Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri

Find hotels in Louisiana, MO from ¥9,978

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Our top choices for Louisiana hotels

1. River's Edge Motel

River's Edge Motel
2.0 star property
Louisiana
9.0 out of 10, Wonderful, (367 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
United States
Brent
The price is ¥12,819
¥14,554 total
includes taxes & fees
Jun 15 - Jun 16
River's Edge Motel

2. The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
Louisiana
9.4 out of 10, Exceptional, (25 reviews)
"Very nice place to stay loved the brick walls and wood floors leading up to the rooms"
United States
Gary
The price is ¥17,026
¥19,330 total
includes taxes & fees
Jun 22 - Jun 23
The Eagles Nest Inn

3. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
Hannibal
7.4 out of 10, Good, (1,010 reviews)
"Nice staff, good parking, clean room."
United States
Susan
The price is ¥8,651
¥9,978 total
includes taxes & fees
Jun 21 - Jun 22
Motel 6 Hannibal, MO

4. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
Hannibal
8.0 out of 10, Very Good, (1,012 reviews)
"Parking was easy and safe, when the staff was available, they were courteous, and breakfast was good."
United States
Dan
The price is ¥12,042
¥14,011 total
includes taxes & fees
Jul 12 - Jul 13
Quality Inn & Suites Hannibal West

5. Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
Hannibal
7.2 out of 10, Good, (1,004 reviews)
"Property was clean and staff was friendly."
United States
Etta
The price is ¥10,658
¥12,294 total
includes taxes & fees
Jun 28 - Jun 29
Super 8 by Wyndham Hannibal

6. Rodeway Inn Pittsfield

Rodeway Inn Pittsfield
2.0 star property
Pittsfield
6.8 out of 10, (136 reviews)
"Staff is great and id stay again "
United States
Thor
The price is ¥9,518
¥10,468 total
includes taxes & fees
Jun 28 - Jun 29
Rodeway Inn Pittsfield

7. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
Hannibal
7.4 out of 10, Good, (250 reviews)
"A good place to stay in Hannibal."
United States
Marcia
The price is ¥10,528
¥12,144 total
includes taxes & fees
Jun 16 - Jun 17
Days Inn by Wyndham Hannibal

8. William Watson Hotel

William Watson Hotel
3.0 star property
Pittsfield
9.2 out of 10, Wonderful, (361 reviews)
"Great location, restaurant downstairs, friendly staff, microwaves and refrigerator in room, historic significance "
United States
Druann
The price is ¥13,007
¥14,306 total
includes taxes & fees
Jul 5 - Jul 6
William Watson Hotel

9. Monroe Street Suites

Monroe Street Suites
2.5 star property
Pittsfield
9.6 out of 10, Exceptional, (65 reviews)
"A unique luxurious find for rest and respite on a long trip home. Would stay here again, without any hesitation!"
United States
Donna
The price is ¥15,663
¥17,227 total
includes taxes & fees
Jun 15 - Jun 16
Monroe Street Suites

10. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1,002 reviews)
"Good breakfast"
United States
Neah
The price is ¥19,637
¥22,848 total
includes taxes & fees
Jun 28 - Jun 29
Sleep Inn & Suites Hannibal West

11. Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
Hannibal
7.4 out of 10, Good, (168 reviews)
"The room was clean . The staff was helpful on things to do in the area. It was a very relaxing and the town was beautiful"
United States
Samantha
The price is ¥9,895
¥11,493 total
includes taxes & fees
Jun 21 - Jun 22
Howard Johnson BY Wyndham Hannibal

12. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
Hannibal
7.6 out of 10, Good, (705 reviews)
"As always the beds at comfort inn are so comfortable. Enjoyed our stay."
United States
Tracey
The price is ¥13,853
¥16,460 total
includes taxes & fees
Jul 12 - Jul 13
Comfort Inn & Suites - Hannibal

13. Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
Hannibal
6.4 out of 10, (774 reviews)
"The staff were very friendly and helpful, The breakfast was probably the best we had experienced at any hotel where we have stayed. If we pass through the area again, we will likely choose to stay there again."
United States
Carol
The price is ¥10,095
¥11,725 total
includes taxes & fees
Jun 15 - Jun 16
Baymont by Wyndham Hannibal

14. Best Western On The River

Best Western On The River
2.5 star property
Hannibal
8.6 out of 10, Excellent, (1,016 reviews)
"Clean rooms, decent breakfast"
United States
Christina
The price is ¥17,689
¥20,403 total
includes taxes & fees
Jun 28 - Jun 29
Best Western On The River

15. Green Acres Hotel

Green Acres Hotel
2.5 star property
Pittsfield
8.8 out of 10, Excellent, (147 reviews)
"Good place to stay!"
United States
Riley
The price is ¥18,878
¥20,762 total
includes taxes & fees
Jun 16 - Jun 17
Green Acres Hotel

16. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
Hannibal
9.4 out of 10, Exceptional, (178 reviews)
"Surprisingly fun property, clean, quiet (except for the train whistles). Hot tub was a great addition! Close to downtown fun! Would stay here again!"
United States
Michael
The price is ¥25,802
¥35,306 total
includes taxes & fees
Jun 15 - Jun 16
Riverside Inn Hannibal

17. Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
Hannibal
8.4 out of 10, Very Good, (43 reviews)
"Very welcoming hosts, they went the extra mile and had a very comfortable bed! There were lots of cool antiques and they knew a lot of history on the home itself. We would recommend staying here again. "
United States
Andy Nicole
The price is ¥17,086
¥19,711 total
includes taxes & fees
Jun 19 - Jun 20
Garden House Bed and Breakfast

18. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
9.0 out of 10, Wonderful, (30 reviews)
"Fun themed rooms."
United States
Kelly
The price is ¥27,378
¥37,125 total
includes taxes & fees
Jun 15 - Jun 16
Lighthouse Inn & Suites
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Learn more about Louisiana

Like rivers? Get away to relaxing Louisiana!

Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri

Top Louisiana Hotel Reviews

More cheap stays in Louisiana

Frequently asked questions

Where is the best place to stay in Louisiana?
Based on our traveler data, The Eagles Nest Inn is one of the top choices for your stay. This inn is a short 3-minute walk from Mississippi River, and it offers a restaurant and free parking. River's Edge Motel is another good option for your trip. See all available top hotels, or vacation rentals in Louisiana.
What are some of the best vacation rentals in Louisiana?
The Yellow Rose Historic Home: Visitors like this Louisiana vacation home rental. It offers a selection of games, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Louisiana.
If I need to cancel my hotel reservation in Louisiana, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Louisiana.
Where can I learn more about changing or cancelling my trip to Louisiana?
To access more information about picking new dates or cancelling your trip to Louisiana, go to https://www.expedia.com/service/.
What's the best hotel for a couple visiting Louisiana?
Come see what our Historical town has to offer! is a favorite B&B for couples, and features in-room kitchenettes and private patios. See all romantic hotels in Louisiana.
What's the best pet-friendly hotel in Louisiana?
River's Edge Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Louisiana.
What are some hotels with pools in Louisiana?
Quality Inn & Suites Hannibal West: Features a snack bar/deli, an indoor pool, and buffet. Best Western On The River and Comfort Inn & Suites - Hannibal are two additional hotels with an onsite pool. View all hotels with pools in Louisiana.
What's the best accommodation near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What is staying in Louisiana like?
Visitors to Louisiana are sure to enjoy the riverfront. This city also attracts tourists with its welcoming and relaxing setting. In Louisiana, there are 5 hotels and other accommodations to choose from. Find out more about Louisiana.
What should I do while I'm visiting Louisiana?
A favorite place to visit is Mississippi River. You'll also find Clarksville Riverfront Park and Clarksville State Game Refuge in the area. Check out what more to see and do in Expedia's Louisiana guide.
What's the seasonal weather like in Louisiana?
The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. Average annual precipitation for Louisiana is 49 inches.