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Our top choices for Charleston hotels

Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (616)
This Charleston motel offers complimentary on-the-go breakfast and WiFi for a hassle-free stay. Guests appreciate the helpful staff and free parking. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
"Staff was great! Room was nice. "
United States
Lana
The price is ￥9,724
￥10,791 total
includes taxes & fees
Jan 7 - Jan 8
Super 8 by Wyndham Charleston/Sikeston East MO
Room, 1 King Bed, Non Smoking | View from room
Eagle Inn Charleston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
Discover relaxation at this Charleston motel offering complimentary WiFi and parking. The onsite health club provides fitness options after exploring local attractions. Cape Girardeau Municipal Airport is just a 43-minute drive away.
"Middle of nowhere hotel was ok"
United States
David
The price is ￥9,473
￥10,513 total
includes taxes & fees
Jan 7 - Jan 8
Eagle Inn Charleston
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1000)
Explore Shawnee National Forest from this Cape Girardeau hotel offering complimentary breakfast, WiFi, and parking. Enjoy the indoor pool and hot tub after a day out, or dine at The Southerner restaurant. Each room includes handy refrigerators and microwaves.
"This is one of the best properties. We are in the area often, it's the best."
United States
James
The price is ￥14,092
￥15,896 total
includes taxes & fees
Jan 11 - Jan 12
Drury Plaza Hotel Cape Girardeau Conference Center
Indoor pool, outdoor pool
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1005)
Located just off the highway near Sikeston dining and shopping, this hotel offers both indoor and outdoor pools for year-round swimming. Guests praise the peaceful atmosphere, helpful staff, and complimentary breakfast, parking, and WiFi.
"Great place. Friendly staff clean"
United States
Jeff
The price is ￥14,092
￥16,201 total
includes taxes & fees
Jan 11 - Jan 12
Drury Inn & Suites Sikeston, MO
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1007)
Located in Sikeston, this hotel offers an indoor pool for relaxing swims after a day of exploring. Near Central Park and the Sikeston Depot Museum, guests praise the delicious free breakfast and attentive service.
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ￥10,514
￥11,983 total
includes taxes & fees
Jan 18 - Jan 19
Best Western Plus Sikeston
Basic Double Room | Living area
La Center Motel

La Center Motel

La Center Motel
2.0 star property
La Center
7.8 out of 10, Good, (17)
Just 15 minutes from Ohio River Valley, this La Center hotel offers convenient amenities including complimentary WiFi and parking. Easy access to Paducah and Barkley Regional Airport makes exploration effortless.
"Quiet and convenient."
United States
Alma
La Center Motel
Front of property
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1007)
This peaceful hotel offers a quiet atmosphere just minutes from Shawnee National Forest and Cape Splash Family Aquatic Center. Nearby restaurants and stores enhance convenience while helpful staff ensure a comfortable stay with free WiFi and daily housekeeping.
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is ￥10,960
￥12,365 total
includes taxes & fees
Jan 11 - Jan 12
Pear Tree Inn Cape Girardeau Near the Medical Center
Individually decorated, individually furnished, desk, blackout drapes
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (727)
Enjoy tranquil accommodations at this welcoming Sikeston hotel where helpful staff receive consistent praise. Located near Central Park and Sikeston Depot Museum, guests appreciate the quiet atmosphere, clean rooms, and daily continental breakfast.
"Clean room and easy access to room"
United States
Anne
The price is ￥8,690
￥9,906 total
includes taxes & fees
Jan 7 - Jan 8
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
This centrally located hotel offers convenient access to restaurants and shopping. Take advantage of the indoor pool and fitness center after exploring nearby Cape Splash Family Aquatic Center. Free breakfast, WiFi, and parking enhance your stay with attentive staff ready to assist.
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
The price is ￥14,877
￥16,784 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (275)
Start your day with complimentary full breakfast before exploring nearby attractions. This hotel provides free WiFi and parking, making it an ideal base for visiting Fort Defiance State Park and Ballard Wildlife Management Area.
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
The price is ￥11,142
￥12,366 total
includes taxes & fees
Jan 24 - Jan 25
Quality Inn Cairo I-57
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (477)
Wake up to Mississippi River views at this downtown hotel, steps from Riverfront Park and Shawnee National Forest. After exploring, return to The Bistro for American cuisine or unwind at the bar. The 24-hour fitness center and in-room refrigerators enhance your stay.
"Very nice hotel within walking distance to many good restaurants "
United States
Vicky
The price is ￥18,949
￥21,472 total
includes taxes & fees
Jan 25 - Jan 26
Courtyard by Marriott Cape Girardeau Downtown
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (457)
Take a refreshing dip in the indoor pool or maintain your routine at the fitness center. Free breakfast, WiFi, and parking enhance your stay. Central Park and Sikeston Depot Museum are just moments away from this welcoming retreat.
"Very clean and super friendly staff!"
United States
Katherine
The price is ￥16,095
￥18,223 total
includes taxes & fees
Jan 25 - Jan 26
Hampton Inn Sikeston
House (2 Bedrooms) | Interior
Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is ￥18,949
￥45,410 total
includes taxes & fees
Jan 16 - Jan 17
Quiet Country Stay: Modern Home Near Paducah
Indoor pool, outdoor pool
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1010)
Escape to this serene retreat with both indoor and outdoor pools for year-round enjoyment. The fitness center keeps your routine intact while complimentary breakfast energizes your day exploring nearby Central Park and Sikeston Depot Museum.
"Very clean, very friendly! We will be staying again. "
United States
Beth
The price is ￥11,743
￥13,500 total
includes taxes & fees
Jan 11 - Jan 12
Pear Tree Inn Sikeston
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (484)
Located near Riverfront Park and Isle Casino, this business-friendly hotel offers exciting gaming, 2 restaurants including Beacon 53 for American cuisine, plus free WiFi and parking for convenient exploration of Cape Girardeau.
" Excellent stay. Will come again"
United States
joydeep
The price is ￥14,176
￥15,993 total
includes taxes & fees
Jan 8 - Jan 9
The Riverview
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (283)
Experience refreshing comfort at this Sikeston hotel with an indoor swimming pool and fitness center. Near Central Park and Sikeston Depot Museum, travelers appreciate the helpful staff, complimentary WiFi, and free parking for a convenient, stress-free stay.
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is ￥13,843
￥15,778 total
includes taxes & fees
Jan 11 - Jan 12
Comfort Inn & Suites Sikeston I-55
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (148)
Enjoy free continental breakfast and complimentary parking at this modern Cape Girardeau retreat. The indoor pool offers year-round swimming, while Fort D Historic Site and Cape Splash Family Aquatic Center are just minutes away.
"Lovely staff clean hotel comfortable beds "
United States
Kastriot
The price is ￥13,781
￥15,547 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites by Marriott Cape Girardeau
Free daily buffet breakfast
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
Wake up to complimentary breakfast at this quiet retreat near Shawnee National Forest. Guests love the peaceful atmosphere, helpful staff, and convenient location close to Cape Splash Family Aquatic Center. Free WiFi and parking enhance the overall value.
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is ￥10,960
￥12,365 total
includes taxes & fees
Jan 11 - Jan 12
Pear Tree Inn Cape Girardeau West
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (445)
Discover comfort at this Sikeston hotel with an indoor pool and fitness center. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby Central Park and Sikeston Depot Museum. Guests consistently praise the helpful staff and immaculate rooms.
"Stay was excellent "
United States
Kourtney
The price is ￥14,564
￥16,490 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express & Suites Sikeston Southwest by IHG
Free daily buffet breakfast
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1012)
Walking distance to restaurants and shops, this peaceful hotel offers complimentary breakfast, WiFi, and parking. Swim year-round in the indoor pool or unwind in the hot tub after exploring nearby attractions like Cape Splash Family Aquatic Center.
"Awesome stay!"
United States
Breckin
The price is ￥14,092
￥15,896 total
includes taxes & fees
Jan 11 - Jan 12
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Charleston

Quaint Charleston is calling! Discover its opera, entertainment, cathedral, and more.

See all hotels in Charleston
Cypress Trees on the Horizon. A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky.

Top Charleston Hotel Reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"Everyone kind & place very clean. "
Dawn 1-night trip
Posted 3 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

More cheap stays in Charleston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is ￥9,850 per night from Jan 11 to Jan 12
￥9,850
￥11,227 total
Jan 11 - Jan 12
includes taxes & fees
7.2/10 Good! (1,001 reviews)

Frequently asked questions

Where is the best place for a stay in Charleston?
Quality Inn Charleston - Sikeston is a favorite with Expedia customers. This hotel offers free breakfast and free parking. Reviews from our site also recommend Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston as top options for your trip. See all available top hotels, or vacation rentals in Charleston.
What's the top vacation rental that Charleston has to offer?
Little Blue Cottage on Spanish: Visitors like this Charleston vacation home rental. It comes with WiFi so you can feel at home during your trip. See all vacation rentals in Charleston.
If I need to cancel my hotel reservation in Charleston, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Charleston.
Where can I learn more about changing or cancelling my trip to Charleston?
To find more details about changing or cancelling your trip to Charleston, click here.
What's the best pet-friendly hotel in Charleston?
Quality Inn Charleston - Sikeston is a top hotel for people traveling with their pets, and offers free WiFi for its human guests. Two other good options for you and your pet's trip include Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston. See more pet-friendly hotel accommodations in Charleston.
What's the best accommodation near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
How is it to stay in Charleston?
Visitors to Charleston are sure to enjoy the restaurants. Tourists can also enjoy the city's entertainment choices, theaters, and churches. In Charleston, there are 3 hotels and other accommodations to choose from. Find out more about Charleston.
What are the top places to visit in Charleston?
The picturesque setting of Mississippi River and Ohio River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and Ballard Wildlife Management Area in the area. Check out what more to see and do in Expedia's Charleston guide.
What's the seasonal weather like in Charleston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Charleston is 59 inches.