Find hotels in Lilbourn, MO from ¥7,688

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Our top choices for Lilbourn hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
Located just off the highway near Sikeston dining and shopping, this hotel offers both indoor and outdoor pools for year-round swimming. Guests praise the peaceful atmosphere, helpful staff, and complimentary breakfast, parking, and WiFi.

"This our favorite place to stop for a good night sleep. "
United States
Eileen
The price is ¥14,090
¥16,199 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Drury Inn & Suites Sikeston, MO

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1002)
Located in Sikeston, this hotel offers an indoor pool for relaxing swims after a day of exploring. Near Central Park and the Sikeston Depot Museum, guests praise the delicious free breakfast and attentive service.

"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ¥11,835
¥13,488 total
includes taxes & fees
Dec 29 - Dec 30
Best Western Plus Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (724)
Enjoy tranquil accommodations at this welcoming Sikeston hotel where helpful staff receive consistent praise. Located near Central Park and Sikeston Depot Museum, guests appreciate the quiet atmosphere, clean rooms, and daily continental breakfast.

"Room was good as usual. This is 4th stay over past 5 years. Only issue I had on this stay was the orange juice from breakfast options. "
United States
Todd
The price is ¥8,688
¥9,904 total
includes taxes & fees
Dec 29 - Dec 30
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (43)
This business-friendly hotel offers an indoor pool, restaurant, and complimentary breakfast. Located near Sikeston Depot Museum, guests enjoy free WiFi and parking while exploring local attractions.

"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is ¥15,814
¥17,906 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Fairfield Inn & Suites by Marriott Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (453)
Take a refreshing dip in the indoor pool or maintain your routine at the fitness center. Free breakfast, WiFi, and parking enhance your stay. Central Park and Sikeston Depot Museum are just moments away from this welcoming retreat.

"clean room, comfy bedding, nice staff, convenient location "
United States
Alexa
The price is ¥15,278
¥17,299 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (444)
Discover comfort at this Sikeston hotel with an indoor pool and fitness center. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby Central Park and Sikeston Depot Museum. Guests consistently praise the helpful staff and immaculate rooms.

"Stay was excellent "
United States
Kourtney
The price is ¥14,561
¥16,487 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express & Suites Sikeston Southwest by IHG

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (732)
This welcoming motel offers clean rooms praised by guests, plus convenient amenities including free WiFi and parking. The 24-hour front desk ensures assistance anytime during your stay in charming Portageville.

"Friendly sta"
United States
Melissa
New Orleans Inn Portageville

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1005)
Escape to this serene retreat with both indoor and outdoor pools for year-round enjoyment. The fitness center keeps your routine intact while complimentary breakfast energizes your day exploring nearby Central Park and Sikeston Depot Museum.

"Everything was clean, staff was friendly "
United States
Matthew
The price is ¥11,741
¥13,498 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Pear Tree Inn Sikeston

Quality Inn Hayti North

Quality Inn Hayti North
2.5 star property
Hayti
6.8 out of 10, (469)
Relax at this friendly hotel with a seasonal outdoor pool just minutes from Hayti Park and Black Island Conservation Area. Guests praise the helpful staff while enjoying free breakfast, WiFi, and parking.

"Staff was good "
United States
Gabriel
The price is ¥9,159
¥10,439 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn Hayti North

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (282)
Experience refreshing comfort at this Sikeston hotel with an indoor swimming pool and fitness center. Near Central Park and Sikeston Depot Museum, travelers appreciate the helpful staff, complimentary WiFi, and free parking for a convenient, stress-free stay.

"Room was clean, breakfast was very good. "
United States
Connie
The price is ¥13,841
¥15,775 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Comfort Inn & Suites Sikeston I-55

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
3.0 star property
Hayti
9.4 out of 10, Exceptional, (1000)
Located just minutes from Mississippi River, this relaxing retreat offers complimentary breakfast, WiFi, and parking. The indoor pool provides year-round enjoyment while the hot tub ensures perfect unwinding. Near Hayti Park and praised for its peaceful atmosphere and attentive staff.

"Staff is very friendly. Breakfast was good. "
United States
Samantha
The price is ¥14,716
¥16,772 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Drury Inn & Suites Hayti Caruthersville

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (390)
Just minutes from The Heritage House and Keller Veteran Memorial, this practical hotel offers American cuisine at Penny's Diner, serving three meals daily. Business travelers appreciate the free WiFi, parking, and 24-hour assistance.

"Clean room, friendly staff and quiet stay."
United States
Margo
The price is ¥12,095
¥13,580 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Travelodge by Wyndham Dexter

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
7.8 out of 10, Good, (39)
This hotel in Marston offers complimentary perks including daily full breakfast served between 6:00 AM and 9:00 AM, WiFi, and self parking. Conveniently located for travelers exploring the area.

"Great hotel, great staff"
United States
Dmitry
The price is ¥9,026
¥10,309 total
includes taxes & fees
Dec 30 - Dec 31
Super 8 By Wyndham Marston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1004)
This tranquil Sikeston hotel offers complimentary on-the-go breakfast and WiFi, plus convenient access to Central Park and Sikeston Depot Museum. Guests appreciate the helpful staff, clean rooms, and free parking, with a fitness center for morning workouts.

"Everything was excellent. Verify happy with everything. Stayed 3 weeks for work and already booked 2 more stays."
United States
James
The price is ¥9,848
¥11,225 total
includes taxes & fees
Dec 30 - Dec 31
Days Inn and Suites by Wyndham Sikeston

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (569)
Start your day with complimentary breakfast at this Sikeston hotel. Enjoy free WiFi and parking while staying minutes from Central Park and the Sikeston Depot Museum. Cape Girardeau Municipal Airport is just a 29-minute drive away.

"Excellent check-in process! Extremely friendly staff. Room is very adequate. Everything you need. Price was a great bargain."
United States
Ronald
The price is ¥9,300
¥10,601 total
includes taxes & fees
Dec 29 - Dec 30
Super 8 by Wyndham Sikeston/Miner Area

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (461)
"Bed bugs in two separate rooms, wouldn’t refund my room"
United States
Jacquelynn
The price is ¥10,916
¥12,527 total
includes taxes & fees
Dec 29 - Dec 30
Reelfoot Lake Inn

Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (333)
This welcoming inn features a refreshing seasonal outdoor pool for summer relaxation. Located near The Heritage House and Keller Veteran Memorial, guests consistently praise the attentive staff. Enjoy convenient amenities and free self parking during your visit.

"Room was nice and spacious."
United States
Rebecca
The price is ¥10,177
¥11,428 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Dexter Inn

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (9)
Set near Central Park and Sikeston Depot Museum, this business-friendly hotel offers a refreshing indoor pool and convenient daily breakfast. Enjoy well-appointed accommodations with complimentary WiFi and self parking just 32 minutes from Cairo Regional Airport.

"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is ¥18,475
¥20,918 total
includes taxes & fees
Jan 4 - Jan 5, 2026
TownePlace Suites by Marriott Sikeston

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (121)
This Sikeston motel offers a convenient base for exploring nearby Central Park and Sikeston Depot Museum. Enjoy thoughtful amenities like free WiFi and parking alongside 24-hour front desk service for assistance anytime.

"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is ¥8,367
¥9,953 total
includes taxes & fees
Dec 29 - Dec 30
Country Yard Inn and Suite

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (5)
"Great stay "
United States
Ashley
The price is ¥16,562
¥18,597 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hampton Inn By Hilton Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lilbourn Hotel Reviews

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Frequently asked questions

Where is the best place to stay in Lilbourn?
Located 21.2 mi (34.2 km) from the heart of Lilbourn, Drury Inn & Suites Sikeston, MO is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Hampton Inn Sikeston and Drury Inn & Suites Hayti Caruthersville. See all available top hotels, or vacation rentals in Lilbourn.
What are some of the best vacation rentals in Lilbourn?
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters: This vacation home rental near Lilbourn is located on a lake and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Lilbourn.
If I need to cancel my hotel reservation in Lilbourn, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Lilbourn.
Where can I learn more about changing or cancelling my trip to Lilbourn?
To access more information about rescheduling or cancelling your trip to Lilbourn, head over to our customer service page.
What is staying in Lilbourn like?
Travelers to Lilbourn will find plenty to explore and enjoy. There are 68 hotels and other accommodations in the surrounding area. Find out more about Lilbourn.
What is there to see in Lilbourn?
Places to visit in the wider area include New Madrid Historical Museum, Marston Community Center, and Reelfoot Lake. You'll also find Sikeston Depot Museum and River Ridge Winery in the area. Check out what more to see and do in Expedia's Lilbourn guide.
What's the weather like in Lilbourn?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 42°F. Average annual precipitation for Lilbourn is 60 inches.