The Best Hotels Closest to Mark Twain Boyhood Home and Museum in Hannibal for 2026

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Our top choices for Mark Twain Boyhood Home and Museum hotels

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

A compact kitchen with a refrigerator, microwave, and sink.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

1. Riverside Inn Hannibal

0.2 km from Mark Twain Boyhood Home and Museum

Janee

￥23,811

￥32,952 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

2. Lighthouse Inn & Suites

0.6 km from Mark Twain Boyhood Home and Museum

Connie

￥24,729

￥34,010 total

includes taxes & fees

Oct 24 - Oct 25

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

3. Best Western On The River

< 0.1 km from Mark Twain Boyhood Home and Museum

Wei

￥17,435

￥20,111 total

includes taxes & fees

Oct 21 - Oct 22

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A fireplace with decorative elements, framed pictures, and a vase of red flowers.

A cozy living room with a fireplace, a red armchair, a globe, and various framed pictures on the mantel.

A large, two-story house with a porch and a sign indicating 'ONE WAY'.

4. Garden House Bed and Breakfast

0.3 km from Mark Twain Boyhood Home and Museum

Debbie

￥15,213

￥17,547 total

includes taxes & fees

Oct 21 - Oct 22

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

5. Motel 6 Hannibal, MO

2.9 km from Mark Twain Boyhood Home and Museum

Jared

￥9,164

￥10,570 total

includes taxes & fees

Nov 16 - Nov 17

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted artwork.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

6. Super 8 by Wyndham Hannibal

3 km from Mark Twain Boyhood Home and Museum

Betty

￥9,788

￥11,290 total

includes taxes & fees

Oct 22 - Oct 23

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

7. Sleep Inn & Suites Hannibal West

6.6 km from Mark Twain Boyhood Home and Museum

Steve

￥18,728

￥21,790 total

includes taxes & fees

Nov 15 - Nov 16

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

A hotel entrance with a central fountain, large columns, and a clear sky.

8. Quality Inn & Suites Hannibal West

6.4 km from Mark Twain Boyhood Home and Museum

Gayle

￥11,971

￥13,927 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, a sofa, a desk, and a lamp.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

9. Comfort Inn & Suites - Hannibal

4.7 km from Mark Twain Boyhood Home and Museum

Jerry

￥12,516

￥14,914 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a dining area, kitchenette, and a door leading to a hallway.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

A hotel room with two beds, a desk, a lamp, a painting, and a carpet.

A hotel with a covered entrance, a parking lot, and a clear sky.

10. Days Inn by Wyndham Hannibal

4.9 km from Mark Twain Boyhood Home and Museum

Christian

￥10,541

￥12,159 total

includes taxes & fees

Nov 19 - Nov 20

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A hotel room with two beds, a desk, a chair, and a telephone.

A modern building with a red awning, a parking lot, and a sign indicating an entrance.

11. Howard Johnson BY Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

Debbie

￥9,415

￥10,934 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A gym with cardio equipment, mirrored walls, and a view of a Pepsi store outside.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

12. Baymont by Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

brian

￥8,758

￥10,170 total

includes taxes & fees

Oct 25 - Oct 26

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Compare popular hotels close to Mark Twain Boyhood Home and Museum

Property	Star rating	Guest rating
Riverside Inn Hannibal	9.6 Exceptional 202 reviews	View
Lighthouse Inn & Suites	8.8 Excellent 47 reviews	View
Best Western On The River	8.6 Excellent 1,010 reviews	View
Garden House Bed and Breakfast	8.2 Very good 56 reviews	View
Motel 6 Hannibal, MO	7.4 Good 1,006 reviews	View

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Comfort Inn & Suites - Hannibal

8/10 Good

"The property is in a great location for either visitors to Hannibal or travelers on U.S. 61. The front desk staff were very courteous and efficient. The breakfast was plentiful and tasty. There was ample parking. The property could use some refreshing. Carpeting was a bit worn. Plumbing in room 309 needed work on that the toilet needs to be reseated and the tub was very slow to drain. Room was clean and the beds were comfortable."

Quality Inn & Suites Hannibal West

8/10 Good

"Room was very comfortable, staff was friendly. Breakfast was great. Very clean. Nice area. The restaurant Fiddlesticks is about 300 feet from the hotel."

Best Western On The River

10/10 Excellent

"We had a beautiful view of the river. Walking distance to historic downtown. Excellent breakfast!"

Super 8 by Wyndham Hannibal

10/10 Excellent

"Clean room, quiet area at nice. Nice stay for one night on road trip."

Baymont by Wyndham Hannibal

10/10 Excellent

"The staff was great and the rooms were very clean"

Guest House with a River View, located downtown Hannibal, MO—- No Cleaning Fee

10/10 Excellent

"Great location with reserved parking close to downtown Hannibal. Host was very quick to respond to any questions."

Riverside Inn Hannibal

10/10 Excellent

"The accommodations were great! The location is perfect for touring downtown Hanibal. The only issue we had was make sure you dont choose pay in person as there is no front desk. Once the fees go through you recieve a text with the door codes."

The John Sydney House - Family and Pet Friendly Historic Home Downtown

10/10 Excellent

"Host was very responsive. We accidentally left a suit behind after staying for a wedding and we were able to arrange to pick it up during to the fact the host was very quick to respond. Would recommend to anyone."

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

10/10 Excellent

"Cute and spacious spot to stay. Great location- we were able to walk to everything we wanted to do in downtown Hannibal."

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a stop at Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savor the top-notch restaurants.

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Planters Barn Theater

8.8/10 (22 reviews)

Enjoy a show at Planters Barn Theater, a storied theater in Hannibal. While in this walkable area, you can savor the top-notch restaurants.

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Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)

You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your travels to Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

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Bluff City Theater

7.6/10 (5 reviews)

Enjoy a show at Bluff City Theater, a theater with a story to tell in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

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Molly Brown Museum and Home

8.4/10 (64 reviews)

You can browse the exhibits at Molly Brown Museum and Home, a museum with a story of its own, during your travels to Hannibal. While in this walkable area, you can savor the top-notch restaurants.

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Lovers Leap

8.8/10 (171 reviews)

Find out about the history of Hannibal with a stop at Lovers Leap. While in this walkable area, you can savor the top-notch restaurants.

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Riverview Park

You can find out about the history of Hannibal with a visit to Riverview Park. While in this family-friendly area, you can savor the top-notch restaurants.

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Sodalis Nature Preserve

Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

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Frequently asked questions

What's the area like around Mark Twain Boyhood Home and Museum?

Mark Twain Boyhood Home and Museum is located in a welcoming area of Hannibal known for its array of dining options. If you're looking for a convenient place to stay, check out the 40 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Mark Twain Boyhood Home and Museum?

Adjacent to Mark Twain Boyhood Home and Museum, Best Western On The River is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Lighthouse Inn & Suites and Garden House Bed and Breakfast.

How many hotels are there near Mark Twain Boyhood Home and Museum?

Expedia has 40 hotels and other accommodations within a mile from Mark Twain Boyhood Home and Museum.

If I need to cancel the hotel reservation for my stay near Mark Twain Boyhood Home and Museum, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals close to Mark Twain Boyhood Home and Museum.

Where can I learn more about changing or cancelling my trip in the area near Mark Twain Boyhood Home and Museum?

To access more information about changing or cancelling your stay near Mark Twain Boyhood Home and Museum, go to https://www.expedia.com/service/.

What can I see and do near Mark Twain Boyhood Home and Museum?

You'll want to browse the exhibits at Jim's Journey: The Huck Finn Freedom Center and Molly Brown Museum and Home. Mark Twain Memorial Lighthouse, Rockcliffe Mansion, and Mark Twain Cave are notable landmarks to explore if you're in the area. You can enjoy live performances at Bluff City Theater and Planters Barn Theater.

Find hotels near Mark Twain Boyhood Home and Museum, Hannibal from ￥10,170

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Our top choices for Mark Twain Boyhood Home and Museum hotels

1. Riverside Inn Hannibal

2. Lighthouse Inn & Suites

3. Best Western On The River

4. Garden House Bed and Breakfast

5. Motel 6 Hannibal, MO

6. Super 8 by Wyndham Hannibal

7. Sleep Inn & Suites Hannibal West

8. Quality Inn & Suites Hannibal West

9. Comfort Inn & Suites - Hannibal

10. Days Inn by Wyndham Hannibal

11. Howard Johnson BY Wyndham Hannibal

12. Baymont by Wyndham Hannibal

Compare popular hotels close to Mark Twain Boyhood Home and Museum

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Comfort Inn & Suites - Hannibal

Quality Inn & Suites Hannibal West

Best Western On The River

Super 8 by Wyndham Hannibal

Baymont by Wyndham Hannibal

Guest House with a River View, located downtown Hannibal, MO—- No Cleaning Fee

Riverside Inn Hannibal

The John Sydney House - Family and Pet Friendly Historic Home Downtown

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

Planters Barn Theater

Jim's Journey: The Huck Finn Freedom Center

Bluff City Theater

Molly Brown Museum and Home

Lovers Leap

Riverview Park

Sodalis Nature Preserve

Frequently asked questions