Find hotels in Louisiana, MO from ¥8,121

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 83 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

River's Edge Motel

2.0 star property
9.0 out of 10, Wonderful, (332)
"Great clean place to stay with friendly staff"
The price is ¥11,815
¥13,414 total
includes taxes & fees
Jul 29 - Jul 30
River's Edge Motel

The Eagles Nest Inn

3.0 star property
9.2 out of 10, Wonderful, (7)
"It was very clean and very nice place to stay, has a very home and cozy feeling walking into the room."
The price is ¥12,866
¥14,609 total
includes taxes & fees
Aug 6 - Aug 7
The Eagles Nest Inn

Monroe Street Suites

2.5 star property
9.6 out of 10, Exceptional, (56)
"Definitely one of the best hotels I’ve ever stayed in. Super quiet, clean, convenient, it’s located in town, which there were plenty of shopping and food options. Overall, I would definitely recommend this hotel. And I will be staying there again in the future."
The price is ¥23,846
¥26,227 total
includes taxes & fees
Jul 29 - Jul 30
Monroe Street Suites

William Watson Hotel

3.0 star property
9.0 out of 10, Wonderful, (326)
"Very quaint. "
The price is ¥10,923
¥12,014 total
includes taxes & fees
Aug 28 - Aug 29
William Watson Hotel

Green Acres Hotel

2.5 star property
8.6 out of 10, Excellent, (133)
"Wonderful stay - was staying with a number of family members and it all worked out"
The price is ¥17,575
¥19,330 total
includes taxes & fees
Jul 29 - Jul 30
Green Acres Hotel

Rodeway Inn

2.0 star property
7.0 out of 10, Good, (118)
"They really should attach the drain cover to the shower drain. Somebody could get seriously injured. Being a tile guy, looking around really had me laughing at the workmanship. The manager was a pretty cool guy, the room was fine, air conditioner worked great. Never went to the continental breakfast, i did see some little Debbie items"
The price is ¥9,172
¥10,087 total
includes taxes & fees
Aug 3 - Aug 4
Rodeway Inn

Riverside Inn Hannibal

2.5 star property
9.4 out of 10, Exceptional, (129)
"Excellent service, room, and location."
The price is ¥19,154
¥27,088 total
includes taxes & fees
Aug 18 - Aug 19
Riverside Inn Hannibal

Best Western On The River

2.5 star property
8.6 out of 10, Excellent, (1009)
"Excellent and friendly staff!! Good breakfast as well!"
The price is ¥18,755
¥21,540 total
includes taxes & fees
Jul 29 - Jul 30
Best Western On The River

Garden House Bed and Breakfast

2.0 star property
8.6 out of 10, Excellent, (22)
"A beautiful 19th century mansion, decorated in period. Quiet and comfortable."
The price is ¥14,380
¥16,515 total
includes taxes & fees
Aug 8 - Aug 9
Garden House Bed and Breakfast

Lighthouse Inn & Suites

4.0 star property
9.0 out of 10, Wonderful, (14)
"Location is excellent! Close to historic downtown but far enough away to be quiet and peaceful! Very clean and decor is wonderful!"
The price is ¥24,304
¥27,912 total
includes taxes & fees
Jul 29 - Jul 30
Lighthouse Inn & Suites

Motel 6 Hannibal, MO

2.0 star property
7.4 out of 10, Good, (1006)
"Economical and comfortable, staff is anxious to serve. "
The price is ¥8,121
¥9,326 total
includes taxes & fees
Jul 31 - Aug 1
Motel 6 Hannibal, MO

Super 8 by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (1006)
"Nice place, easy to find. "
The price is ¥9,540
¥10,959 total
includes taxes & fees
Aug 3 - Aug 4
Super 8 by Wyndham Hannibal

Comfort Inn & Suites - Hannibal

2.5 star property
7.6 out of 10, Good, (616)
"Great area and clean facilities"
The price is ¥14,488
¥17,082 total
includes taxes & fees
Aug 3 - Aug 4
Comfort Inn & Suites - Hannibal

Baymont by Wyndham Hannibal

2.5 star property
6.2 out of 10, (682)
"Very good breakfast, nice heated indoor pool, good exercise room, friendly staff. Highly recommended."
The price is ¥10,043
¥11,613 total
includes taxes & fees
Jul 29 - Jul 30
Baymont by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (182)
"I always stay here and have a very good experience"
The price is ¥10,043
¥11,535 total
includes taxes & fees
Jul 30 - Jul 31
Days Inn by Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2.0 star property
7.0 out of 10, Good, (128)
"Its a fine place. A bit outdated and worn but it met our needs and was clean."
The price is ¥9,262
¥10,708 total
includes taxes & fees
Jul 30 - Jul 31
Howard Johnson BY Wyndham Hannibal

Quality Inn & Suites Hannibal

2.5 star property
7.8 out of 10, Good, (993)
"Good location, very welcoming, room was comfortable & breakfast was tasty. "
The price is ¥15,586
¥17,901 total
includes taxes & fees
Aug 3 - Aug 4
Quality Inn & Suites Hannibal

Sleep Inn & Suites

2.5 star property
9.6 out of 10, Exceptional, (1011)
"Great stay!"
The price is ¥17,147
¥19,865 total
includes taxes & fees
Aug 17 - Aug 18
Sleep Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Louisiana

Like rivers? Get away to relaxing Louisiana!

Top Louisiana Hotel Reviews

Frequently asked questions

Where is the best place to stay in Louisiana?

Based on our traveler data, The Eagles Nest Inn is one of the top choices for your stay. This inn is a short 3-minute walk from Mississippi River, and it offers a restaurant and free parking. River's Edge Motel is another good option for your trip. See all available top hotels, or vacation rentals in Louisiana.

What are some of the best vacation rentals in Louisiana?

The Yellow Rose Historic Home: Visitors like this Louisiana vacation home rental. It offers a selection of games, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Louisiana.

If I need to cancel my hotel reservation in Louisiana, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Louisiana.

Where can I learn more about changing or cancelling my trip to Louisiana?

To access more information about picking new dates or cancelling your trip to Louisiana, go to https://www.expedia.com/service/.

What's the best hotel for a couple visiting Louisiana?

Come see what our Historical town has to offer! is a favorite B&B for couples, and features in-room kitchenettes and private patios. See all romantic hotels in Louisiana.

What's the best pet-friendly hotel in Louisiana?

River's Edge Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Louisiana.

What's the best hotel to stay near The Eagle's Nest Winery?

River's Edge Motel is one of the top choices for your stay based on our traveler data, and this property offers free WiFi and free parking. It's located just a short 0.4 mi (0.6 km) from The Eagle's Nest Winery. Other good choices in the area include Super 8 by Wyndham Bowling Green and Knights Inn Pittsfield.

What are some hotels with pools in Louisiana?

Baymont by Wyndham Hannibal: Offers a health club, an indoor pool, and full. Best Western On The River and Quality Inn & Suites Hannibal are two additional hotels with an onsite pool. View all hotels with pools in Louisiana.

What's the best accommodation near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What is staying in Louisiana like?

Visitors to Louisiana are sure to enjoy the riverfront. This city also attracts tourists with its welcoming and relaxing setting. In Louisiana, there are 6 hotels and other accommodations to choose from. Find out more about Louisiana.

What should I do while I'm visiting Louisiana?

A couple of favorite places to visit are Mississippi River and The Eagle's Nest Winery. You'll also find Clarksville State Game Refuge and Clarksville Riverfront Park in the area. Check out what more to see and do in Expedia's Louisiana guide.

What's the seasonal weather like in Louisiana?

The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 35°F. Average annual precipitation for Louisiana is 49 inches.