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Find Luxury Hotels in Sikeston, MO

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Top Sikeston Luxury Hotels

Days Inn and Suites by Wyndham Sikeston

2.0 star property
Sikeston
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
7.2 out of 10, Good, (1007)
Sumptuous comfort awaits in this freshly renovated colonial hotel. Spacious guest rooms feature plush beds that reviewers consistently praise. A complimentary breakfast, fitness center, and library provide refined relaxation during a luxury stay.
The price is ¥9,823
¥11,195 total
includes taxes & fees
Dec 1 - Dec 2
Days Inn and Suites by Wyndham Sikeston

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau
  • Kitchen
  • Washer
  • Dryer
  • Free WiFi
  • Air conditioning
  • Outdoor Space
10.0 out of 10, Exceptional, (223)
Savor morning coffee on a private deck overlooking the majestic Mississippi River. This elegant Cape Girardeau apartment combines luxury with convenience, featuring a fully equipped gourmet kitchen, smart entertainment systems, and easy access to riverfront parks and casino entertainment.
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Housekeeping
  • 24/7 front desk
  • Extra beds/cribs
9.0 out of 10, Wonderful, (1004)
Sumptuous relaxation awaits at this immaculate retreat where attentive staff create a serene atmosphere. Spacious rooms feature LCD televisions and elegant private bathrooms, while common areas offer complimentary coffee service throughout the day in a smoke-free environment.
The price is ¥10,931
¥12,332 total
includes taxes & fees
Dec 14 - Dec 15
Pear Tree Inn Cape Girardeau Near the Medical Center

Quality Inn

2.5 star property
Cape Girardeau
  • Outdoor pool
7.2 out of 10, Good, (678)
Sophisticated comfort awaits at this tranquil hotel. Memory foam beds dressed in luxurious Egyptian cotton sheets and down comforters ensure restful slumber, while hydromassage showers offer spa-like relaxation. Staff members provide exceptional service that previous guests consistently praise.
The price is ¥9,953
¥11,228 total
includes taxes & fees
Dec 14 - Dec 15
Quality Inn

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
  • Outdoor pool
9.4 out of 10, Exceptional, (1008)
Sophisticated relaxation defines every corner of this immaculate Sikeston hotel. Guests savor complimentary gourmet breakfasts and evening manager's receptions while alternating between indoor and outdoor pools. Pristine accommodations and attentive staff ensure a luxurious experience in this centrally located haven.
The price is ¥14,055
¥16,159 total
includes taxes & fees
Dec 4 - Dec 5
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Cape Girardeau

3.0 star property
Cape Girardeau
  • Hot tub
  • Indoor pool
9.4 out of 10, Exceptional, (1005)
Soak in deluxe comfort at this recently renovated hotel featuring a pristine indoor pool and relaxing hot tub. Spacious, modern rooms provide peaceful sanctuaries after exploring nearby attractions. Evening receptions and complimentary breakfast buffets elevate the experience with quality dining options.
The price is ¥14,055
¥15,854 total
includes taxes & fees
Dec 14 - Dec 15
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Sikeston

Sikestonand its attractions for luxury travelers

Luxury travelers visiting Sikeston, Missouri, can indulge in a variety of upscale experiences that cater to their discerning tastes. Start your journey at the Sikeston Depot Museum, where you can explore the rich history of the area within a beautifully restored train depot that adds a touch of elegance to your cultural exploration. Next, take a leisurely stroll through the lush gardens of the nearby historic homes, such as the stunning Hays House, which offers a glimpse into 19th-century life and a picturesque setting for a family picnic. For an unforgettable dining experience, treat yourself to a meal at the renowned Lambert's Café, famous for its 'throwed rolls' and hearty Southern cuisine, where attentive service ensures you feel pampered throughout your meal. If you're looking for outdoor activities, head to the nearby Lake Wappapello for a day of boating or fishing, where the serene waters provide a tranquil escape from the hustle and bustle. After a day of exploration, unwind in one of Sikeston's upscale accommodations, like the Best Western Plus Sikeston, featuring modern amenities and a welcoming atmosphere that caters to families and high-end travelers alike, ensuring that every moment of your stay is comfortable and memorable.

Top Sikeston Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in Sikeston?
Use Expedia and let us help you arrange a flight to Cairo, IL (CIR-Cairo Regional) airport or Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Sikeston has to offer. During your visit, you might want to enjoy the shopping which Sikeston is known for.
When can I expect good weather in Sikeston?
Planning for the weather is a good way to make your trip to Sikeston relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's there to see and do in Sikeston?
Experience all that Sikeston has to offer when you visit Central Park, Sikeston Depot Museum, and Front Street Studio & Art Gallery. If you have a little extra time during your trip, you might want to make a stop at Stoddard County Civil War Memorial Cemetery and Hunter-Dawson State Historic Site.