Photo by Jessica King

Find hotels in De Soto, MO from ¥8,816

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Our top choices for De Soto hotels

Baymont by Wyndham Festus

Baymont by Wyndham Festus
3.0 star property
Festus
6.8 out of 10, (921)
"Room was clean and comfortable for an overnight stay"
United States
Jack
The price is ¥12,595
¥14,402 total
includes taxes & fees
Dec 14 - Dec 15
Baymont by Wyndham Festus

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very Good, (611)
Enjoy a refreshing swim in the seasonal outdoor pool and start your day with complimentary on-the-go breakfast. This motel offers free WiFi and parking, with friendly staff ready to assist. Located near Farmington Mineral Area Shopping Center and Dean Danieley Park.

"Clean, friendly staff, quiet"
United States
Stacy
The price is ¥8,196
¥9,330 total
includes taxes & fees
Dec 20 - Dec 21
Super 8 by Wyndham Farmington

Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
2.0 star property
Potosi
7.0 out of 10, Good, (379)
This business-friendly motel in Potosi offers convenient amenities including free WiFi, parking, and on-the-go breakfast served daily. Travelers consistently praise the helpful staff and spotlessly clean, comfortable accommodations.

"The room was very good for the price."
United States
Benjamin
The price is ¥8,591
¥9,386 total
includes taxes & fees
Dec 15 - Dec 16
Super 8 by Wyndham Potosi

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 star property
Festus
9.4 out of 10, Exceptional, (699)
Enjoy a comfortable stay at this business-friendly hotel with an indoor pool and fitness center. Start each day with free breakfast before exploring nearby Jorkerst Memorial Park and Sunset Park. The helpful staff and free parking enhance your Festus experience.

"Clean, spotless, great room, front desk staff was excellent! Parking great!"
United States
Rick
The price is ¥18,348
¥20,980 total
includes taxes & fees
Dec 14 - Dec 15
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
Arnold
9.4 out of 10, Exceptional, (1000)
This quiet Arnold hotel provides a convenient base near shopping and restaurants. Enjoy free WiFi, parking, and a refreshing outdoor pool after visiting nearby attractions. Helpful staff and fitness center ensure a comfortable stay.

"The staff was very friendly and the rooms were very nice and clean"
United States
Connie
The price is ¥13,993
¥16,175 total
includes taxes & fees
Dec 17 - Dec 18
Pear Tree Inn St. Louis Arnold

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very Good, (1003)
This Farmington hotel offers easy highway access near local restaurants in a quiet setting. Travelers appreciate the comfortable beds, helpful staff, and clean rooms. Enjoy the seasonal pool, 24-hour fitness center, and complimentary breakfast before exploring nearby parks.

"Room was clean , staff was friendly !"
United States
Sally
The price is ¥8,334
¥9,489 total
includes taxes & fees
Dec 21 - Dec 22
Baymont Inn and Suites by Wyndham Farmington, MO

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very Good, (884)
Enjoy a peaceful retreat at this Festus hotel offering complimentary breakfast, WiFi, and parking. The fitness center provides workout options while the helpful staff ensures a pleasant stay. Located conveniently near Jorkerst Memorial Park and Sunset Park.

"Staff was very nice ans helpful. Our room was clean and pleasant. "
United States
ELLEN
The price is ¥14,959
¥17,105 total
includes taxes & fees
Dec 14 - Dec 15
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
2.0 star property
Bonne Terre
7.0 out of 10, Good, (536)
Experience Missouri's natural beauty from this convenient motel with an indoor pool. Located near Bonne Terre Mine and St. Francois State Park, it's perfect for hiking and scuba diving adventures. Enjoy free breakfast, WiFi, and parking during your stay.

"There great work nd staff"
United States
Jorge
The price is ¥8,062
¥8,816 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Super 8 by Wyndham Bonne Terre

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (574)
Immerse yourself in this lodge with an 18-hole golf course and refreshing indoor pool. Located near Crown Pointe Golf Club and Dean Danieley Park, this Farmington hotel offers free breakfast, WiFi, and parking. Helpful staff ensure a memorable stay.

"Clean, friendly staff enjoyed the stay"
United States
John
The price is ¥18,054
¥20,554 total
includes taxes & fees
Dec 21 - Dec 22
Crown Pointe Lodge, BW Signature Collection

Quality Inn Farmington

Quality Inn Farmington
2.5 star property
Farmington
7.6 out of 10, Good, (861)
In Farmington, this welcoming hotel offers an indoor pool and free breakfast, parking, and WiFi. Hiking trails beckon nearby, while clean rooms provide a comfortable base for exploring Bicentennial Park. Guests consistently praise the helpful staff.

"The staff was friendly. We had a few issues with our stay but overall was good. Love there breakfast variety "
United States
edith
The price is ¥7,930
¥9,471 total
includes taxes & fees
Dec 28 - Dec 29
Quality Inn Farmington

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
2.5 star property
Festus
7.8 out of 10, Good, (911)
Peaceful hotel close to Sunset Park offers free breakfast, WiFi, and parking. Guests love the minimal noise levels and helpful staff. The fitness center provides workout options while being just a 10-minute drive from Mississippi River attractions.

"Vary clean"
United States
George
The price is ¥11,763
¥13,745 total
includes taxes & fees
Dec 14 - Dec 15
Comfort Inn Festus - St Louis South

Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (518)
Located near Mineral Area Shopping Center, this inviting hotel offers a morning swim in the indoor pool and a 24-hour fitness center. Free breakfast, WiFi and parking add value, while the helpful staff ensures a pleasant stay.

"Clean room, friendly staff."
United States
William
The price is ¥16,420
¥18,694 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn Farmington

WoodSpring Suites St. Louis Arnold

WoodSpring Suites St. Louis Arnold
2.5 star property
Arnold
6.0 out of 10, (439)
Enjoy convenient access to the Arnold Historical Society & Museum and BounceU from this welcoming hotel. With free WiFi, complimentary parking, and practical laundry facilities, guests appreciate the helpful staff that enhances every stay.

"Location was great as was staff"
United States
Randall
The price is ¥12,593
¥14,557 total
includes taxes & fees
Dec 18 - Dec 19
WoodSpring Suites St. Louis Arnold

Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (412)
Located minutes from Farmington Mineral Area Shopping Center, this hotel offers an indoor pool for year-round swimming and complimentary amenities including breakfast, WiFi, and parking. The fitness center provides workout options while the helpful staff ensures a pleasant stay.

"The staff was great!"
United States
Christopher
The price is ¥13,269
¥39,829 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express & Suites Farmington by IHG

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1001)
This comfortable hotel features a fitness center and two pools for year-round swimming. Located near Arnold Historical Society & Museum, guests love the helpful staff. Enjoy complimentary breakfast, WiFi, and parking for a convenient business-friendly stay.

"Clean room, comfortable bed, free breakfast, dinner and drinks every night! We had a great stay, will definitely stay again!"
United States
Jacqueline
The price is ¥19,124
¥22,106 total
includes taxes & fees
Dec 17 - Dec 18
Drury Inn & Suites St. Louis Arnold

The Conner House B&B

The Conner House B&B
3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (19)
Charming accommodation just a short drive from Fort de Chartes and the Mississippi River. Enjoy a daily full breakfast served between 7:00 AM and 9:30 AM, plus convenient amenities like free WiFi and complimentary self parking.

"Wonderful folks that work there. Nice b&b in a quiet , scenic area."
United States
Bradley
The price is ¥22,351
¥24,805 total
includes taxes & fees
Dec 22 - Dec 23
The Conner House B&B

Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast
2.5 star property
Maeystown
9.0 out of 10, Wonderful, (154)
Begin your day with free breakfast at this cozy Maeystown retreat. The B&B offers a welcoming coffee shop/cafe and relaxing bar/lounge. Enjoy convenient free WiFi and parking while exploring nearby Illinois Caverns State Natural Area.

"Hosts were excellent, very quiet and the breakfast was wonderful"
United States
Mark
The price is ¥19,029
¥21,118 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Corner George Inn Bed & Breakfast

Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (3)
Set in charming French Village, these cozy tiny houses offer full kitchenettes for home-cooked meals. Guests appreciate the free parking and picnic areas that create a perfect base for exploring the local countryside.

"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
Tiny Houses of French Village

YMCA Trout Lodge

YMCA Trout Lodge
2.0 star property
Potosi
10.0 out of 10, Exceptional, (1)
"When checking in the staff was great. Stay was relaxing. Only downside was the carpeted floors in the bunk bed room. Appears the carpet under the beds has not been vacuumed in a bit with the dust, dead bugs and cobwebs. Had my wife not dropped an ear ring, would never have noticed so not a big thing. "
United States
Leonard
The price is ¥25,127
¥26,941 total
includes taxes & fees
Jan 5 - Jan 6, 2026
YMCA Trout Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Kayaking down the Big River on a fall day!
Photo by Jessica King
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Frequently asked questions

Where is the best place to stay in De Soto?
Pear Tree Inn St. Louis Arnold, located 23.1 mi (37.2 km) from the heart of De Soto, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Baymont Inn and Suites by Wyndham Farmington, MO and Drury Inn & Suites St. Louis Arnold. See all available top hotels, or vacation rentals in De Soto.
What are some of the best vacation rentals that De Soto has to offer?
Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.: You might like this vacation home rental near De Soto. It is located in a rural location and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in De Soto.
If I need to cancel my hotel reservation in De Soto, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.
Where can I learn more about changing or cancelling my trip to De Soto?
For additional details about picking new dates or cancelling your trip to De Soto, go to https://www.expedia.com/service/.
What's the best pet-friendly hotel in De Soto?
What are some accommodations with pools in De Soto?
Pear Tree Inn St. Louis Arnold: Features buffet, an outdoor pool, and free self parking. Baymont Inn and Suites by Wyndham Farmington, MO and Drury Inn & Suites St. Louis Arnold are a couple of other choices with an onsite pool. View all hotels with pools in De Soto.
What is the best accommodation for staying close to Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What is staying in De Soto like?
Visitors can enjoy all that De Soto has to offer including its restaurants. In De Soto, there are 6 hotels and other accommodations to choose from. Find out more about De Soto.
What should I do while I'm visiting De Soto?
Natural beauty is on display at Sunrise Lake Beach, Big River, and Big Lake. A couple of additional sights to add to your agenda are Washington State Park and Redfield's Flea Market. Check out what more to see and do in Expedia's De Soto guide.
What's the seasonal weather like in De Soto?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.

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