Photo by Alice Burghart

Find hotels in Cape Girardeau, MO from ¥10,329

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 170 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, (1005)
"Very nice stay."
United States
Charity
The price is ¥13,756
¥15,517 total
includes taxes & fees
Nov 2 - Nov 3
Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview
4.0 star property
9.4 out of 10, Exceptional, (441)
"Location was perfect for family weekend!"
United States
Kelly
The price is ¥16,598
¥18,726 total
includes taxes & fees
Oct 28 - Oct 29
The Riverview
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1003)
"Great stay"
United States
Heather
The price is ¥10,699
¥12,070 total
includes taxes & fees
Oct 28 - Oct 29
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (1002)
"Everything nice clean and friendly"
United States
Megan
The price is ¥13,756
¥15,517 total
includes taxes & fees
Oct 31 - Nov 1
Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1004)
"Always enjoy our stay. Staff is very friendly, especially at breakfast! "
United States
Paul
The price is ¥10,699
¥12,070 total
includes taxes & fees
Oct 28 - Oct 29
Pear Tree Inn Cape Girardeau Near the Medical Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
9.4 out of 10, Exceptional, (1001)
"It was right off the interstate with lots of restaurant options "
United States
Kelly
The price is ¥14,522
¥16,383 total
includes taxes & fees
Nov 2 - Nov 3
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 star property
8.2 out of 10, Very Good, (860)
"Great staff and convenient location "
United States
Greg
The price is ¥11,617
¥13,947 total
includes taxes & fees
Nov 14 - Nov 15
Candlewood Suites Cape Girardeau by IHG
Tru By Hilton Cape Girardeau
2.5 star property
9.6 out of 10, Exceptional, (81)
"The staff was very kind and welcoming!"
United States
Natalie
The price is ¥13,663
¥15,550 total
includes taxes & fees
Nov 2 - Nov 3
Tru By Hilton Cape Girardeau
Quality Inn
2.5 star property
7.2 out of 10, Good, (661)
"Great place with great employees"
United States
Jessica
The price is ¥9,156
¥10,329 total
includes taxes & fees
Nov 6 - Nov 7
Quality Inn
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
9.6 out of 10, Exceptional, (457)
"The Staff was friendly The restaurant was good"
United States
Sirron
The price is ¥17,732
¥20,092 total
includes taxes & fees
Nov 23 - Nov 24
Courtyard by Marriott Cape Girardeau Downtown
Hampton Inn Cape Girardeau I 55 East
2.5 star property
9.6 out of 10, Exceptional, (762)
"The property staff were lovely and the hotel was clean and renovated!"
United States
Mary
The price is ¥16,170
¥18,241 total
includes taxes & fees
Nov 2 - Nov 3
Hampton Inn Cape Girardeau I 55 East
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
9.4 out of 10, Exceptional, (131)
"Excellent hotel…"
United States
Danny
The price is ¥14,163
¥15,978 total
includes taxes & fees
Nov 9 - Nov 10
Fairfield Inn & Suites by Marriott Cape Girardeau
Town House Inn Cape Giradreau
2.5 star property
6.0 out of 10, (200)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is ¥9,936
¥11,607 total
includes taxes & fees
Oct 28 - Oct 29
Town House Inn Cape Giradreau
Rockwood Inn
2.0 star property
10.0 out of 10, Exceptional, (16)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is ¥21,135
¥23,843 total
includes taxes & fees
Nov 27 - Nov 28
Rockwood Inn
Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, (1004)
"This was a wonderful stay. We will definitely stay again when we are in town!"
United States
Trista
The price is ¥13,756
¥14,543 total
includes taxes & fees
Oct 31 - Nov 1
Drury Inn & Suites Jackson MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
8.8 out of 10, Excellent, (641)
"We had a restful stay very safe & clean! Friendly staff:)"
United States
Rachel
The price is ¥12,863
¥13,921 total
includes taxes & fees
Oct 29 - Oct 30
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Hotel 7 Inn Anna
2.5 star property
6.6 out of 10, (213)
"The staff was wonderful"
United States
Donna
The price is ¥13,757
¥15,267 total
includes taxes & fees
Oct 28 - Oct 29
Hotel 7 Inn Anna
Town House Inn
2.5 star property
7.6 out of 10, Good, (419)
"Room was clean and had a refrigerator and microwave for use if needed."
United States
Sherry
The price is ¥10,347
¥11,198 total
includes taxes & fees
Nov 24 - Nov 25
Town House Inn
EC Reed's Mercantile and Hotel
3.0 star property
9.6 out of 10, Exceptional, (80)
"Quiet small town vibe, great food and service! Definitely recommend "
United States
Donald
EC Reed's Mercantile and Hotel
Comfort Suites Jackson-Cape Girardeau
2.5 star property
8.2 out of 10, Very Good, (737)
"Great area, fast check in, quiet, very spacious"
United States
Jeanne
The price is ¥13,605
¥14,723 total
includes taxes & fees
Oct 28 - Oct 29
Comfort Suites Jackson-Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Cape Girardeau attractions

Learn more about Cape Girardeau

Trip time! Discover the riverfront, history, and local cuisine in Cape Girardeau.

The Bar - this was one location Gone Girl was filmed at!
Photo by Skyy
Open Photo by Skyy

Top Cape Girardeau Hotel Reviews

More cheap stays in Cape Girardeau

Frequently asked questions

What's the best place to stay in Cape Girardeau?
Fairfield Inn & Suites by Marriott Cape Girardeau is a favorite property for Expedia customers. This hotel offers free breakfast and an indoor pool. Other favorite options based on traveler reviews include Courtyard by Marriott Cape Girardeau Downtown and Drury Plaza Hotel Cape Girardeau Conference Center. See all available top hotels, or vacation rentals in Cape Girardeau.
What are some of the best vacation home rentals in Cape Girardeau?
Serenity South -- Gardens, River-Views, and Refreshing Space: This highly rated vacation home rental in Cape Girardeau is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Other favorite homes for rent in Cape Girardeau are Little Blue Cottage on Spanish and "Brickyard"-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau. See all vacation rentals in Cape Girardeau.
If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?
Yes, the majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.
Where can I learn more about changing or cancelling my trip to Cape Girardeau?
For more details about picking new dates or cancelling your trip to Cape Girardeau, head over to our customer service page.
What's the best budget-friendly accommodation in Cape Girardeau?
Based on reviews, Pear Tree Inn Cape Girardeau West is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Another top option for your stay on the cheap is Pear Tree Inn Cape Girardeau Near the Medical Center. View all budget hotels in Cape Girardeau.
What's the best hotel for families in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Other good choices to stay with the kids include Pear Tree Inn Cape Girardeau West and Pear Tree Inn Cape Girardeau Near the Medical Center. Attractions like Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also fun for kids of all ages. Find more child-friendly accommodations in Cape Girardeau.
What is the top LGBTQ-friendly place to stay in Cape Girardeau?
Pear Tree Inn Cape Girardeau Near the Medical Center is a top LGBTQ-friendly hotel, and features free WiFi and LCD TVs. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are two other good options for your trip. See all available hotels listed as LGBTQ-friendly in Cape Girardeau.
What's the best pet-friendly hotel in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a top hotel for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Other good choices to stay with your pet include Tru By Hilton Cape Girardeau and Pear Tree Inn Cape Girardeau West. See more pet-friendly hotel accommodations in Cape Girardeau.
Where is the best hotel to stay with easy access to Southeast Missouri State University?
Courtyard by Marriott Cape Girardeau Downtown is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers a restaurant and free parking. It's located just a short 0.8 mi (1.3 km) from Southeast Missouri State University. Other good choices within a few miles include Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West.
What about the best place to stay close to Show Me Center?
One of the top choices for your stay is Courtyard by Marriott Cape Girardeau Downtown, located a short 1 mi (1.6 km) from Show Me Center, and this 3-star hotel offers a restaurant and free parking. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are two other good options within a few miles.
What are some accommodations with pools in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top hotel with a pool, a full-service spa, and free WiFi. View all hotels with pools in Cape Girardeau.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness center. See all spa hotels in Cape Girardeau.
What's the best place to stay near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What is staying in Cape Girardeau like?
History buffs will enjoy exploring Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting, and shopping. In Cape Girardeau, there are 57 hotels and other accommodations to choose from. Find out more about Cape Girardeau.
What are the top places to visit in Cape Girardeau?
Families come for attractions such as Cape Splash Family Aquatic Center, Cape Girardeau Conservation Nature Center, and Lazy L Safari Park. Landmarks like The Glenn House and Fort D Historic Site might be worth a visit. Natural beauty is on display at Shawnee National Forest, Mississippi River, and Cape Rock Park. Check out what more to see and do in Expedia's Cape Girardeau guide.
What's the weather like in Cape Girardeau?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.

Explore a world of travel with Expedia