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Discover 1,770 Grand Center hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

White House at Grand Central

Grand Center Inn

Drury Plaza Hotel St. Louis at the Arch

Pear Tree Inn St. Louis Airport

Drury Inn & Suites St. Louis Union Station
Where to stay in Grand Center

Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
Top Grand Center Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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Frequently asked questions
Hotels in top St. Louis neighborhoods
- Hotels in Downtown St. Louis
- Hotels in Clayton
- Hotels in Central West End
- Hotels in St. Charles Historic District
- Hotels in Creve Coeur
- Hotels in Downtown West
- Hotels in Soulard
- Hotels in The Hill
- Hotels in Midtown
- Hotels in University City
- Hotels in Ladue
- Hotels in The Grove
- Hotels in Dogtown
- Hotels in Shaw
- Hotels in Tower Grove South
- Hotels in Lafayette Square
- Hotels in Tower Grove East
- Hotels in Lindenwood Park
- Hotels in Downtown Clayton
More Accommodation Types in Grand Center
Explore more hotels
- St. Louis Union Station Hotel, Curio Collection by Hilton
- 21C Museum Hotel St Louis
- The Arch Convention Hotel
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- The Cheshire
- Marriott St. Louis Grand
- Hollywood Casino & Hotel St. Louis
- Live by Loews - St.Louis
- River City Casino & Hotel
- Moonrise Hotel
- Pear Tree Inn St. Louis Near Union Station
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