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Discover 1,732 Southhampton hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Southhampton hotels

Pear Tree Inn St. Louis Arnold
Lobby

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1004)
"Clean, comfortable and pleasant stay."
The price is ￥13,266
￥15,334 total
includes taxes & fees
Sep 22 - Sep 23
Pear Tree Inn St. Louis Arnold
Drury Inn & Suites St. Louis Collinsville
Lobby

Drury Inn & Suites St. Louis Collinsville

3.0 star property
9.6 out of 10, Exceptional, (1000)
"Great place to stay "
The price is ￥16,362
￥18,814 total
includes taxes & fees
Sep 22 - Sep 23
Drury Inn & Suites St. Louis Collinsville
Drury Plaza Hotel St. Louis St. Charles
Lobby

Drury Plaza Hotel St. Louis St. Charles

3.0 star property
9.6 out of 10, Exceptional, (1008)
"Its a great place to stay to enjoy the City."
The price is ￥16,215
￥18,798 total
includes taxes & fees
Oct 5 - Oct 6
Drury Plaza Hotel St. Louis St. Charles
The Principal Hotel
Exterior

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (131)
"Very clean place to stay. We would definitely come back. "
The price is ￥15,301
￥16,981 total
includes taxes & fees
Sep 10 - Sep 11
The Principal Hotel
Pear Tree Inn St. Louis Airport
Lobby

Pear Tree Inn St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (2704)
"Great place to stay!"
The price is ￥13,266
￥15,617 total
includes taxes & fees
Sep 22 - Sep 23
Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch
Rooftop terrace

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (3045)
"Great location, great food at reception, wonderful breakfast."
The price is ￥17,689
￥20,682 total
includes taxes & fees
Oct 9 - Oct 10
Drury Plaza Hotel St. Louis at the Arch
The Knight Center at Washington University
Pub

The Knight Center at Washington University

2.5 star property
9.4 out of 10, Exceptional, (398)
"Nice place. We had a nice stay"
The price is ￥23,685
￥27,236 total
includes taxes & fees
Sep 28 - Sep 29
The Knight Center at Washington University
Drury Inn & Suites St. Louis Fairview Heights
1 bedroom, desk, blackout drapes, iron/ironing board

Drury Inn & Suites St. Louis Fairview Heights

3.0 star property
9.2 out of 10, Wonderful, (1005)
"Great stay! "
The price is ￥13,782
￥15,570 total
includes taxes & fees
Sep 29 - Sep 30
Drury Inn & Suites St. Louis Fairview Heights
River City Casino & Hotel
Daily cooked-to-order breakfast for a fee

River City Casino & Hotel

4.0 star property
9.0 out of 10, Wonderful, (1363)
"Beautiful hotel and room. "
The price is ￥22,113
￥27,909 total
includes taxes & fees
Sep 17 - Sep 18
River City Casino & Hotel
The Wildwood Hotel
Ballroom

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1572)
"Great place to stay."
The Wildwood Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lobby sitting area

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
8.2 out of 10, Very Good, (1003)
"Very good hotel for the price"
The price is ￥13,157
￥15,196 total
includes taxes & fees
Sep 22 - Sep 23
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Moonrise Hotel
Exterior

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1874)
"Love the place "
The price is ￥20,589
￥24,489 total
includes taxes & fees
Sep 14 - Sep 15
Moonrise Hotel
Drury Inn & Suites St. Louis Brentwood
Lobby

Drury Inn & Suites St. Louis Brentwood

3.0 star property
9.6 out of 10, Exceptional, (1001)
"Great stay with our family close to the zoo!"
The price is ￥19,458
￥23,107 total
includes taxes & fees
Sep 22 - Sep 23
Drury Inn & Suites St. Louis Brentwood
Best Western St. Louis-Kirkwood Route 66
Lobby

Best Western St. Louis-Kirkwood Route 66

3.5 star property
8.4 out of 10, Very Good, (1284)
"Good place to stay "
The price is ￥14,527
￥16,995 total
includes taxes & fees
Oct 5 - Oct 6
Best Western St. Louis-Kirkwood Route 66
Hyatt Regency St. Louis at The Arch
Lobby

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very Good, (4014)
"Close to all events great stay"
The price is ￥18,429
￥21,732 total
includes taxes & fees
Oct 2 - Oct 3
Hyatt Regency St. Louis at The Arch
Country Inn & Suites by Radisson, St. Charles Historic District
Free daily buffet breakfast

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1014)
"Great property for where we need to be."
The price is ￥16,792
￥19,299 total
includes taxes & fees
Sep 11 - Sep 12
Country Inn & Suites by Radisson, St. Charles Historic District
Best Western Plus St. Louis Airport Hotel
Exterior

Best Western Plus St. Louis Airport Hotel

2.5 star property
9.2 out of 10, Wonderful, (1005)
"Very convenient location!"
The price is ￥15,914
￥19,695 total
includes taxes & fees
Sep 29 - Sep 30
Best Western Plus St. Louis Airport Hotel
Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2931)
"Clean rooms excellent staff wonderful on site Breakfast"
The price is ￥15,406
￥17,946 total
includes taxes & fees
Sep 28 - Sep 29
Clayton Plaza Hotel & Extended Stay
Courtyard by Marriott St. Louis Brentwood
Terrace/patio

Courtyard by Marriott St. Louis Brentwood

3.0 star property
9.4 out of 10, Exceptional, (792)
"Great place to stay."
The price is ￥16,791
￥20,506 total
includes taxes & fees
Oct 5 - Oct 6
Courtyard by Marriott St. Louis Brentwood
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Bar (on property)

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4.0 star property
8.8 out of 10, Excellent, (1008)
"Staff was friendly and the hotel is beautiful"
The price is ￥15,628
￥18,587 total
includes taxes & fees
Sep 28 - Sep 29
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southhampton

Find the best Southhampton areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Top Southhampton Hotel Reviews

The Arch Convention Hotel

The Arch Convention Hotel

10/10 Excellent
"Awesome "
Julia 2-night trip
Posted 2 weeks ago
The Arch Convention Hotel

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Frequently asked questions

What is Southhampton like?

Travelers to the Southhampton neighborhood in St. Louis will be sure to enjoy their stay.

How many hotels will I find in the Southhampton area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 21 Southhampton hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Southhampton, will I receive a refund?

Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best deals in Southhampton.

Where can I learn more about changing or cancelling my trip to Southhampton?

To find more details about rescheduling or cancelling your trip to Southhampton, click here.

What can I see and do in this St. Louis neighborhood?

A few places to visit in the area around Southhampton include Miniature Museum of Greater St. Louis, Lindenwood Park, and River des Peres Greenway Trailhead. When you're sightseeing in St. Louis, Tower Grove Tennis Center and George Washington Carver Garden are also worth a stop.