What is Southhampton like?

Travelers to the Southhampton neighborhood in St. Louis will be sure to enjoy their stay.

How many hotels will I find in the Southhampton area?

When you want to kick up your feet after a day of exploring the sights in St. Louis, you can choose from 18 Expedia hotels and other accommodations in Southhampton.

If I need to cancel my hotel reservation in Southhampton, will I receive a refund?

Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best deals in Southhampton.

Where can I learn more about changing or cancelling my trip to Southhampton?

To find more details about rescheduling or cancelling your trip to Southhampton, click here .

What can I see and do in this St. Louis neighborhood?

A few places to visit in the area around Southhampton include The Heavy Anchor, Das Bevo, and Miniature Museum of Greater St. Louis. When you're sightseeing in St. Louis, Lindenwood Park and River des Peres Greenway Trailhead are also worth a stop.

Top Southhampton Hotels

A city skyline at dusk with a prominent bridge arching over a body of water.

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Our top choices for Southhampton hotels

A lobby with a reception desk, seating area, and a bicycle in the background.

1. Drury Inn & Suites St. Louis Forest Park

3.3 km from Southhampton

Robert

￥24,924 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

2. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 4.7 km from Southhampton

Jennifer

￥27,332 total

includes taxes & fees

Oct 26 - Oct 27

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

3. SpringHill Suites St. Louis Brentwood

5.9 km from Southhampton

Aaron

￥21,534 total

includes taxes & fees

Oct 18 - Oct 19

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

4. River City Casino & Hotel

6.7 km from Southhampton

jodi

￥20,294 total

includes taxes & fees

Oct 11 - Oct 12

The Clayton Plaza Hotel sign with a stone wall and plants in front.

5. Clayton Plaza Hotel & Extended Stay

8.2 km from Southhampton

Daniele

￥16,891 total

includes taxes & fees

Oct 25 - Oct 26

A courtyard with outdoor seating, a central fountain, and a view of a tower.

6. The Knight Center at Washington University

7.4 km from Southhampton

Rosalyn

￥27,334 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

7. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 5.3 km from Southhampton

paullita jeanne

￥28,709 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

8. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 7.9 km from Southhampton

Vicky

￥21,857 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a chair, a desk, and a large window.

9. Forest Park Hotel by MDR

The Hill, 3.4 km from Southhampton

Kevan

￥15,180 total

includes taxes & fees

Nov 3 - Nov 4

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

10. The Cheshire

5.5 km from Southhampton

Matthew

￥27,827 total

includes taxes & fees

Oct 25 - Oct 26

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

11. Drury Plaza Hotel St. Louis Brentwood

6.9 km from Southhampton

Janell

￥24,935 total

includes taxes & fees

Nov 1 - Nov 2

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

12. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 6.5 km from Southhampton

Tosha

￥34,637 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a wooden floor, a desk with drawers, a chair, a bed with a headboard, and curtains.

13. 21C Museum Hotel St Louis

Downtown West, 8.7 km from Southhampton

Zane

￥27,314 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

14. DoubleTree by Hilton St. Louis Forest Park

Central West End, 6 km from Southhampton

may

￥27,695 total

includes taxes & fees

Oct 25 - Oct 26

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

15. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 9.5 km from Southhampton

David

￥24,972 total

includes taxes & fees

Oct 30 - Oct 31

A rooftop restaurant with round tables, chairs, and a view of the city.

16. Moonrise Hotel

7.7 km from Southhampton

Katherine

￥24,789 total

includes taxes & fees

Oct 27 - Oct 28

A modern hotel with a prominent 'aloft' sign, a 'WXYZ' sign, and a 'Coming Soon' advertisement on the side.

17. Aloft by Marriott St Louis Central West End

Central West End, 6.1 km from Southhampton

Brittany

￥21,031 total

includes taxes & fees

Oct 11 - Oct 12

A bar area with a long counter displaying numerous bottles of alcohol and several empty wine glasses lined up.

18. Holiday Inn St Louis SW - Route 66 by IHG

11.3 km from Southhampton

Eric

￥22,161 total

includes taxes & fees

Oct 11 - Oct 12

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

19. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 9.5 km from Southhampton

Karen

￥21,715 total

includes taxes & fees

Nov 1 - Nov 2

A rooftop terrace with wicker furniture, offering a city view.

20. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 9.3 km from Southhampton

Kevin Roy

￥24,924 total

includes taxes & fees

Oct 11 - Oct 12

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Where to stay in Southhampton

Find the best Southhampton areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

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A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top Southhampton Hotel Reviews

Moonrise Hotel

10/10 Excellent

"I love the Moonrise and will stay here anytime I come to St. Louis. I have stayed here multiple times and never had a negative experience. Easy parking, walking to food, next door to concert venues, plus pet friendly. The rooftop bar is great too!"

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Staff is great, clean room, good breakfast. Had a slight problem getting shuttle back to hotel, due to a large group coming in. Already had been told where to pick shuttle up from driver after being dropped off . Called for shuttle for pick up and was told to meet at different location which I could not find. Asked for assistance at Airport and they kindly called inn to help me for location pick up. Otherwise great stay."

21C Museum Hotel St Louis

8/10 Good

"Great location. Parking is expensive unless you can find street parking. It is a really neat old building make sure you walk around! We had a weird light that would not turn off I our room. Maintenance came and had to put tape and cardboard over it. Effective but not a long term solution for dum design"

Find hotels in Southhampton, St. Louis

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Our top choices for Southhampton hotels

1. Drury Inn & Suites St. Louis Forest Park

2. Hampton Inn & Suites St. Louis at Forest Park

3. SpringHill Suites St. Louis Brentwood

4. River City Casino & Hotel

5. Clayton Plaza Hotel & Extended Stay

6. The Knight Center at Washington University

7. Home2 Suites by Hilton St. Louis/Forest Park

8. Fairfield Inn & Suites by Marriott St. Louis Downtown

9. Forest Park Hotel by MDR

10. The Cheshire

11. Drury Plaza Hotel St. Louis Brentwood

12. The Royal Sonesta Chase Park Plaza St. Louis

13. 21C Museum Hotel St Louis

14. DoubleTree by Hilton St. Louis Forest Park

15. Hyatt Regency St. Louis at The Arch

16. Moonrise Hotel

17. Aloft by Marriott St Louis Central West End

18. Holiday Inn St Louis SW - Route 66 by IHG

19. Embassy Suites by Hilton St. Louis Downtown

20. Drury Plaza Hotel St. Louis at the Arch

Where to stay in Southhampton

Downtown St. Louis

Clayton

Central West End

St. Charles Historic District

Creve Coeur

Top Southhampton Hotel Reviews

Moonrise Hotel

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