Find Business Hotels in San Diego, CA

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on San Diego Business Hotels

Tonight
Dec 5 - Dec 6
Tomorrow
Dec 6 - Dec 7
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Top San Diego Business Hotels

Suite, 1 King Bed with Sofa Bed (Marina Tower Newly Renovated Marina view) | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

4.0 star property
Harbor Island
8.2 out of 10, Very Good, (3166)
"Great stay! "
United States
Melissa
The price is ￥14,578
￥22,340 total
includes taxes & fees
Dec 29 - Dec 30
Sheraton San Diego Resort
Outdoor pool, sun loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1843)
"Beautiful hotel, good bar, great staff and right on the bay and close to downtown and not to far away from local beaches. "
United States
Daniel
The price is ￥13,957
￥23,795 total
includes taxes & fees
Dec 20 - Dec 21
Hilton San Diego Bayfront
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillowtop beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (711)
"Great staff, great location, great value. "
United States
Juan
The price is ￥15,141
￥17,555 total
includes taxes & fees
Dec 14 - Dec 15
The DEXTRO Little Italy, BW Premier Collection
Lobby
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3.0 star property
Point Loma
7.4 out of 10, Good, (4092)
"Clean rooms and friendly staff."
United States
Aniket
The price is ￥13,112
￥15,071 total
includes taxes & fees
Dec 15 - Dec 16
Wyndham Garden San Diego Near SeaWorld
Courtyard
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4.0 star property
Carmel Valley
8.4 out of 10, Very Good, (1850)
"The room had a great view of the pool and staff was very friendly! "
United States
eva
The price is ￥17,400
￥19,826 total
includes taxes & fees
Dec 22 - Dec 23
DoubleTree by Hilton San Diego - Del Mar
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6064)
"Always an amazing stay"
United States
Jana
The price is ￥20,959
￥28,798 total
includes taxes & fees
Dec 10 - Dec 11
Wyndham San Diego Bayside
Reception
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3.0 star property
Point Loma
9.2 out of 10, Wonderful, (379)
"Great staff great breakfast and great room! "
United States
Evangelina
The price is ￥18,948
￥21,779 total
includes taxes & fees
Dec 15 - Dec 16
Hampton Inn & Suites by Hilton San Diego SeaWorld
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1934)
"Great hotel"
United States
Farzana
The price is ￥24,658
￥36,745 total
includes taxes & fees
Dec 12 - Dec 13
Marriott Marquis San Diego Marina
Exterior
 Hampton Inn & Suites San Diego Airport Liberty Station

 Hampton Inn & Suites San Diego Airport Liberty Station

2.5 star property
San Diego
9.2 out of 10, Wonderful, (1692)
"Clean, beautiful and a quiet place to stay"
United States
jennifer
The price is ￥20,967
￥24,100 total
includes taxes & fees
Jan 2 - Jan 3, 2026
 Hampton Inn & Suites San Diego Airport Liberty Station
Terrace/patio
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1267)
"Spacious and clean rooms, helpful staff"
United States
Gholam
The price is ￥15,265
￥17,547 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn San Diego/Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top San Diego Hotel Reviews

Kings Inn San Diego

Kings Inn San Diego

10/10 Excellent
"The check-in staff was amazing, my room is spacious and clean! The restaurant was absolutely delicious and as a traveler, I love and appreciate the wide selection on the television!"
Errin 1-night trip
Posted 1 day ago
Kings Inn San Diego

Explore a world of travel with Expedia

Frequently asked questions

How much do business-friendly hotels in San Diego cost?
You can expect to pay between ￥15,071 and ￥36,745 per night for business-friendly hotels in San Diego. Awesome deals on properties that are suitable for corporate travelers are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in San Diego?
A lot of corporate travelers recommend TownePlace Suites by Marriott San Diego Airport/Liberty Station. This 3-stars stay offers amenities such as a barbecue grill and a swimming pool. Tower23 Hotel is another top-rated option. It has a 4-stars rating and conveniences including an ocean view and a Tempur-Pedic mattress. You can pick from multiple business-friendly hotels in San Diego that have a total average guest review rating of 8.5.
How many business-friendly hotels are there in San Diego?
San Diego offers 248 hotels that accommodate corporate travelers. Whether you're searching for a central location or conveniences like dependable WiFi and conference rooms, you'll find the right property on Expedia.
What are the best cheap business-friendly hotels in San Diego?
TownePlace Suites by Marriott San Diego Airport/Liberty Station is a great choice for corporate travelers after a money-saving option. It comes with amenities like a swimming pool and a barbecue grill. Another economical stay for a work-related trip is  Hampton Inn & Suites San Diego Airport Liberty Station. An electric car charging station and a swimming pool are two of the conveniences here. Rates for business-friendly hotels in San Diego start at only ￥15,071 per night, so you'll have cash left over to spend on post-meeting activities. However, your San Diego visit shouldn't be all work and no play. Check out a few fun and free attractions, such as Mission Bay and Mission Beach. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in San Diego?
Crown City Inn is a top pick, located about 3 kilometers southwest of downtown San Diego. Offering pool sun loungers and a garden, this business-friendly motel has what you need to get the job done. The Rambler Motel also caters to corporate travelers. It's around 10 kilometers southeast of central San Diego and includes a firepit, a swimming pool and more.There are so many things to do and see around San Diego. Take time out from your hectic schedule to visit leading attractions like San Diego Zoo and Mission Bay.
Are there any family-friendly hotels in San Diego that are also business friendly?
Pacific Terrace Hotel is a top pick for both leisure and corporate guests. A nearby theme park and a nearby beach are just two of the amenities you'll find at this 4-stars San Diego escape. Alternatively, get away with the family and get down to business at Homewood Suites by Hilton San Diego Airport/Liberty Station. Enjoy the use of conveniences such as complimentary breakfast and a playground at this leading 3-stars property. San Diego has plenty of family-friendly attractions to discover once you've wrapped up work. Make new memories with the kids at San Diego Zoo and Mission Bay.
Are there any 5-star business-friendly hotels in San Diego?
Book your spot at Pendry San Diego. Around 0.64 kilometers from the downtown area of San Diego, this business-friendly retreat has a 5-star rating and amenities including designer toiletries and room service. THE US GRANT, a Luxury Collection Hotel, San Diego is another 5-star pick that's ideal for corporate guests. It's situated about 0.16 kilometers from the city center and offers designer toiletries and concierge services.
Why book your business-friendly hotel in San Diego with Expedia?
Expedia is here to help you find an ideal business-friendly hotel when you need to travel for work. From conference spaces and meeting rooms to on-site cafés and more, our stays have the things you need to get the job done.
How can I find cheap business-friendly hotels in San Diego?
When work takes you on the road in San Diego, our "business friendly" filter will help you find the right hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to get the job done. Another handy tip? Narrow your search by your preferred star rating and budget to see the cheapest accommodations.
What is there to do in San Diego near my business-friendly hotel?
Whatever you love to do, San Diego has loads to keep you occupied. San Diego Zoo, Mission Bay and Mission Beach are on most visitors' sightseeing plans. Don't go home without exploring Coronado Beach, Seaport Village and Old Town San Diego State Park either. With Expedia's business-friendly hotel deals, you can discover even more wonderful attractions like these with the cash you save.