New Madrid, MO

Travel Guide

A cannon on a brick platform by a river, with a steamboat in the background.
A river with a dam, surrounded by greenery and a clear sky.
A tree-lined landscape with a river and fields.
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

New Madrid MO
The price is ￥31,790 per night from Aug 28 to Aug 29
￥31,790
￥58,681 total
Aug 28 - Aug 29
includes taxes & fees
Stay at this vacation home in New Madrid. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions New Madrid Historical Museum and River Ridge ...
10/10 Exceptional! (1 review)
"The host was very quick to respond and so great to work with for on our stay."

Reviewed on Nov 11, 2025

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
The price is ￥16,704 per night from Aug 30 to Aug 31
￥16,704
￥18,913 total
Aug 30 - Aug 31
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Sikeston Southwest by IHG
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is ￥16,292 per night from Sep 13 to Sep 14
￥16,292
￥18,447 total
Sep 13 - Sep 14
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
Hampton Inn Sikeston
See all 57 properties in New Madrid
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

New Madrid MO
Stay at this vacation home in New Madrid. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions New Madrid Historical Museum and River Ridge ...
10/10 Exceptional! (1 review)
"The host was very quick to respond and so great to work with for on our stay."

Reviewed on Nov 11, 2025

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Duck Hunting, Fishing or Relaxing Family Vacation

Duck Hunting, Fishing or Relaxing Family Vacation

Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (242 reviews)
"This property was one of the cleanest we have ever stayed at. They had one of the nicest coffee stations I have ever seen in a VRBO and everything you could need !"

Reviewed on Aug 11, 2026

Duck Hunting, Fishing or Relaxing Family Vacation
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (11 reviews)
"Great place to stay"

Reviewed on Jul 27, 2026

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
See all properties in New Madrid
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular New Madrid attractions

Hunter-Dawson State Historic Site

7.6/10 (13 reviews)
You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your travels to New Madrid. Amble around the area's parks or experience its museums.
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