chicago Medical District UIC
Business center

Hampton Inn & Suites Chicago Medical District UIC

2.5 star property
9.6 out of 10, Exceptional, (262)
"Altogether a solid stay!"
The price is ￥24,995
￥29,343 total
includes taxes & fees
Oct 5 - Oct 6
Hampton Inn & Suites Chicago Medical District UIC
Hyatt Place Chicago Medical/University District
Lobby

Hyatt Place Chicago Medical/University District

3.0 star property
9.0 out of 10, Wonderful, (1349)
"Great place to stay!"
The price is ￥32,140
￥37,730 total
includes taxes & fees
Oct 6 - Oct 7
Hyatt Place Chicago Medical/University District
Eurostars Magnificent Mile
Reception

Eurostars Magnificent Mile

4.0 star property
8.8 out of 10, Excellent, (3082)
"Perfect location, walkable to many restaurants and shops"
The price is ￥27,985
￥32,852 total
includes taxes & fees
Oct 29 - Oct 30
Eurostars Magnificent Mile
DoubleTree by Hilton Chicago - Magnificent Mile
Outdoor pool, cabanas (surcharge), pool umbrellas

DoubleTree by Hilton Chicago - Magnificent Mile

4.0 star property
8.8 out of 10, Excellent, (2089)
"Great location and very nice staff!!"
The price is ￥27,387
￥32,150 total
includes taxes & fees
Oct 19 - Oct 20
DoubleTree by Hilton Chicago - Magnificent Mile
Sable at Navy Pier Chicago, Curio Collection by Hilton
Terrace/patio

Sable at Navy Pier Chicago, Curio Collection by Hilton

4.0 star property
9.4 out of 10, Exceptional, (2181)
"Great hotel "
The price is ￥28,582
￥37,887 total
includes taxes & fees
Oct 19 - Oct 20
Sable at Navy Pier Chicago, Curio Collection by Hilton
River Hotel
Reception

River Hotel

4.0 star property
8.8 out of 10, Excellent, (4724)
"Staff friendly and helpful..and accommodations just right..great location! "
The price is ￥29,001
￥34,045 total
includes taxes & fees
Oct 5 - Oct 6
River Hotel
Aloft Chicago Mag Mile
Cocktail bar

Aloft Chicago Mag Mile

3.0 star property
8.6 out of 10, Excellent, (2863)
"Had a great stay!"
The price is ￥24,068
￥28,253 total
includes taxes & fees
Oct 5 - Oct 6
Aloft Chicago Mag Mile
Hilton Chicago/Magnificent Mile Suites
Ballroom

Hilton Chicago/Magnificent Mile Suites

3.5 star property
8.8 out of 10, Excellent, (3020)
"Enjoyed our stay"
The price is ￥24,016
￥28,194 total
includes taxes & fees
Oct 20 - Oct 21
Hilton Chicago/Magnificent Mile Suites
Hilton Garden Inn Chicago Downtown/Magnificent Mile
Exterior

Hilton Garden Inn Chicago Downtown/Magnificent Mile

3.0 star property
8.4 out of 10, Very Good, (4018)
"Excellent central location and local dining options. "
The price is ￥27,964
￥32,827 total
includes taxes & fees
Oct 1 - Oct 2
Hilton Garden Inn Chicago Downtown/Magnificent Mile
citizenM Chicago Downtown
Terrace/patio

citizenM Chicago Downtown

4.0 star property
9.4 out of 10, Exceptional, (3895)
"Absolutely loved this hotel and location. "
The price is ￥30,368
￥35,650 total
includes taxes & fees
Oct 30 - Oct 31
citizenM Chicago Downtown
Freehand Chicago
Cocktail bar

Freehand Chicago

4.0 star property
8.0 out of 10, Very Good, (2408)
"Location was excellent would stay there again"
The price is ￥13,025
￥22,310 total
includes taxes & fees
Oct 27 - Oct 28
Freehand Chicago
Congress Plaza Hotel
Banquet hall

Congress Plaza Hotel

3.5 star property
8.0 out of 10, Very Good, (9367)
"The staff was top notch, the bed so comfortable, just a great overall stay"
The price is ￥20,081
￥23,573 total
includes taxes & fees
Oct 26 - Oct 27
Congress Plaza Hotel
Hilton Chicago
Exterior

Hilton Chicago

4.0 star property
8.4 out of 10, Very Good, (2227)
"Very nice hotel "
The price is ￥27,494
￥36,663 total
includes taxes & fees
Oct 23 - Oct 24
Hilton Chicago
FOUND Hotel Chicago River North
Exterior

FOUND Hotel Chicago River North

2.0 star property
8.2 out of 10, Very Good, (260)
"Lovely hotel."
The price is ￥15,691
￥18,419 total
includes taxes & fees
Oct 1 - Oct 2
FOUND Hotel Chicago River North
Best Western River North Hotel
Rooftop terrace

Best Western River North Hotel

2.5 star property
7.8 out of 10, Good, (1044)
"It was a great stay"
The price is ￥22,745
￥26,700 total
includes taxes & fees
Oct 2 - Oct 3
Best Western River North Hotel
Hotel Riu Plaza Chicago
Front of property

Hotel Riu Plaza Chicago

4.0 star property
9.4 out of 10, Exceptional, (2506)
"Nice hotel with amazing breakfasts and location."
The price is ￥25,401
￥34,031 total
includes taxes & fees
Oct 29 - Oct 30
Hotel Riu Plaza Chicago
La Quinta Inn & Suites by Wyndham Chicago Downtown
Exterior

La Quinta Inn & Suites by Wyndham Chicago Downtown

3.0 star property
8.6 out of 10, Excellent, (2572)
"Good place to stay"
The price is ￥26,759
￥34,046 total
includes taxes & fees
Oct 5 - Oct 6
La Quinta Inn & Suites by Wyndham Chicago Downtown
Hyatt Centric The Loop Chicago
Rooftop terrace

Hyatt Centric The Loop Chicago

4.0 star property
9.0 out of 10, Wonderful, (2160)
"Great place and really nice people "
The price is ￥30,895
￥36,268 total
includes taxes & fees
Oct 3 - Oct 4
Hyatt Centric The Loop Chicago
Sonesta ES Suites Chicago Downtown Magnificent Mile - Medical
Lobby

Sonesta ES Suites Chicago Downtown Magnificent Mile - Medical

3.0 star property
8.4 out of 10, Very Good, (2199)
"All the staff were amazing and very helpful with my whole stay would recommend and would love to cone back in the future. "
The price is ￥23,799
￥27,938 total
includes taxes & fees
Oct 29 - Oct 30
Sonesta ES Suites Chicago Downtown Magnificent Mile - Medical
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most.
Downtown Chicago showing a city

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile - River North

Magnificent Mile

Upscale shopping district with luxury department stores, boutiques, and acclaimed restaurants, featuring landmarks like the Wrigley Building and Chicago Water Tower. The Magnificent Mile is easily accessible by public transit and seasonal trolley service.

The Loop - Downtown which includes a river or creek

The Loop

Chicago's central business district boasts numerous global businesses, retail establishments, and theaters. Explore the Loop Retail Historic District, Chicago Landmark Historic Michigan Boulevard District, and visit iconic attractions like the Art Institute of Chicago.

River North showing railway items, street scenes and a city

River North

Artistic spirit thrives here, with art galleries and a design district featuring luxury interior furnishings. Explore Kingsbury Park, enjoy vibrant nightlife on Hubbard Street, and visit the iconic Contemporaine Building.

Chicago which includes modern architecture and a city

Lincoln Park

Upscale national retailers, boutiques, and bookstores abound in this affluent area, alongside numerous restaurants and coffee shops. Must-see attractions include Lincoln Park Zoo, Chicago History Museum, and North Avenue Beach. Easily accessible via CTA transit and major roads.

Top Illinois Medical District Hotel Reviews

citizenM Chicago Downtown

citizenM Chicago Downtown

10/10 Excellent
"Friendly, stylish, thoughtful and well located"
Laura 2-night trip
Posted 1 day ago
citizenM Chicago Downtown

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Illinois Medical District?

Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighborhood has to offer.

Where is the best place to stay in Illinois Medical District?

Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighborhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.

How many hotels are there in the Illinois Medical District area?

If you're searching for places to stay in Chicago, choose from one of Expedia's 16 hotels and other accommodations in Illinois Medical District.

If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?

Yes! Most hotel reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Illinois Medical District.

Where can I learn more about changing or cancelling my trip to Illinois Medical District?

To access more information about changing or cancelling your trip to Illinois Medical District, head over to our customer service page.

What can I see and do in this Chicago neighborhood?

Don't miss favorite places to visit in the surrounding area, such as Michigan Avenue, United Center, and Soldier Field. Michael Jordan Statue and National Museum of Mexican Art are also worth a visit when you're out sightseeing in Chicago.

How can I get around Illinois Medical District and the greater Chicago area?

Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.