Cape Girardeau, MO

Travel Guide

Photo by Skyy
Photo by Skyy
Photo by Jessica King
Photo by Jessica King
Photo by Skyy
Photo by Skyy
Photo by Alice Burghart
Photo by Alice Burghart
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
The price is ￥13,264 per night from Sep 1 to Sep 2
￥13,264
￥14,962 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,004 reviews)
"Excellent Check in was amazing. Lady at the counter was very patient and very helpful"

Reviewed on Aug 18, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
The price is ￥15,619 per night from Aug 24 to Aug 25
￥15,619
￥17,620 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.2/10 Wonderful! (393 reviews)
"Great"

Reviewed on Aug 21, 2025

The Riverview
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
The price is ￥10,316 per night from Sep 1 to Sep 2
￥10,316
￥11,638 total
Sep 1 - Sep 2
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
"Ok hotel. Good for a single night stop over. Next to outback."

Reviewed on Aug 17, 2025

Pear Tree Inn Cape Girardeau West
See all 151 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse

Cape Girardeau
Stay at this cabin in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions Cape Girardeau Conservation Nature Center and Cape ...
10/10 Exceptional! (20 reviews)
"The place was awesome very clean the host was very accommodating. Nice a quiet for a relaxing stay highly recommend"

Reviewed on Aug 18, 2025

The Twisted Sassafras Treehouse
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a garden, and in-room jetted tubs. Popular attractions eDen Spa & Salon and Riverfront Park are located ...
9.6/10 Exceptional! (38 reviews)
"Very clean and had everything we needed! Walking distance to campus and downtown. Definitely would recommend"

Reviewed on Jul 23, 2025

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and eDen Spa & Salon are ...
9.8/10 Exceptional! (168 reviews)
"Property location was perfect.Deck view was great.Very clean and comfortable place."

Reviewed on Jul 21, 2025

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
See all properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Southeast Missouri State University

Isle Casino Cape Girardeau

Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

Isle Casino Cape Girardeau

Riverfront Bridge Park

Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Bridge Park

Show Me Center

Catch an event at Show Me Center during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Show Me Center

Saint Francis Medical Center

Though Saint Francis Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Cape Girardeau while you are here.

Saint Francis Medical Center

Riverfront Park

Riverfront Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Park