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Cape Girardeau Vacation Rentals

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Vacation Rentals in Cape Girardeau

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Cape Girardeau
9.6 out of 10, Exceptional, (42)
"The process was flawless and the location is close to everything!! We enjoyed our stay!"
United States
Jack W.
The price is ¥12,618
¥21,313 total
includes taxes & fees
Nov 17 - Nov 18
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

The Cottage, Rusted Route Farms

Jackson
10.0 out of 10, Exceptional, (2)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is ¥19,258
¥30,504 total
includes taxes & fees
Nov 13 - Nov 14
The Cottage, Rusted Route Farms

Little Blue Cottage on Spanish

Cape Girardeau
8.6 out of 10, Excellent, (46)
"We stayed here to visit our two children going to SEMO. Everything about the place was perfect for a couple. The place was cute and the location was perfect"
United States
Beth G.
The price is ¥12,479
¥15,560 total
includes taxes & fees
Nov 13 - Nov 14
Little Blue Cottage on Spanish

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Cape Girardeau
8.8 out of 10, Excellent, (34)
"Loved this location for our FFA Officer Retreat! Lots of things to do for high school aged students and space to getting planning done for the school year. Loved the outdoor fire pit and pool. "
United States
Ann P.
The price is ¥20,798
¥33,394 total
includes taxes & fees
Nov 18 - Nov 19
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau
10.0 out of 10, Exceptional, (146)
"Three generations found rest,beauty,& joy at Serenity South. Thoughtful touches,beautiful gardens and Cape charm made this more than a stay-it became a treasured memory. We were so appreciative of the details, the fresh flowers, homemade cookies, the coffeemaker upstairs and the books and games. The beds were all comfortable. We enjoyed this historical home and our stay. "
United States
Linden S.
The price is ¥23,109
¥37,737 total
includes taxes & fees
Nov 13 - Nov 14
Serenity South -- Gardens, River-Views, and Refreshing Space

Gorgeous 1856 Log Cabin, Completely Renovated

Jackson
10.0 out of 10, Exceptional, (3)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is ¥30,812
¥47,759 total
includes taxes & fees
Nov 13 - Nov 14
Gorgeous 1856 Log Cabin, Completely Renovated

The Twisted Sassafras Treehouse

Cape Girardeau
10.0 out of 10, Exceptional, (26)
"We were celebrating 28th Anniversary and this property was perfect."
United States
Tim G.
The price is ¥35,280
¥50,646 total
includes taxes & fees
Dec 8 - Dec 9
The Twisted Sassafras Treehouse

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Cape Girardeau
9.6 out of 10, Exceptional, (7)
"Nice place, great times"
United States
Jace W.
The price is ¥41,458
¥67,412 total
includes taxes & fees
Nov 18 - Nov 19
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna
10.0 out of 10, Exceptional, (402)
"Serene, well appointed cabin, front porch rocker back deck"
United States
Christine
The price is ¥18,025
¥31,186 total
includes taxes & fees
Nov 16 - Nov 17
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Charming cottage overlooking Lake Acre

Dongola
10.0 out of 10, Exceptional, (100)
"Grate place beautiful peaceful and quiet love the little nesting birds on the front porch can’t wait to come back "
United States
Paul D.
The price is ¥23,109
¥46,042 total
includes taxes & fees
Dec 1 - Dec 2
Charming cottage overlooking Lake Acre

Charming 2-bedroom apartment in fabulous Marble Hill with AC

Marble Hill
7.0 out of 10, Good, (4)
"Clean and comfortable. There was a minor hiccup with the refrigerator, but that was promptly resolved by Diana. Overall, a very nice place for the price. "
United States
Martin A.
The price is ¥13,095
¥21,957 total
includes taxes & fees
Dec 11 - Dec 12
Charming 2-bedroom apartment in fabulous Marble Hill with AC

Cozy cabins on beautiful Horseshoe Lake

Olive Branch
9.8 out of 10, Exceptional, (34)
"Great little cabin and very clean. I enjoyed my stay! It wasn’t on the lake as I pictured but other than that it was perfect."
United States
Lori B.
The price is ¥17,332
¥21,635 total
includes taxes & fees
Nov 13 - Nov 14
Cozy cabins on beautiful Horseshoe Lake

Beautiful location in the secluded woods

Pomona
10.0 out of 10, Exceptional, (56)
"Easy access and beautiful location "
United States
Wilmer W.
The price is ¥15,252
¥27,757 total
includes taxes & fees
Nov 30 - Dec 1
Beautiful location in the secluded woods

Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Jonesboro
10.0 out of 10, Exceptional, (2)
"great place. wonderful host."
United States
Carla m.
The price is ¥18,487
¥41,145 total
includes taxes & fees
Nov 13 - Nov 14
Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Villa B offers peace and quiet with beautiful views of the countryside.

Jackson
10.0 out of 10, Exceptional, (11)
"Our stay was amazing. Everything was so clean organized, and anything you would possibly need was in the room. We will definitely be staying there again when in the area!!"
United States
Karen P.
The price is ¥23,109
¥28,463 total
includes taxes & fees
Nov 18 - Nov 19
Villa B offers peace and quiet with beautiful views of the countryside.

The Rested Duck Mallard Room

Olive Branch
9.2 out of 10, Wonderful, (25)
"We were in the area for a few days turkey hunting and this place was just awesome. Thanks again!"
United States
Chris L.
The price is ¥17,332
¥21,635 total
includes taxes & fees
Nov 16 - Nov 17
The Rested Duck Mallard Room

Contemporary Glamping with Native American Appeal

Anna
9.8 out of 10, Exceptional, (155)
"Great stay! Perfect for our family and dog while we visited friends in Cobden. Cute and well appointed cabin!"
United States
Kristin N.
The price is ¥31,274
¥53,047 total
includes taxes & fees
Nov 22 - Nov 23
Contemporary Glamping with Native American Appeal

Peaceful secluded cabin located near Horseshoe Lake

Miller City
9.8 out of 10, Exceptional, (20)
"Loved the cabin! Bed was super comfy! We really enjoyed the porch! We will definitely be back!!"
United States
Fawn S.
The price is ¥21,568
¥33,632 total
includes taxes & fees
Nov 23 - Nov 24
Peaceful secluded cabin located near Horseshoe Lake

Relax in the country at Countryside Villas! - Villa A

Jackson
10.0 out of 10, Exceptional, (33)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is ¥23,109
¥28,463 total
includes taxes & fees
Nov 13 - Nov 14
Relax in the country at Countryside Villas! - Villa A
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Find out more about Cape Girardeau

Search for holiday rentals in Cape Girardeau on Expedia! You can easily find your home rentals, villas, holiday apartments in Cape Girardeau using one of the methods below:

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Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

Little Blue Cottage on Spanish: This Cape Girardeau vacation home rental comes with WiFi so you can feel at home during your trip. Some other homes for rent in Cape Girardeau include Quaint, Beautiful Home next to SEMO and Hospital and Serenity South -- Gardens, River-Views, and Refreshing Space.

How many vacation rentals will I find in Cape Girardeau?

Choose from 22 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, Isle Casino Cape Girardeau and Show Me Center are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.