Photo by Ryan Coleman

Find hotels in Sikeston, MO from ¥8,652

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Compare 277 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Sikeston hotels

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1019)
"Very nice hotel and nice staff "
The price is ¥13,283
¥14,983 total
includes taxes & fees
Oct 2 - Oct 3
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1016)
"Was a clean room, nice staff, good parking "
The price is ¥13,283
¥14,043 total
includes taxes & fees
Sep 28 - Sep 29
Drury Inn & Suites Jackson MO

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (1000)
"Excellent place. Really friendly staff"
The price is ¥13,283
¥14,983 total
includes taxes & fees
Sep 29 - Sep 30
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1012)
"Everything was extremely nice"
The price is ¥13,283
¥15,271 total
includes taxes & fees
Sep 29 - Sep 30
Drury Inn & Suites Sikeston, MO

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (451)
"The Staff was friendly The restaurant was good"
The price is ¥18,451
¥20,906 total
includes taxes & fees
Oct 19 - Oct 20
Courtyard by Marriott Cape Girardeau Downtown

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1007)
"I love this hotel! Have stayed several times and will definitely stay again. The rooms are always very clean and the staff is so friendly and helpful. I highly recommend this hotel!"
The price is ¥11,364
¥13,063 total
includes taxes & fees
Sep 28 - Sep 29
Pear Tree Inn Sikeston

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (65)
"Great overall stay"
The price is ¥14,931
¥16,992 total
includes taxes & fees
Sep 30 - Oct 1
Tru By Hilton Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (128)
"The hotel was very clean and updated and the staff was super friendly and very informative!"
The price is ¥13,728
¥15,486 total
includes taxes & fees
Oct 2 - Oct 3
Fairfield Inn & Suites by Marriott Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1009)
"My room was clean and I was very close to shopping and restaurants. I really enjoyed my stay there."
The price is ¥10,331
¥11,655 total
includes taxes & fees
Sep 28 - Sep 29
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1009)
"Staff was friendly, room was clean, good location, good rate."
The price is ¥10,331
¥11,655 total
includes taxes & fees
Sep 28 - Sep 29
Pear Tree Inn Cape Girardeau Near the Medical Center

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (623)
"Excellent place to stay. Breakfast was good and staff was friendly. "
The price is ¥12,421
¥13,443 total
includes taxes & fees
Sep 28 - Sep 29
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"It was right off the interstate with lots of restaurant options "
The price is ¥14,909
¥16,820 total
includes taxes & fees
Oct 2 - Oct 3
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (747)
"Would prefer onsite restaurant and bar"
The price is ¥16,185
¥18,260 total
includes taxes & fees
Oct 5 - Oct 6
Hampton Inn Cape Girardeau I 55 East

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
9.4 out of 10, Exceptional, (25)
"Hotel was clean, the toilets could use some attention, but staff was friendly and the breakfast was good"
The price is ¥14,909
¥16,882 total
includes taxes & fees
Oct 5 - Oct 6
Fairfield Inn & Suites by Marriott Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (682)
"This is a great place to stay and the staff are super friendly. The manager helped me with a double booking issue and was able to get me a refund which is amazing! Good clean place to stay."
The price is ¥7,590
¥8,652 total
includes taxes & fees
Oct 5 - Oct 6
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1013)
"This is such a nice clean place to stay. Breakfast was really good and the staff so nice and helpful. "
The price is ¥11,793
¥13,441 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Plus Sikeston

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (398)
"Nice property and friendly staff."
The price is ¥15,684
¥17,759 total
includes taxes & fees
Oct 5 - Oct 6
Hampton Inn Sikeston

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (271)
"The facility was very nice. "
The price is ¥13,049
¥14,872 total
includes taxes & fees
Oct 1 - Oct 2
Comfort Inn & Suites Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (431)
"Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great."
The price is ¥15,499
¥17,549 total
includes taxes & fees
Oct 3 - Oct 4
Holiday Inn Express & Suites Sikeston Southwest by IHG

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (734)
"Great area, fast check in, quiet, very spacious"
The price is ¥13,137
¥14,218 total
includes taxes & fees
Oct 5 - Oct 6
Comfort Suites Jackson-Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

More cheap stays in Sikeston

More cheap stays in Sikeston

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen: This vacation home rental outside of Sikeston is located in the city center and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a hot tub. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best pet-friendly accommodation in Sikeston?

Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

A couple of favorite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.

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