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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (358 reviews)
"Excellent stay !!! Quite "
United States
Bradley
The price is ¥12,642
¥14,353 total
includes taxes & fees
Feb 12 - Feb 13
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (20 reviews)
"It was very clean and very nice place to stay, has a very home and cozy feeling walking into the room."
United States
Bryan
The price is ¥15,111
¥17,157 total
includes taxes & fees
Feb 13 - Feb 14
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (737 reviews)
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is ¥9,245
¥10,690 total
includes taxes & fees
Jan 26 - Jan 27
Baymont by Wyndham Hannibal

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"Very run down and trash around the property, but the room was clean and comfortable for our one night stop. Convenience of the location"
United States
Natalie
The price is ¥10,149
¥11,970 total
includes taxes & fees
Jan 22 - Jan 23
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (513 reviews)
"The room was dirty so dirty we left didn't spend the night there, and the smell in the building weed or something else not sure which, it was ridiculous so we went to Hannibal and stayed at the Days inn "
United States
paul
The price is ¥9,552
¥10,837 total
includes taxes & fees
Jan 15 - Jan 16
Economy Inn Wentzville

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (165 reviews)
"Great place to stay!"
United States
Sandy
The price is ¥22,651
¥31,500 total
includes taxes & fees
Jan 15 - Jan 16
Riverside Inn Hannibal

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.6 out of 10, (1,001 reviews)
"Great place to stay "
United States
Askar
The price is ¥9,729
¥11,181 total
includes taxes & fees
Feb 8 - Feb 9
Relax Inn Saint Charles

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,001 reviews)
"Pool was perfect"
United States
Jennifer
The price is ¥16,078
¥18,466 total
includes taxes & fees
Jan 20 - Jan 21
Best Western On The River

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,000 reviews)
"Room was excellent and clean"
United States
catherine
The price is ¥9,608
¥11,043 total
includes taxes & fees
Jan 19 - Jan 20
Days Inn by Wyndham St Peters/St Charles

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,004 reviews)
"Staff was great "
United States
Courtney
The price is ¥9,743
¥11,911 total
includes taxes & fees
Jan 25 - Jan 26
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Clean rooms quiet and really nice place "
United States
Vic
The price is ¥14,750
¥17,089 total
includes taxes & fees
Feb 8 - Feb 9
Sleep Inn & Suites Hannibal West

Extended Stay America Select Suites St Louis Earth City

Extended Stay America Select Suites St Louis Earth City
2.5 star property
107.1 km from Mississippi River
6.6 out of 10, (883 reviews)
"Nothing bad to say about this Hotel. Great, clean rooms and awesome staff."
United States
Charles
The price is ¥11,031
¥13,300 total
includes taxes & fees
Jan 23 - Jan 24
Extended Stay America Select Suites St Louis Earth City

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (495 reviews)
"I had to pay for my family to swim in the pool. The poll area was hazardous because there was drywall pealing off from the ceiling and around the pool. "
United States
Clarence and Kari
The price is ¥8,740
¥9,789 total
includes taxes & fees
Jan 18 - Jan 19
Baymont by Wyndham Keokuk

Super 8 by Wyndham Bowling Green

Super 8 by Wyndham Bowling Green
2.0 star property
23.9 km from Mississippi River
8.4 out of 10, Very Good, (487 reviews)
"Front desk people,...both evening 25th and morning 26th were very pleasant and helpful."
United States
Leroy
Super 8 by Wyndham Bowling Green

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.4 out of 10, (33 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is ¥10,548
¥11,914 total
includes taxes & fees
Feb 4 - Feb 5
LAKEVIEWINN

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (24 reviews)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is ¥25,007
¥28,721 total
includes taxes & fees
Jan 16 - Jan 17
Lighthouse Inn & Suites

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
103.4 km from Mississippi River
5.8 out of 10, (1,004 reviews)
"The best thing is the wonderful beds and pillows totally comfortable comfortable. Also television preferences is great for people that want to relax."
United States
Kathy
The price is ¥9,471
¥10,978 total
includes taxes & fees
Jan 15 - Jan 16
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (669 reviews)
"Room was spacious and very clean. Bed comfortable. Breakfast was great! Staff friendly and helpful. "
United States
Judy
The price is ¥12,099
¥14,375 total
includes taxes & fees
Jan 20 - Jan 21
Comfort Inn & Suites - Hannibal

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
"Overall, very nice stay"
United States
Cary
The price is ¥9,032
¥10,373 total
includes taxes & fees
Jan 19 - Jan 20
Motel 6 Hannibal, MO

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.6 out of 10, Excellent, (38 reviews)
"Host was helpful with local suggestions for things to and places to eat, as well as local history etc. Room was clean and comfortable, breakfast delicious and social. Gret spit close to downtown "
United States
Jim
The price is ¥17,050
¥19,583 total
includes taxes & fees
Jan 16 - Jan 17
Garden House Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Hampton Inn St. Louis-Downtown (At the Gateway Arch) and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.