Find hotels in New Madrid, MO from ¥10,259

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Our top choices for New Madrid hotels

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
7.8 out of 10, Good, (39)
This hotel in Marston offers complimentary perks including daily full breakfast served between 6:00 AM and 9:00 AM, WiFi, and self parking. Conveniently located for travelers exploring the area.

"Great hotel, great staff"
United States
Dmitry
The price is ¥8,982
¥10,259 total
includes taxes & fees
Dec 17 - Dec 18
Super 8 By Wyndham Marston

Travel Inn

Travel Inn
2.5 star property
Marston
6.0 out of 10, (116)
This welcoming Marston hotel offers complimentary on-the-go breakfast to start your day right. Take advantage of free WiFi to stay connected and enjoy the convenience of complimentary self parking during your countryside stay.

"Had a great time loved it "
United States
Shyianne
Travel Inn

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (444)
Take a refreshing dip in the indoor pool or maintain your routine at the fitness center. Free breakfast, WiFi, and parking enhance your stay. Central Park and Sikeston Depot Museum are just moments away from this welcoming retreat.

"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is ¥14,833
¥16,795 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
Discover comfort at this Sikeston hotel with an indoor pool and fitness center. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby Central Park and Sikeston Depot Museum. Guests consistently praise the helpful staff and immaculate rooms.

"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
The price is ¥14,490
¥16,407 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express & Suites Sikeston Southwest by IHG

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (40)
This business-friendly hotel offers an indoor pool, restaurant, and complimentary breakfast. Located near Sikeston Depot Museum, guests enjoy free WiFi and parking while exploring local attractions.

"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is ¥15,737
¥17,818 total
includes taxes & fees
Dec 21 - Dec 22
Fairfield Inn & Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.0 out of 10, Wonderful, (8)
Set near Central Park and Sikeston Depot Museum, this business-friendly hotel offers a refreshing indoor pool and convenient daily breakfast. Enjoy well-appointed accommodations with complimentary WiFi and self parking just 32 minutes from Cairo Regional Airport.

"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is ¥18,386
¥20,818 total
includes taxes & fees
Dec 21 - Dec 22
TownePlace Suites by Marriott Sikeston

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (459)
"Nice and quiet but there were bugs in the room the fridge didn't keep things cold and the A/C didn't keep the room cool. Great place if you're a fisherman."
United States
Carla
The price is ¥10,863
¥12,465 total
includes taxes & fees
Dec 16 - Dec 17
Reelfoot Lake Inn

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (726)
This welcoming motel offers clean rooms praised by guests, plus convenient amenities including free WiFi and parking. The 24-hour front desk ensures assistance anytime during your stay in charming Portageville.

"Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling."
United States
Roger
New Orleans Inn Portageville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular New Madrid attractions

Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic story of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

Mississippi River Walk at New Madrid.  A magnificent view of the Mississippi river from atop of the levee.  A steamboat is docked down river. .

Top New Madrid Hotel Reviews

More cheap stays in New Madrid

Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 19 mi (30.5 km) from the heart of New Madrid, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Fairfield Inn & Suites by Marriott Sikeston and For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.. See all available top hotels, or vacation rentals in New Madrid.
What are some of the best vacation home rentals that New Madrid has to offer?
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!: This New Madrid vacation home rental offers a garden, a selection of games, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
Where can I learn more about changing or cancelling my trip to New Madrid?
For additional details about updating your trip to New Madrid or cancelling it, head over to our customer service page.
What's the best hotel to stay with easy access to New Madrid Historical Museum?
Travel Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. You'll find it 6.8 mi (10.9 km) from New Madrid Historical Museum. Other good options around the area include Reelfoot Lake Inn and Lodge that sleeps 16! Ideal for Fishermen, Family reunions, Hunters and Tourist!.
What about the best place to stay near Hunter-Dawson State Historic Site?
One of the top choices for your stay is Travel Inn, located 7.2 mi (11.6 km) from Hunter-Dawson State Historic Site, and this hotel offers free breakfast and free parking. Reelfoot Lake Inn and Lodge that sleeps 16! Ideal for Fishermen, Family reunions, Hunters and Tourist! are other good choices within the area.
What's the best accommodation near Cairo Regional Airport (CIR)?
Quality Inn Cairo I-57 is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.1 mi (3.3 km) from Cairo Regional Airport.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer including the parks and museums. There are 53 hotels and other accommodations in the surrounding area. Find out more about New Madrid.
What are the top places to visit in New Madrid?
Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your agenda are River Ridge Winery and Mississippi River. Check out what more to see and do in Expedia's New Madrid guide.
What's the weather like in New Madrid?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 42°F. Average annual precipitation for New Madrid is 60 inches.