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Compare 4,139 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Check out Port of San Juan and El Yunque National Forest—just two of the popular sights around Santa Cruz.

Top Santa Cruz Hotel Reviews

Frequently asked questions

Where is the best place to stay in Santa Cruz?

Fairmont El San Juan Hotel, located 8.1 mi (13 km) from the heart of Santa Cruz, is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Hyatt Regency Grand Reserve Puerto Rico and Wyndham Grand Rio Mar Rainforest Beach and Golf Resort. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best vacation rentals that Santa Cruz has to offer?

1120 Vieques by Stay with Bear: Visitors like this Santa Cruz vacation home rental. It is near the airport and equipped with air-conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To access more information about rescheduling or cancelling your trip to Santa Cruz, head over to our customer service page.

What are some hotels with pools in Santa Cruz?

Best Western Plus Condado Palm Inn & Suites: 3-star hotel, 4-minute walk from Casino del Mar at La Concha Resort. Features free bike rentals, a pool, and sun loungers. Wyndham Grand Rio Mar Puerto Rico Golf & Beach Resort and Fairmont El San Juan Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Santa Cruz.

How is it to stay in Santa Cruz?

Those traveling to Santa Cruz are sure to enjoy the sights to see and things to do. Around the area, top sights include Port of San Juan, El Yunque National Forest, and Condado Beach. In Santa Cruz, there are 2 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What should I see while I'm in Santa Cruz?

Notable places to visit in the wider area include Port of San Juan, El Yunque National Forest, and Condado Beach. Additionally, you'll find Pan American Pier and Luquillo Beach in the area. Check out what more to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually September and August with an average temp of 81°F, while the coldest months are March and January with an average of 77°F. Average annual precipitation for Santa Cruz is 39 inches.