Find hotels in Grand Center, St. Louis from ¥12,738
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Discover 1,762 Grand Center hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Grand Center hotels

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center Inn
Grand Center Inn

White House at Grand Central
White House at Grand Central

Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch

Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport

Drury Inn & Suites St. Louis Union Station
Drury Inn & Suites St. Louis Union Station
Where to stay in Grand Center

Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Top Grand Center Hotel Reviews
Explore a world of travel with Expedia
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Hotels in top St. Louis neighborhoods
- Hotels in Downtown St. Louis
- Hotels in Clayton
- Hotels in Central West End
- Hotels in Creve Coeur
- Hotels in Downtown West
- Hotels in St. Charles Historic District
- Hotels in Soulard
- Hotels in The Hill
- Hotels in University City
- Hotels in Midtown
- Hotels in Ladue
- Hotels in Tower Grove South
- Hotels in The Grove
- Hotels in Dogtown
- Hotels in Shaw
- Hotels in Lafayette Square
- Hotels in Tower Grove East
- Hotels in Lindenwood Park
- Hotels in LaSalle Park
- Hotels in Cahokia
More Accommodation Types in Grand Center
Explore more hotels
- Pear Tree Inn St. Louis Airport
- Marriott St. Louis Grand
- Forest Park Hotel by MDR
- River City Casino & Hotel
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Drury Inn & Suites St. Louis Union Station
- AC Hotel St. Louis Clayton
- Live by Loews - St.Louis
- Best Western Plus The Charles Hotel
- Moonrise Hotel
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