Photo by Alice Burghart

Find hotels in Cape Girardeau, MO from ￥10,415

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Compare 170 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, (1001)
"Great place"
United States
Eric
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1004)
"Everything was clean and looked newly renovated. Staff was friendly. Parking was convenient and the area seemed safe. "
United States
Lisa
Pear Tree Inn Cape Girardeau West
Lobby sitting area
The Riverview
The Riverview
4.0 star property
9.4 out of 10, Exceptional, (443)
"Location was perfect for family weekend!"
United States
Kelly
The Riverview
Business center
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (1003)
"The staff was beyond friendly, the free breakfast did not disappointed, and we were just genuinely happy with our stay."
United States
Merleen
Drury Inn & Suites Cape Girardeau
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1004)
"Always enjoy our stay. Staff is very friendly, especially at breakfast! "
United States
Paul
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
9.4 out of 10, Exceptional, (1001)
"Clean and welcoming. Tyler at the front desk for check in was engaging and friendly. He’s a gem!!"
United States
Penny
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 star property
8.0 out of 10, Very Good, (862)
"Great staff and convenient location "
United States
Greg
Candlewood Suites Cape Girardeau by IHG
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 star property
9.6 out of 10, Exceptional, (83)
"The staff was very kind and welcoming!"
United States
Natalie
Tru By Hilton Cape Girardeau
Lobby
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
9.6 out of 10, Exceptional, (457)
"Very clean and upscale hotel."
United States
Mike
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Quality Inn
Quality Inn
2.5 star property
7.2 out of 10, Good, (661)
"nice stay"
United States
Brandon
Quality Inn
Courtyard
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 star property
9.6 out of 10, Exceptional, (763)
"Seemed newly updated, very friendly staff"
United States
Harry
Hampton Inn Cape Girardeau I 55 East
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
9.4 out of 10, Exceptional, (132)
"Excellent hotel…"
United States
Danny
Fairfield Inn & Suites by Marriott Cape Girardeau
Desk, free WiFi
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 star property
6.0 out of 10, (201)
"I was okay for one quick night in a very convenient location for me."
United States
Andreas
Town House Inn Cape Giradreau
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn
Rockwood Inn
2.0 star property
10.0 out of 10, Exceptional, (16)
"Very beautiful property and we loved the old school feel and hospitality"
United States
Matthew
Rockwood Inn
Lobby
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, (1009)
"Great service! Definitely will stay there again!"
United States
David
Drury Inn & Suites Jackson MO
Free daily on-the-go breakfast
Hotel 7 Inn Anna
Hotel 7 Inn Anna
2.5 star property
6.6 out of 10, (214)
"V"
United States
Teanna
Hotel 7 Inn Anna
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
8.8 out of 10, Excellent, (644)
"Stayed on our way south for vacation. It was a clean nice place to stay. "
United States
Joel
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Deluxe Double Room | Premium bedding, individually decorated, individually furnished
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
3.0 star property
9.6 out of 10, Exceptional, (80)
"Quiet small town vibe, great food and service! Definitely recommend "
United States
Donald
EC Reed's Mercantile and Hotel
Lobby
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 star property
8.2 out of 10, Very Good, (737)
"Great area, fast check in, quiet, very spacious"
United States
Jeanne
Comfort Suites Jackson-Cape Girardeau
Front of property - evening/night
Makanda Inn
Makanda Inn
3.5 star property
10.0 out of 10, Exceptional, (33)
"Big thank you to the team at the cabin! Great people, great service, and great food! "
United States
Charles
Makanda Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Cape Girardeau attractions

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
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Isle Casino Cape Girardeau

4.2/5 (104 reviews)
Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.
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Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau
Beautiful city by the Mississippi River
Photo by Alice Burghart
Open Photo by Alice Burghart

Top Cape Girardeau Hotel Reviews

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

10/10 Excellent
"Amazing hotel all around"
Brian 1-night trip
Posted 2 days ago
Tru By Hilton Cape Girardeau

More cheap stays in Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau, MO
The price is ￥10,778 per night from Nov 6 to Nov 7
￥10,778
￥12,159 total
Nov 6 - Nov 7
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)

Frequently asked questions

What's the best place to stay in Cape Girardeau?
Fairfield Inn & Suites by Marriott Cape Girardeau is a favorite property for Expedia customers. This hotel offers free breakfast and an indoor pool. Other favorite options based on traveler reviews include Courtyard by Marriott Cape Girardeau Downtown and Drury Plaza Hotel Cape Girardeau Conference Center. See all available top hotels, or vacation rentals in Cape Girardeau.
What are some of the best vacation home rentals in Cape Girardeau?
Serenity South -- Gardens, River-Views, and Refreshing Space: This highly rated vacation home rental in Cape Girardeau is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Other favorite homes for rent in Cape Girardeau are Little Blue Cottage on Spanish and "Brickyard"-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau. See all vacation rentals in Cape Girardeau.
If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?
Yes, the majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.
Where can I learn more about changing or cancelling my trip to Cape Girardeau?
For more details about picking new dates or cancelling your trip to Cape Girardeau, head over to our customer service page.
What's the best budget-friendly accommodation in Cape Girardeau?
Based on reviews, Pear Tree Inn Cape Girardeau West is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Another top option for your stay on the cheap is Pear Tree Inn Cape Girardeau Near the Medical Center. View all budget hotels in Cape Girardeau.
What's the best hotel for families in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Other good choices to stay with the kids include Pear Tree Inn Cape Girardeau West and Pear Tree Inn Cape Girardeau Near the Medical Center. Attractions like Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also fun for kids of all ages. Find more child-friendly accommodations in Cape Girardeau.
What is the top LGBTQ-friendly place to stay in Cape Girardeau?
Pear Tree Inn Cape Girardeau Near the Medical Center is a top LGBTQ-friendly hotel, and features free WiFi and LCD TVs. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are two other good options for your trip. See all available hotels listed as LGBTQ-friendly in Cape Girardeau.
What's the best pet-friendly hotel in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a top hotel for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Other good choices to stay with your pet include Tru By Hilton Cape Girardeau and Pear Tree Inn Cape Girardeau West. See more pet-friendly hotel accommodations in Cape Girardeau.
Where is the best hotel to stay with easy access to Southeast Missouri State University?
Courtyard by Marriott Cape Girardeau Downtown is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers a restaurant and free parking. It's located just a short 0.8 mi (1.3 km) from Southeast Missouri State University. Other good choices within a few miles include Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West.
What about the best place to stay close to Show Me Center?
One of the top choices for your stay is Courtyard by Marriott Cape Girardeau Downtown, located a short 1 mi (1.6 km) from Show Me Center, and this 3-star hotel offers a restaurant and free parking. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are two other good options within a few miles.
What are some accommodations with pools in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top hotel with a pool, a full-service spa, and free WiFi. View all hotels with pools in Cape Girardeau.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness center. See all spa hotels in Cape Girardeau.
What's the best place to stay near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What is staying in Cape Girardeau like?
History buffs will enjoy exploring Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting, and shopping. In Cape Girardeau, there are 57 hotels and other accommodations to choose from. Find out more about Cape Girardeau.
What are the top places to visit in Cape Girardeau?
Families come for attractions such as Cape Splash Family Aquatic Center, Cape Girardeau Conservation Nature Center, and Lazy L Safari Park. Landmarks like The Glenn House and Fort D Historic Site might be worth a visit. Natural beauty is on display at Shawnee National Forest, Mississippi River, and Cape Rock Park. Check out what more to see and do in Expedia's Cape Girardeau guide.
What's the weather like in Cape Girardeau?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.

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