The Best Hotels Closest to San Diego Natural History Museum in San Diego for 2026

The entrance to the Natural History Museum with a grand staircase leading up to the doors.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for San Diego Natural History Museum hotels

A hotel room with a herringbone-patterned floor, a bed, a chair, and curtains with room numbers.

A modern office space with a reception desk, seating area, and plants.

A modern lounge area with a blue sofa, yellow armchair, and a coffee table with a book and a potted plant.

1. Stay Classy Hostel

East Village, 2.3 km from San Diego Natural History Museum

Wai Kit

￥10,254

￥11,664 total

includes taxes & fees

Aug 23 - Aug 24

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

An outdoor seating area with sofas and chairs, a wooden staircase, and potted plants.

2. City24 Hotel Little Italy Mission Hills

2.3 km from San Diego Natural History Museum

omokayode

￥21,127

￥29,201 total

includes taxes & fees

Sep 1 - Sep 2

A modern bedroom with a brick wall, a bed, a desk, and a seating area.

A modern bathroom with a sink, mirror, and a bed with a red pillow.

A cafe with outdoor seating, a sign reading "INFUSED DRINKS NATURE'S KITCHEN," and a "BREAKFAST @ Cafe21" sign.

A modern living room with a brick wall, a flat-screen TV, a round red rug, and a seating area with a sofa and chairs.

3. Keating Hotel By At Mine Hospitality

East Village, 2.3 km from San Diego Natural History Museum

Jeffrey D

￥8,240

￥21,849 total

includes taxes & fees

Sep 2 - Sep 3

A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.

A lobby with a purple-lit ceiling, a large wall mural, and seating areas.

A spacious bar/lounge area with leather seating, a bar counter, and hanging pendant lights.

A modern lobby with seating areas, a reception desk, and a sign indicating elevators to parking and a street.

4. Marriott Vacation Club®, San Diego

1.8 km from San Diego Natural History Museum

Mabel

￥26,741

￥31,006 total

includes taxes & fees

Sep 7 - Sep 8

A bar area with a glass ceiling, a central bar counter, and multiple stools.

A dimly lit room with patterned walls, a wooden table, and a chair.

A luxurious interior with a large chandelier, patterned sofas, and a view of a cityscape through a large window.

A checkered floor with round tables and chairs, a patterned ceiling, and large windows.

5. Lafayette Hotel & Club

2.6 km from San Diego Natural History Museum

Jorgen

￥39,399

￥45,287 total

includes taxes & fees

Sep 7 - Sep 8

A rooftop pool with lounge chairs and a city skyline in the background.

A modern living room with a large sliding glass door leading to a balcony, a leather sofa, a coffee table with a board game, and a flat-screen TV.

A modern building with a sign reading "kasa little Italy" and a glass entrance.

A modern lobby with seating areas, large windows, and indoor plants.

6. Kasa Little Italy San Diego

2.3 km from San Diego Natural History Museum

Victor

￥32,398

￥50,799 total

includes taxes & fees

Aug 23 - Aug 24

A spacious dining area with high ceilings, large chandeliers, and a modern interior design.

A bar area with a high ceiling, patterned wall, and seating.

A rooftop pool area with lounge chairs and a view of the building's brick facade.

A multi-story hotel with a prominent 'PENDR' sign, large windows, and a corner entrance.

7. Pendry San Diego

Gaslamp Quarter, 2.8 km from San Diego Natural History Museum

Matthew

￥46,678

￥62,797 total

includes taxes & fees

Sep 13 - Sep 14

A restaurant with outdoor seating, brick walls, and decorative lighting.

A spacious lobby with a high ceiling, large windows, and a central chandelier.

A vintage car parked in front of a building with a sign that reads "Horton Grand Hotel."

A spacious lobby with high ceilings, large windows, and elegant furniture.

8. The Horton Grand, Downtown/Gaslamp Quarter

Marina District, 2.8 km from San Diego Natural History Museum

RONNIE

￥22,548

￥30,547 total

includes taxes & fees

Aug 23 - Aug 24

An aerial view of a resort with multiple swimming pools, lounge areas, and palm trees.

A marina with numerous boats docked, a large ship in the background, and a modern building with balconies.

An outdoor patio area with tables and chairs, a fire pit, and string lights.

A bar area with a long counter, multiple stools, and hanging wicker lamps.

9. Marriott Marquis San Diego Marina

Marina District, 3.1 km from San Diego Natural History Museum

CHLOE

￥34,178

￥47,126 total

includes taxes & fees

Sep 7 - Sep 8

A hotel entrance with a stone archway, multiple windows, and potted plants.

A variety of potted plants, including cacti and other greenery, arranged in front of a building with large windows.

A spacious living room with a high ceiling, multiple seating areas, and abundant indoor plants.

A cozy lounge area with wooden furniture, a fireplace, and lush tropical plants.

10. Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Gaslamp Quarter, 2.2 km from San Diego Natural History Museum

Pamela Ann Callum

￥26,741

￥31,006 total

includes taxes & fees

Sep 7 - Sep 8

A modern interior with a round table, two chairs, a hanging lamp, and a view of urban buildings through large windows.

A modern living room with a black leather sofa, two round tables, and a dining table with chairs. A large window offers a view of city buildings.

A modern kitchen with a built-in washer, a coffee maker, and a large window with a view of buildings.

A modern interior with a long wooden table, blue bar stools, a sofa, and large windows offering a view of the street.

11. The Margot Hotel San Diego Gaslamp Quarter, Outset by Hilton

East Village, 2.5 km from San Diego Natural History Museum

Diane

￥23,225

￥32,434 total

includes taxes & fees

Aug 31 - Sep 1

A multi-level interior with a staircase, wooden doors, and a balcony with plants.

A kitchen area with stainless steel appliances, a coffee machine, and a counter with various kitchen tools.

A hotel lobby with a blue patterned carpet, a green leather sofa, a red leather sofa, and a wooden railing with plants.

An outdoor dining area with tables and orange umbrellas, surrounded by buildings including the WM. PENN HOTEL.

12. Gaslamp Hostel

Gaslamp Quarter, 2.4 km from San Diego Natural History Museum

Karin

￥17,156

￥19,515 total

includes taxes & fees

Aug 27 - Aug 28

A luxurious room with a grand piano, plush blue sofas, ornate chandeliers, and elegant decor.

A luxurious lobby with a grand chandelier, plush blue sofas, and ornate decor.

A fountain with multiple water jets in a courtyard with seating and potted plants.

A rooftop terrace with white sofas, a fountain, and potted plants.

13. Westgate Hotel

2.3 km from San Diego Natural History Museum

Susan

￥27,521

￥37,413 total

includes taxes & fees

Aug 31 - Sep 1

A rooftop lounge with a view of the city and ocean, featuring a sofa, chairs, and round tables.

A harbor with boats, a large building, and a parking area.

A modern hotel with a prominent yellow and blue facade, large windows, and a well-lit entrance area with palm trees.

A dining area with round tables set for a formal event, large windows offering a view of the city, and elegant floral arrangements.

14. Springhill Suites San Diego Downtown/Bayfront

2.8 km from San Diego Natural History Museum

Colleen

￥29,747

￥34,559 total

includes taxes & fees

Sep 7 - Sep 8

A modern bar area with a curved counter, multiple bar stools, and a large window offering a view of the cityscape.

A spacious lobby with a high ceiling, a large sectional sofa, multiple seating areas, and a modern chandelier.

An outdoor patio area with seating arrangements, including sofas, chairs, and round tables.

A spacious lobby with large windows, curved ceiling, and comfortable seating areas.

15. Omni San Diego Hotel at the Ballpark

Gaslamp Quarter, 3 km from San Diego Natural History Museum

Andrew

￥20,127

￥30,492 total

includes taxes & fees

Sep 7 - Sep 8

An outdoor dining area with tables and chairs, a fire feature, and a view of the water and city skyline.

A modern hotel with multiple floors, a central courtyard, and surrounding high-rise buildings.

A spacious living room with a large window, a round coffee table, and modern seating.

A large building with a central dome and arched windows, surrounded by a reflective pond and colorful flowers.

16. InterContinental San Diego by IHG

2.9 km from San Diego Natural History Museum

Juan Ramon

￥40,823

￥57,977 total

includes taxes & fees

Sep 7 - Sep 8

A rooftop terrace with outdoor seating, a view of the city, and a large window overlooking the harbor.

A hotel room with a large window offering a view of a marina with boats and a cityscape.

A hotel room with a large window offering a city view, a beige sofa with a red pillow, a floor lamp, and a small white table.

A dining area with round tables, chairs, and floral centerpieces.

17. Residence Inn by Marriott San Diego Downtown/Bayfront

2.8 km from San Diego Natural History Museum

Traci

￥38,932

￥45,127 total

includes taxes & fees

Sep 13 - Sep 14

An outdoor dining area with tables and chairs, a menu stand, and a view of a street with palm trees and a building in the background.

A modern bar area with a circular bar, multiple stools, and a large screen.

A modern lobby with a digital display wall, reception desks, and a spacious, well-lit area.

18. Hard Rock Hotel San Diego

Gaslamp Quarter, 2.9 km from San Diego Natural History Museum

Anthony

￥28,019

￥40,124 total

includes taxes & fees

Aug 24 - Aug 25

A modern hotel room with a large bed, a sofa, a TV, and a city view.

A rooftop pool with lounge chairs and umbrellas, a clear sky, and a high-rise building in the background.

A high-rise hotel with multiple floors, a prominent curved glass facade, and a view of a bridge and water body in the background.

A spacious hotel dining area with multiple tables and chairs, large windows, and a view of the outdoors.

19. Manchester Grand Hyatt San Diego

Marina District, 3.1 km from San Diego Natural History Museum

Miguel

￥29,747

￥43,113 total

includes taxes & fees

Sep 7 - Sep 8

A cozy outdoor seating area with a fireplace, cushioned seating, and potted plants.

A spacious outdoor seating area with multiple tables and chairs, surrounded by large windows and potted plants.

A hotel room with a large bed, a chair, a TV, and two large windows with curtains.

A modern bathroom with a large mirror, two sinks, and a seating area with two chairs and a small table.

20. The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

2.6 km from San Diego Natural History Museum

Jonathan

￥31,488

￥36,508 total

includes taxes & fees

Aug 25 - Aug 26

View all properties

Compare popular hotels close to San Diego Natural History Museum

Property	Star rating	Guest rating
Stay Classy Hostel	9.6 Exceptional 928 reviews	View
City24 Hotel Little Italy Mission Hills	9.6 Exceptional 191 reviews	View
Keating Hotel By At Mine Hospitality	9.4 Exceptional 139 reviews	View
Marriott Vacation Club®, San Diego	9.4 Exceptional 1,166 reviews	View
Lafayette Hotel & Club	9.4 Exceptional 1,921 reviews	View

Top San Diego Natural History Museum Hotel Reviews

Hard Rock Hotel San Diego

10/10 Excellent

"Just a great stay!"

Manchester Grand Hyatt San Diego

10/10 Excellent

"Great location and facility."

Courtyard by Marriott San Diego Downtown Little Italy

8/10 Good

"Could use bigger pool. Nice hotel good location."

Ash&9th

10/10 Excellent

"Quiet and clean"

Lafayette Hotel & Club

10/10 Excellent

"The entire experience was excellent. Starting with the very personable valet, to the inviting check-in folks, to the attentive pool staff, they all get it. Everyone is friendly, care about your experience, and set the vibe. Pool is a great scene and all the various amentities from the jazz club, the bowling alley, the diner, are fun, clean, and well run. Coming back for sure!"

Palihotel San Diego Gaslamp Quarter

8/10 Good

"great location for downtown especially if you’re going to petco park."

The US Grant, a Luxury Collection Hotel, San Diego

10/10 Excellent

"Lovely hotel, excellent location with a lot of restaurants close by. A few blocks to the pier. Hotel staff was very helpful. We enjoyed our stay."

Little Italy Inn - Limited Service Apart Hotel

10/10 Excellent

"Property is clean, reasonable price, friendly reception people and the location is great. I just needed a place to sleep and tour the area during the two days I stayed!"

Holiday Inn Express San Diego Downtown by IHG

8/10 Good

"Helpful staff and I love the breakfast they offer in the morning. The only thing I don't like is the hallway going to my room. It looks like it was a decade since they have done a carpet cleaning. I stayed in 3rd floor. When you go outside the building where you wait for your ride it is smell bad. It smell strong pee and I think that is coming from the dogs that the residents owe from the The Cortez condos. I hope HIE will take actions on these comments as this is a turn off to visitors."

Other attractions near San Diego Natural History Museum

Fleet Science Center

Discover science through exhibits that will delight the entire family. Watch an IMAX film at San Diego’s museum and planetarium.

See properties

A colorful courtyard with a tiled floor, a bench, and a fountain.

Spanish Village Art Center

Enjoy an outing to Spanish Village Art Center during your stay in San Diego. Discover the area's top-notch restaurants and its acclaimed theater scene.

See properties

A detailed model of a town with a church, train tracks, and a bridge.

San Diego Model Railroad Museum

You can spend time studying the exhibits at San Diego Model Railroad Museum in San Diego. Stroll along the area's seaside or experience its acclaimed art scene.

See properties

A symmetrical garden with a central reflecting pool, palm trees, and classical architecture.

Casa de Balboa

You can learn about the history of San Diego when you stop by Casa de Balboa. Stroll along the area's beautiful beaches or experience its fascinating museums.

See properties

A gallery with classical paintings on display.

Museum of Photographic Arts

Visit this museum to journey through the history of the photography medium, which both captures the real world and transforms it into art.

See properties

A desert landscape with large cacti and sparse trees.

Desert Garden

No other garden is as natural to San Diego as this slightly secluded area. Stroll through this green space to see plant species not commonly found in other parks.

See properties

A garden with a pond, colorful flowers, palm trees, and a large building with a dome.

Botanical Building

Discover thousands of plants inside the historic centerpiece of San Diego’s Balboa Park, which was originally built for the 1915 Panama–California Exposition.

See properties

An art gallery with pink walls and ceiling, featuring classical paintings and a central table.

Timken Museum of Art

View a priceless collection of masterpieces from Europe, the U.S. and Russia in this gorgeous community museum, known as San Diego’s jewel box of art.

See properties

Frequently asked questions

What's the area like around San Diego Natural History Museum?

San Diego Natural History Museum is located in an area of San Diego known for its beautiful ocean views, array of dining options, and popular zoo. If you're looking for a convenient place to stay, check out the 103 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to San Diego Natural History Museum?

Manchester Grand Hyatt San Diego is one of the top choices for your stay based on our traveler data, and this hotel offers 6 restaurants and 3 bars. It's located 1.9 mi (3.1 km) from San Diego Natural History Museum. Other good choices within a few miles include Wyndham San Diego Bayside and The DEXTRO Little Italy, BW Premier Collection.

How many hotels can I expect to find near San Diego Natural History Museum?

Expedia has 103 hotels and other accommodations within a mile from San Diego Natural History Museum.

If I need to cancel the hotel reservation for my stay near San Diego Natural History Museum, will I receive a refund?

Yes! The majority of room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best deals near San Diego Natural History Museum.

Where can I learn more about changing or cancelling my trip in the area near San Diego Natural History Museum?

To find more details about picking new dates or cancelling your stay near San Diego Natural History Museum, go to https://www.expedia.com/service/.

What can I see and do near San Diego Natural History Museum?

San Diego Museum of Art, San Diego Air and Space Museum, and Maritime Museum of San Diego feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Hotel del Coronado, Whaley House Museum, and Mission Basilica San Diego de Alcala. You can check out the local talent at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Humphreys Concerts by the Bay.

Explore a world of travel with Expedia

Flights from San Diego

San Diego County Vacations

San Diego Vacation Rentals

Find hotels near San Diego Natural History Museum, San Diego from ￥11,664

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for San Diego Natural History Museum hotels

1. Stay Classy Hostel

2. City24 Hotel Little Italy Mission Hills

3. Keating Hotel By At Mine Hospitality

4. Marriott Vacation Club®, San Diego

5. Lafayette Hotel & Club

6. Kasa Little Italy San Diego

7. Pendry San Diego

8. The Horton Grand, Downtown/Gaslamp Quarter

9. Marriott Marquis San Diego Marina

10. Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

11. The Margot Hotel San Diego Gaslamp Quarter, Outset by Hilton

12. Gaslamp Hostel

13. Westgate Hotel

14. Springhill Suites San Diego Downtown/Bayfront

15. Omni San Diego Hotel at the Ballpark

16. InterContinental San Diego by IHG

17. Residence Inn by Marriott San Diego Downtown/Bayfront

18. Hard Rock Hotel San Diego

19. Manchester Grand Hyatt San Diego

20. The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

Compare popular hotels close to San Diego Natural History Museum

Top San Diego Natural History Museum Hotel Reviews

Hard Rock Hotel San Diego

Manchester Grand Hyatt San Diego

Courtyard by Marriott San Diego Downtown Little Italy

Ash&9th

Lafayette Hotel & Club

Palihotel San Diego Gaslamp Quarter

The US Grant, a Luxury Collection Hotel, San Diego

Little Italy Inn - Limited Service Apart Hotel

Holiday Inn Express San Diego Downtown by IHG

Other attractions near San Diego Natural History Museum

Fleet Science Center

Spanish Village Art Center

San Diego Model Railroad Museum

Casa de Balboa

Museum of Photographic Arts

Desert Garden

Botanical Building

Timken Museum of Art

Frequently asked questions

Explore a world of travel with Expedia