Photo by Ryan Coleman

Find hotels in Sikeston, MO from ¥9,937

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Compare 276 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (436)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is ¥14,879
¥16,847 total
includes taxes & fees
Dec 7 - Dec 8
Hampton Inn Sikeston

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1006)
"Clean room, great location and friendly staff"
United States
Mark
The price is ¥14,059
¥16,163 total
includes taxes & fees
Dec 4 - Dec 5
Drury Inn & Suites Sikeston, MO

Days Inn and Suites by Wyndham Sikeston

2.0 star property
Sikeston
7.2 out of 10, Good, (1007)
"A great stay in every aspect. "
United States
Gertrude
The price is ¥9,827
¥11,200 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn and Suites by Wyndham Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1005)
"Everything was clean, staff was friendly "
United States
Matthew
The price is ¥12,028
¥13,826 total
includes taxes & fees
Dec 4 - Dec 5
Pear Tree Inn Sikeston

Best Western Plus Sikeston

2.5 star property
Sikeston
8.4 out of 10, Very Good, (1005)
"Very convenient and great breakfast "
United States
Duwaine
The price is ¥11,673
¥13,305 total
includes taxes & fees
Nov 30 - Dec 1
Best Western Plus Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very Good, (714)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is ¥9,827
¥11,201 total
includes taxes & fees
Nov 30 - Dec 1
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
Sikeston
8.6 out of 10, Excellent, (440)
"Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great."
United States
Kristen
The price is ¥14,879
¥16,846 total
includes taxes & fees
Dec 7 - Dec 8
Holiday Inn Express & Suites Sikeston Southwest by IHG

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
Sikeston
9.2 out of 10, Wonderful, (37)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is ¥15,779
¥17,865 total
includes taxes & fees
Dec 4 - Dec 5
Fairfield Inn & Suites by Marriott Sikeston

Country Yard Inn and Suite

2.0 star property
Sikeston
6.8 out of 10, (117)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is ¥8,352
¥9,937 total
includes taxes & fees
Nov 29 - Nov 30
Country Yard Inn and Suite

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1011)
"This was a wonderful stay. We will definitely stay again when we are in town!"
United States
Trista
The price is ¥12,966
¥13,708 total
includes taxes & fees
Dec 29 - Dec 30
Drury Inn & Suites Jackson MO

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
Sikeston
6.6 out of 10, (561)
"The room was good a/c kept it cold "
United States
Mary
The price is ¥9,034
¥10,297 total
includes taxes & fees
Nov 30 - Dec 1
Super 8 by Wyndham Sikeston/Miner Area

TownePlace Suites by Marriott Sikeston

3.0 star property
Sikeston
9.0 out of 10, Wonderful, (7)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is ¥17,802
¥20,157 total
includes taxes & fees
Dec 7 - Dec 8
TownePlace Suites by Marriott Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (654)
"Stayed on our way south for vacation. It was a clean nice place to stay. "
United States
Joel
The price is ¥13,147
¥14,228 total
includes taxes & fees
Dec 29 - Dec 30
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1007)
"Great stay"
United States
Heather
The price is ¥10,935
¥12,336 total
includes taxes & fees
Dec 3 - Dec 4
Pear Tree Inn Cape Girardeau West

Comfort Inn & Suites Sikeston I-55

2.5 star property
Sikeston
8.4 out of 10, Very Good, (280)
"Room was clean, breakfast was very good. "
United States
Connie
The price is ¥13,152
¥14,990 total
includes taxes & fees
Dec 7 - Dec 8
Comfort Inn & Suites Sikeston I-55

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is ¥10,935
¥12,336 total
includes taxes & fees
Dec 26 - Dec 27
Pear Tree Inn Cape Girardeau Near the Medical Center

Drury Inn & Suites Cape Girardeau

3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1005)
"Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. "
United States
Sandra
The price is ¥14,059
¥15,859 total
includes taxes & fees
Dec 26 - Dec 27
Drury Inn & Suites Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
"Very nice stay."
United States
Charity
The price is ¥14,059
¥15,859 total
includes taxes & fees
Dec 29 - Dec 30
Drury Plaza Hotel Cape Girardeau Conference Center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1005)
"It was right off the interstate with lots of restaurant options "
United States
Kelly
The price is ¥14,873
¥16,779 total
includes taxes & fees
Dec 26 - Dec 27
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Dexter Inn

2.5 star property
Dexter
7.0 out of 10, Good, (332)
"Room was nice and spacious."
United States
Rebecca
The price is ¥10,128
¥11,373 total
includes taxes & fees
Nov 29 - Nov 30
Dexter Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Stay near popular Sikeston attractions

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

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Frequently asked questions

Where is the best place to stay in Sikeston?
Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in Sikeston.
What are some of the best vacation rentals in Sikeston?
On the Wine Trail Hot Tub Wi-Fi : This vacation home rental outside of Sikeston is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
Where can I learn more about changing or cancelling my trip to Sikeston?
For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.
What's the best hotel for a family vacation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.
What is the top LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best pet-friendly accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Days Inn and Suites by Wyndham Sikeston and Pear Tree Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.
Where is the best hotel to stay close to Central Park?
Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.
What about the best place to stay close to Sikeston Depot Museum?
One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.
What are some accommodations with pools in Sikeston?
Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.
What's the best place to stay near Barkley Regional Airport (PAH)?
Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.
What is staying in Sikeston like?
Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.
What are the top places to visit in Sikeston?
A couple of favorite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.
What's the seasonal weather like in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.

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