A cannon on a brick platform by a river, with a steamboat in the background.

Find hotels in New Madrid, MO from ￥11,971

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Check prices for these dates

This weekend
Jul 31 - Aug 2
Next weekend
Aug 7 - Aug 9

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Our top choices for New Madrid hotels

Exterior

1. Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (597 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
United States
Brandi
The price is ￥16,884
￥19,117 total
includes taxes & fees
Aug 13 - Aug 14
Hampton Inn Sikeston
Exterior

2. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (488 reviews)
"Very clean room breakfast was good"
United States
michael
The price is ￥14,844
￥16,807 total
includes taxes & fees
Aug 30 - Aug 31
Holiday Inn Express & Suites Sikeston Southwest by IHG
Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout drapes, WiFi (free)

3. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very Good, (69 reviews)
"Clean room, The receptionist very friendly, good parking."
United States
Temera
The price is ￥13,216
￥15,097 total
includes taxes & fees
Aug 2 - Aug 3
Super 8 By Wyndham Marston
Standard Room, 2 Double Beds, Non Smoking | Blackout drapes, iron/ironing board (on request), WiFi (free)

4. Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (502 reviews)
"The lake view was beautiful and staff was amazing"
United States
Richard
The price is ￥9,736
￥12,088 total
includes taxes & fees
Aug 24 - Aug 25
Reelfoot Lake Inn
Property amenity

5. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (101 reviews)
"Perfect last minute stop on our road trip Very clean, well maintained and pleasant staff"
United States
Dwain
The price is ￥17,557
￥19,880 total
includes taxes & fees
Aug 20 - Aug 21
Fairfield Inn & Suites by Marriott Sikeston
WiFi (free), bed sheets

6. Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
6.0 out of 10, (127 reviews)
"OLD FACILITY, NEED TO FIX SOMETHINGS."
United States
Bosup
The price is ￥9,636
￥11,971 total
includes taxes & fees
Aug 30 - Aug 31
Travel Inn Marston I-55 by Hotel O
Property amenity

7. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is ￥17,397
￥19,698 total
includes taxes & fees
Aug 23 - Aug 24
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular New Madrid attractions

River Ridge Winery

8.4/10 (15 reviews)
Sip handcrafted wines in a century-old farmhouse atop the Mississippi River hills. Wander through estate vineyards or enjoy fresh meals on the scenic grounds of this Missouri wine destination.
See properties

Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic story of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

See all hotels in New Madrid
A cannon on a brick platform by a river, with a steamboat in the background.

Top New Madrid Hotel Reviews

Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"Everything was good"
Jennifer 2-night trip
Posted 2 days ago
Hampton Inn Sikeston

More cheap stays in New Madrid

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O

301 Route Ad Marston MO
The price is ￥9,636 per night from Aug 30 to Aug 31
￥9,636
￥11,971 total
Aug 30 - Aug 31
includes taxes & fees

Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 18.9 mi (30.4 km) from the heart of New Madrid, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Holiday Inn Express & Suites Sikeston Southwest by IHG and New Orleans Inn Portageville. See all available top hotels, or vacation rentals in New Madrid.
What are some of the best vacation home rentals that New Madrid has to offer?
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!: This New Madrid vacation home rental offers a garden, a selection of games, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
Where can I learn more about changing or cancelling my trip to New Madrid?
For additional details about updating your trip to New Madrid or cancelling it, head over to our customer service page.
What's the best hotel to stay with easy access to New Madrid Historical Museum?
Travel Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. You'll find it 6.8 mi (10.9 km) from New Madrid Historical Museum. Other good options around the area include Reelfoot Lake Inn and Lodge that sleeps 16! Ideal for Fishermen, Family reunions, Hunters and Tourist!.
What about the best place to stay near Hunter-Dawson State Historic Site?
One of the top choices for your stay is Travel Inn, located 7.2 mi (11.6 km) from Hunter-Dawson State Historic Site, and this hotel offers free breakfast and free parking. Reelfoot Lake Inn and Lodge that sleeps 16! Ideal for Fishermen, Family reunions, Hunters and Tourist! are other good choices within the area.
What's the best accommodation near Cairo Regional Airport (CIR)?
Quality Inn Cairo I-57 is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.1 mi (3.3 km) from Cairo Regional Airport.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer including the parks and museums. There are 59 hotels and other accommodations in the surrounding area. Find out more about New Madrid.
What are the top places to visit in New Madrid?
Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your agenda are Mississippi River and River Ridge Winery. Check out what more to see and do in Expedia's New Madrid guide.
What's the weather like in New Madrid?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 42°F. Average annual precipitation for New Madrid is 60 inches.