Apartments in Cape Girardeau County for Rent

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Top cities in Cape Girardeau County

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Cape Girardeau

Cape Girardeau

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Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3

Our top choices for Cape Girardeau County apartments

A modern living room with a sectional sofa, a coffee table, a TV mounted on the wall, and a window with blinds.

1. The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.
Murphysboro
9.6 out of 10, Exceptional, (35 reviews)
"We enjoyed our visit"
United States
Tim P.
The price is ￥19,257
￥29,984 total
includes taxes & fees
Nov 7 - Nov 8
The Lab! Come stay in our brand new space.
A large outdoor area with a pond, several wooden cabins, and a road.

2. Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois
Murphysboro
9.0 out of 10, Wonderful, (8 reviews)
"Easy check in and was very clean and close to everything. "
United States
Stephen
The price is ￥13,947
￥36,115 total
includes taxes & fees
Nov 8 - Nov 9
Pet Friendly! Couples Retreat in Southern Illinois
A bedroom with a bed, a bedside table, a chair, a small table, and a window with blinds.

3. Vulture's Roost

Vulture's Roost
Makanda
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful place! Everything you need! Love the eclectic decor. Hostesses were easy to communicate with. Very close to Giant City State Park for hiking etc. also antiquing in nearby towns."
United States
cris g.
The price is ￥18,916
￥31,738 total
includes taxes & fees
Nov 8 - Nov 9
Vulture's Roost
A kitchen with wooden cabinets, a granite countertop, a black refrigerator, and a window with dark curtains.

4. Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau
10.0 out of 10, Exceptional, (229 reviews)
"Very nice hospitality and accommodations ComfortableGreat location"
United States
Cecilia W.
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
A kitchen with wooden cabinets, a black refrigerator, a microwave, a stove, and a ceiling fan. There are three stools at the island.

5. Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (39 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is ￥23,753
￥27,172 total
includes taxes & fees
Nov 15 - Nov 16
Relax in the country at Countryside Villas! - Villa A
A spacious living room with a dark brown leather sofa, a wooden coffee table, and a piano.

6. Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
Cape Girardeau
9.0 out of 10, Wonderful, (30 reviews)
"The place awesome easy to find and it was very clean the whole group was very happy with it would stay again!!!"
United States
John W.
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
A modern kitchen with white cabinets, a stainless steel sink, and a wooden countertop.

7. 2Bdrm Stay in Downtown Cape, Walkable, Laundry

2Bdrm Stay in Downtown Cape, Walkable, Laundry
Cape Girardeau
10.0 out of 10, Exceptional, (6 reviews)
"Super nice place right next to the river / downtown. Perfect for small families or young married couples. Would definitely book again! "
United States
Dustin W.
2Bdrm Stay in Downtown Cape, Walkable, Laundry
A modern kitchen with a central island, a built-in washer and dryer, and a dining area with a sofa and chairs.

8. Downtown Urban Loft #4

Downtown Urban Loft #4
Perryville
Downtown Urban Loft #4
A wooden deck with a ramp leading to a covered area, a small window, and a metal chair.

9. Murphysboro Retreat w/ Deck Near Kinkaid Lake!

Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Murphysboro
10.0 out of 10, Exceptional, (37 reviews)
"Very clean and comfortable stay. The host has thought of everything— including lots of nice touches that set the property apart. I will definitely stay again when in the Murphysboro area!"
United States
Margaret Q.
Murphysboro Retreat w/ Deck Near Kinkaid Lake!
A modern kitchen with stainless steel appliances, a large window, and a breakfast setup on the counter.

10. Gorgeous, downtown house!

Gorgeous, downtown house!
Perryville
10.0 out of 10, Exceptional, (1 review)
"Our stay was excellent and our host Carisa was a Great person to work with. The house was beautiful. The house worked out great for us. We had 6 people staying and we all had very comfortable beds and our own bathrooms. Great for a large family. "
United States
Doyle or Cheryl D.
The price is ￥80,830
￥132,701 total
includes taxes & fees
Nov 9 - Nov 10
Gorgeous, downtown house!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top reviews in Cape Girardeau County

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau

10/10 Excellent

Best breakfast I’ve had in a long time at a hotel. The variety was nice too!
United States
Lafonzel A
Reviewed November 4, 2026
Drury Plaza Hotel Cape Girardeau Conference Center

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