Historic Main Street
Visit Historic Main Street
Plan a trip to see Historic Main Street
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Reviewed on Aug 25, 2025
Hilton St. Louis Airport
Reviewed on Aug 23, 2025
Popular places to visit
Frontier Park
You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this family-friendly area.
First Missouri State Capitol Historic Site
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and great live music in this family-friendly area.
Missouri Artists on Main
You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
SSM Health St. Joseph Hospital
Though SSM Health St. Joseph Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Charles while you are here.
Lewis & Clark Boathouse and Nature Center
You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.
Frenchtown Heritage Museum
You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
Best Lodging Options Near Historic Main Street
Check availability on hotels close to Historic Main Street
Hollywood Casino & Hotel St. Louis
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District
The St. Charles Guest House, lovely historic home, fun for families and groups
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
HUGE 2 bedroom unit on Main Street
Luxurious couples retreat just steps from Historic Main Street in St. Charles!
The Otter Suite at Divine Otter
The Fox Suite at Divine Otter
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Vacations and getaways similar to Historic Main Street
- Other Hotels near Historic Main Street, St. Charles Historic District
- Hotels near popular St. Louis Attractions
- More Hotel Options in Historic Main Street
- Busch Stadium
- St. Louis Union Station
- Gateway Arch
- Washington University in St. Louis
- St. Louis Zoo
- Six Flags St. Louis
- City Museum
- Hollywood Casino Amphitheatre
- Barnes Jewish Hospital
- Fox Theater
- Grant's Farm
- Missouri Botanical Gardens and Arboretum
- Anheuser-Busch Brewery
- Route 66 State Park
- Magic House - St. Louis Children's Museum
- 3BR Historic St. Charles, MO-Walking distance to Main Street
- The Owl Suite at Divine Otter
- The Buck Suite at Divine Otter
- The Wild West Getaway- 204-1
- The Bear Suite at Divine Otter
- Scenic South Main Apartment with Breathtaking Views for 3 Guests
- The Hare Suite at Divine Otter
- Walking distance to Historic Main Street, St. Charles, MO
- Western-Themed 2-Bedroom Hideout for Outlaws 204-2
- Relaxing South Main Apartment with Modern Comforts
- Best Western Plus The Charles Hotel