Find Family Hotels in Southeast Missouri, MO

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Our top choices for Southeast Missouri family-friendly hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very Good, (1,153 reviews)
"Clean room, very friendly staff."
United States
Jordan
The price is ¥14,211
¥16,413 total
includes taxes & fees
Mar 29 - Mar 30
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,004 reviews)
"Very nice for overnight stay"
United States
Scott
The price is ¥14,966
¥17,209 total
includes taxes & fees
Mar 29 - Mar 30
Drury Inn & Suites Sikeston, MO

Best Western St. Louis Inn

Best Western St. Louis Inn
2.5 star property
St. Louis
8.2 out of 10, Very Good, (1,009 reviews)
"Clean room, breakfast was good, staff was very nice and friendly"
United States
Charles
The price is ¥11,234
¥12,916 total
includes taxes & fees
Apr 6 - Apr 7
Best Western St. Louis Inn

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very Good, (1,001 reviews)
"This was our third stay at this Motel 6. It’s a great hotel with friendly staff, clean rooms and good location. Pets stay free!"
United States
Amy
The price is ¥11,624
¥12,259 total
includes taxes & fees
Mar 24 - Mar 25
Motel 6 Poplar Bluff, MO

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,167 reviews)
"Great location, comfy and clean rooms "
United States
Nestor
The price is ¥13,399
¥15,474 total
includes taxes & fees
Mar 24 - Mar 25
Wingate by Wyndham St. Louis/Fenton Route 66

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (729 reviews)
"Very clean and staff was very nice"
United States
Nastassia
The price is ¥14,187
¥15,354 total
includes taxes & fees
Mar 29 - Mar 30
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very Good, (1,004 reviews)
"Great staff and nice accommodations "
United States
Lisa
The price is ¥9,299
¥10,587 total
includes taxes & fees
Mar 30 - Mar 31
Baymont Inn and Suites by Wyndham Farmington, MO

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,010 reviews)
"My favorite place tpstay when in the area."
United States
Jack
The price is ¥15,921
¥17,962 total
includes taxes & fees
Mar 29 - Mar 30
Drury Plaza Hotel Cape Girardeau Conference Center

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (570 reviews)
"Room was great, front desk was professional but friendly. Breakfast was excellent. Spotless — both room and lobby. "
United States
John
The price is ¥15,127
¥17,315 total
includes taxes & fees
Mar 29 - Mar 30
Holiday Inn Express & Suites Perryville by IHG

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (167 reviews)
"Nearby Mexican restaurant, clean room, pleasant staff, good breakfast choices "
United States
Larry
The price is ¥14,753
¥16,643 total
includes taxes & fees
Mar 29 - Mar 30
Fairfield Inn & Suites by Marriott Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at family-friendly hotels in Southeast Missouri

Family-friendly hotels with free breakfast in Southeast Missouri

Family-friendly hotels with pools in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southeast Missouri Hotel Reviews