Photo by Jessica Richter

Find Business Hotels in Southeast Missouri, MO

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Pick from 50 Southeast Missouri Business Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.6 out of 10, Exceptional, (1001)
"Very clean ,love the decor, rooms very large had everything u needed. "
The price is ￥18,002
per night
Jun 9 - Jun 10
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Lobby
Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, (960)
"Safety is everything to me when traveling with my family and I felt just that, safe."
The price is ￥16,809
per night
May 26 - May 27
Drury Inn & Suites Jackson MO
Lobby
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1001)
"Just a rest stop"
The price is ￥14,766
per night
May 26 - May 27
Pear Tree Inn Sikeston
Lobby
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (784)
"Everyone was very friendly and the breakfast provided was amazing!! "
The price is ￥16,876
per night
May 28 - May 29
Drury Inn & Suites Cape Girardeau
Lobby
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1000)
"We did not like the pillows. They were uncomfortable and did not conform to the shape of a person's head/neck."
The price is ￥10,265
per night
Jun 9 - Jun 10
Pear Tree Inn Cape Girardeau West
BBQ/picnic area
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1001)
"Unusual courtyard view fro rooms. Nice indoor pool. Quick friendly check in."
The price is ￥10,567
per night
May 29 - May 30
Auburn Place Hotel And Suites
Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, laptop workspace
Microtel Inn & Suites by Wyndham Sainte Genevieve
2.5 star property
8.8 out of 10, Excellent, (490)
"Comfortable clean place to stay for the night"
The price is ￥12,933
per night
Jun 10 - Jun 11
Microtel Inn & Suites by Wyndham Sainte Genevieve
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff, an IHG Hotel
3.0 star property
8.8 out of 10, Excellent, (566)
"Had a great time seeing all my family that stayed there also! Food was amazing! We ate in the banquet room because he had a huge gathering! Morning breakfast ate in the dining room! Everyone that works there are great! "
The price is ￥14,818
per night
Jun 2 - Jun 3
Holiday Inn Poplar Bluff, an IHG Hotel
Exterior
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (342)
"Staff was very helpful "
The price is ￥16,127
per night
Jun 2 - Jun 3
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Free daily full breakfast
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, (1002)
"It was a nice place to stay."
The price is ￥15,750
per night
May 26 - May 27
Best Western Plus Sikeston
Don't see what you're looking for?
See all available properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Missouri Business Hotels information

 

Business Hotels in Southeast Missouri

50

Highest price
￥18,002
Cheapest price
￥9,032
Number of guest reviews
8,721
Total number of hotels in Southeast Missouri
568

 

Recent reviews of Southeast Missouri hotels
Expedia verified reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

5/5 Excellent
"Everyone was very friendly and the breakfast provided was amazing!! "
A verified traveler stayed at Drury Inn & Suites Cape Girardeau
Posted 1 day ago
Drury Inn & Suites Cape Girardeau