Photo by Ryan Coleman

Find hotels in Sikeston, MO from ¥8,878

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Compare 277 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1008)
"Clean room, great location and friendly staff"
United States
Mark
The price is ¥14,420
¥16,579 total
includes taxes & fees
Nov 18 - Nov 19
Drury Inn & Suites Sikeston, MO

Hampton Inn Sikeston

2.5 star property
Sikeston
8.8 out of 10, Excellent, (423)
"Nice property and friendly staff."
United States
Nancy
The price is ¥14,606
¥16,537 total
includes taxes & fees
Nov 30 - Dec 1
Hampton Inn Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1004)
"Everything was clean, staff was friendly "
United States
Matthew
The price is ¥11,812
¥13,578 total
includes taxes & fees
Nov 15 - Nov 16
Pear Tree Inn Sikeston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
Sikeston
7.2 out of 10, Good, (1004)
"A great stay in every aspect. "
United States
Gertrude
The price is ¥9,650
¥10,997 total
includes taxes & fees
Nov 16 - Nov 17
Days Inn and Suites by Wyndham Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very Good, (704)
"Very quiet and comfortable "
United States
Lana
The price is ¥9,094
¥10,365 total
includes taxes & fees
Nov 11 - Nov 12
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Best Western Plus Sikeston

2.5 star property
Sikeston
8.4 out of 10, Very Good, (1003)
"Very convenient and great breakfast "
United States
Duwaine
The price is ¥12,909
¥14,715 total
includes taxes & fees
Nov 16 - Nov 17
Best Western Plus Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
Sikeston
8.6 out of 10, Excellent, (438)
"staff was friendly nothing to crazy about this hotel "
United States
Isaac
The price is ¥15,495
¥17,543 total
includes taxes & fees
Nov 21 - Nov 22
Holiday Inn Express & Suites Sikeston Southwest by IHG

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
Sikeston
9.2 out of 10, Wonderful, (31)
"Very clean and comfortable room. "
United States
Roxanne
The price is ¥15,495
¥17,544 total
includes taxes & fees
Nov 20 - Nov 21
Fairfield Inn & Suites by Marriott Sikeston

Country Yard Inn and Suite

2.0 star property
Sikeston
6.8 out of 10, (114)
"The property was well kept but lacked convenience of food and computer."
United States
holly s
The price is ¥7,462
¥8,878 total
includes taxes & fees
Nov 14 - Nov 15
Country Yard Inn and Suite

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1009)
"Nice place"
United States
Daniel
The price is ¥13,499
¥14,272 total
includes taxes & fees
Nov 11 - Nov 12
Drury Inn & Suites Jackson MO

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
Sikeston
6.6 out of 10, (559)
"Staff is always so nice and rooms are always clean. I have stayed here several times over the years and always come back to it when traveling through. "
United States
Laura
The price is ¥9,619
¥10,962 total
includes taxes & fees
Nov 16 - Nov 17
Super 8 by Wyndham Sikeston/Miner Area

Comfort Inn & Suites Sikeston I-55

2.5 star property
Sikeston
8.4 out of 10, Very Good, (277)
"Room was clean, breakfast was very good. "
United States
Connie
The price is ¥12,910
¥14,715 total
includes taxes & fees
Dec 7 - Dec 8
Comfort Inn & Suites Sikeston I-55

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (648)
"Stayed on our way south for vacation. It was a clean nice place to stay. "
United States
Joel
The price is ¥12,910
¥13,972 total
includes taxes & fees
Nov 13 - Nov 14
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

TownePlace Suites by Marriott Sikeston

3.0 star property
Sikeston
8.4 out of 10, Very Good, (5)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is ¥18,564
¥21,019 total
includes taxes & fees
Nov 16 - Nov 17
TownePlace Suites by Marriott Sikeston

Pear Tree Inn Cape Girardeau West

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1006)
"Staff very accommodating and everything was very clean!"
United States
Dericka
The price is ¥10,738
¥12,114 total
includes taxes & fees
Nov 16 - Nov 17
Pear Tree Inn Cape Girardeau West

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1006)
"Clean room and amenities were great"
United States
Crystal
The price is ¥14,267
¥16,096 total
includes taxes & fees
Nov 20 - Nov 21
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Cape Girardeau

3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. "
United States
Sandra
The price is ¥13,806
¥15,573 total
includes taxes & fees
Nov 30 - Dec 1
Drury Inn & Suites Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1005)
"Always enjoy our stay. Staff is very friendly, especially at breakfast! "
United States
Paul
The price is ¥10,738
¥12,114 total
includes taxes & fees
Nov 16 - Nov 17
Pear Tree Inn Cape Girardeau Near the Medical Center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1005)
"Clean and welcoming. Tyler at the front desk for check in was engaging and friendly. He’s a gem!!"
United States
Penny
The price is ¥15,189
¥17,134 total
includes taxes & fees
Nov 30 - Dec 1
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (605)
"Staff was great! Room was nice. "
United States
Lana
The price is ¥8,476
¥9,407 total
includes taxes & fees
Nov 11 - Nov 12
Super 8 by Wyndham Charleston/Sikeston East MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Stay near popular Sikeston attractions

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

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Frequently asked questions

Where is the best place to stay in Sikeston?
Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in Sikeston.
What are some of the best vacation rentals in Sikeston?
On the Wine Trail - Minutes to Giant City, Shawnee Forest, SIU - Amazing Shower: This vacation home rental outside of Sikeston offers a patio, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Make the most of the books in this rental home to help you unwind. See all vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
Where can I learn more about changing or cancelling my trip to Sikeston?
For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.
What's the best hotel for a family vacation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.
What is the top LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best pet-friendly accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Days Inn and Suites by Wyndham Sikeston. See more pet-friendly hotel accommodations in Sikeston.
Where is the best hotel to stay close to Central Park?
Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.
What about the best place to stay close to Sikeston Depot Museum?
One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.
What are some accommodations with pools in Sikeston?
Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.
What's the best place to stay near Barkley Regional Airport (PAH)?
Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.
What is staying in Sikeston like?
Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.
What are the top places to visit in Sikeston?
A couple of favorite places to visit are Central Park and Sikeston Depot Museum. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.
What's the seasonal weather like in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.

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