Northeast Missouri, MO
Travel Guide
Visit Northeast Missouri
Where to stay in Northeast Missouri
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Room was very nice, clean, staff was great!
Reviewed on Jan 5, 2026
Clayton Plaza Hotel & Extended Stay
The room was very cozy and welcoming. The staff was great and friendly from checking in to the breakfast host to checking out.
Reviewed on Jan 5, 2026
21C Museum Hotel St Louis
Great staff and very clean room.
Reviewed on Jan 5, 2026
White House at Grand Central
Great place
Reviewed on Dec 27, 2025
The St. Charles Guest House, lovely historic home, fun for families and groups
The house was incredible! Clean, cozy yet spacious and a perfect location 1/2 block from the historic district. Shops, eating and walking paths all just a few steps from our doorstep!
Reviewed on Nov 18, 2025
Luxury 2BEDROOM LOFT near Bush Stadium
Great location for baseball and hockey fans!
Reviewed on Dec 23, 2025
Check Northeast Missouri hotel availability
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
City Museum
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
St. Louis University
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theater scene.
Things to do
Tom's Town Distillery Tour and Tasting
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
Kansas City: Country Club Plaza Escape Game
Kansas City Scavenger Hunt: Fountains, Fun & Hidden Finds
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- St. Louis Union Station
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- Barnes Jewish Hospital
- City Museum
- Six Flags St. Louis
- Hollywood Casino Amphitheatre
- Fox Theater
- Anheuser-Busch Brewery
- Magic House - St. Louis Children's Museum
- Missouri Botanical Gardens and Arboretum
- Route 66 State Park
- St. Louis Aquarium at Union Station
- Grant's Farm
- St. Louis Science Center
