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Check prices for these dates

Tonight
Feb 27 - Feb 28
Tomorrow
Feb 28 - Mar 1
This weekend
Feb 27 - Mar 1
Next weekend
Mar 6 - Mar 8

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Our top choices for Sikeston hotels

Lobby

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (19 reviews)
"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
The price is ￥21,083
￥23,784 total
includes taxes & fees
Mar 5 - Mar 6
Rockwood Inn
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
The price is ￥14,184
￥16,002 total
includes taxes & fees
Mar 15 - Mar 16
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby sitting area

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (513 reviews)
"The room was clean and I was able to check in a bit early."
United States
Sara
The price is ￥13,659
￥15,409 total
includes taxes & fees
Mar 15 - Mar 16
The Riverview
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (490 reviews)
"Very nice hotel!"
United States
Angie
The price is ￥18,081
￥20,488 total
includes taxes & fees
Mar 22 - Mar 23
Courtyard by Marriott Cape Girardeau Downtown
Lobby

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (794 reviews)
"Excellent stay"
United States
Christina
The price is ￥16,488
￥18,600 total
includes taxes & fees
Mar 15 - Mar 16
Hampton Inn Cape Girardeau I 55 East
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (160 reviews)
"Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. "
United States
Richard
The price is ￥14,496
￥16,354 total
includes taxes & fees
Mar 12 - Mar 13
Fairfield Inn & Suites by Marriott Cape Girardeau
Snack bar

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (113 reviews)
"It was a nice stay"
United States
Douglas
The price is ￥15,210
￥17,311 total
includes taxes & fees
Mar 9 - Mar 10
Tru By Hilton Cape Girardeau
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,002 reviews)
"Great place "
United States
Kelly
The price is ￥15,585
￥17,582 total
includes taxes & fees
Mar 5 - Mar 6
Drury Plaza Hotel Cape Girardeau Conference Center
Free daily buffet breakfast

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"Awesome stay!"
United States
Breckin
The price is ￥14,027
￥15,826 total
includes taxes & fees
Mar 5 - Mar 6
Drury Inn & Suites Cape Girardeau
Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
"As always it was a perfect visit"
United States
John
The price is ￥14,650
￥16,844 total
includes taxes & fees
Mar 8 - Mar 9
Drury Inn & Suites Sikeston, MO
Lobby

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (12 reviews)
"Great stay "
United States
Ashley
The price is ￥15,210
￥17,079 total
includes taxes & fees
Mar 8 - Mar 9
Hampton Inn By Hilton Dexter
Exterior

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (897 reviews)
"Room was clean and spacious."
United States
George
The price is ￥12,096
￥14,502 total
includes taxes & fees
Mar 4 - Mar 5
Candlewood Suites Cape Girardeau by IHG
Desk, laptop workspace, blackout drapes, free cribs/infant beds

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,002 reviews)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is ￥11,221
￥12,658 total
includes taxes & fees
Mar 9 - Mar 10
Pear Tree Inn Cape Girardeau West
Lobby

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (701 reviews)
"The room was clean and nice. The breakfast was really good."
United States
Kalani
The price is ￥10,381
￥11,712 total
includes taxes & fees
Mar 9 - Mar 10
Quality Inn Cape Girardeau North
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (711 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is ￥13,116
￥14,195 total
includes taxes & fees
Mar 2 - Mar 3
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (486 reviews)
"Very Clean room, friendly staff, breakfast in the morning. Will be staying again! "
United States
Affinity
The price is ￥14,826
￥16,787 total
includes taxes & fees
Mar 7 - Mar 8
Hampton Inn Sikeston
Breakfast, lunch, dinner served; American cuisine

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (395 reviews)
"Clean room, friendly staff and quiet stay."
United States
Margo
The price is ￥13,093
￥14,702 total
includes taxes & fees
Mar 5 - Mar 6
Travelodge by Wyndham Dexter
Desk, iron/ironing board, free WiFi, bed sheets

Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (256 reviews)
"Old building water was not hot No locks on exterior doors Not a very well lit parking lot Bed was clean "
United States
Patrick
The price is ￥7,948
￥8,923 total
includes taxes & fees
Mar 28 - Mar 29
Econo Lodge Dexter
Desk, free WiFi

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (211 reviews)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is ￥10,911
￥12,746 total
includes taxes & fees
Feb 28 - Mar 1
Town House Inn Cape Giradreau
Free daily full breakfast

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,002 reviews)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ￥12,739
￥14,519 total
includes taxes & fees
Mar 26 - Mar 27
Best Western Plus Sikeston I-55
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Sikeston attractions

Central Park

3.8/5 (36 reviews)
Central Park offers a peaceful retreat with playgrounds and open spaces for Sikeston families. Bring a blanket for a relaxing picnic or watch children enjoy the recreational facilities.
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Sikeston Depot Museum

3.8/5 (33 reviews)
Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.
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Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston
Pre-teen girl walking through corn maze during fall

Top Sikeston Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"This was a great choice of hotels! Friendly staff, great dinner and breakfast - all complimentary. Room was spacious and comfortable. Spotless and such a comfy bed! Don’t miss out on staying here!"
Margaret 1-night trip
Posted 20 hours ago
Drury Inn & Suites Cape Girardeau

More cheap stays in Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is ￥10,997 per night from Mar 1 to Mar 2
￥10,997
￥12,535 total
Mar 1 - Mar 2
includes taxes & fees
7.2/10 Good! (1,001 reviews)

Frequently asked questions

Where is the best place to stay in Sikeston?
Fairfield Inn & Suites by Marriott Sikeston is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Other top choices based on reviews include Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO. See all available top hotels, or vacation rentals in Sikeston.
What are some of the best vacation rentals in Sikeston?
Beautiful location in the secluded woods: This vacation home rental outside of Sikeston offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
Where can I learn more about changing or cancelling my trip to Sikeston?
For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.
What's the best hotel for a family vacation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Find more child-friendly accommodations in Sikeston.
What is the top LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best pet-friendly accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Best Western Plus Sikeston I-55 and Hampton Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.
Where is the best hotel to stay close to Central Park?
Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.
What about the best place to stay close to Sikeston Depot Museum?
One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.
What are some accommodations with pools in Sikeston?
Best Western Plus Sikeston I-55 is a top hotel with a pool, free full breakfast, and free parking. TownePlace Suites by Marriott Sikeston is one more option that features an onsite pool. View all hotels with pools in Sikeston.
What's the best place to stay near Barkley Regional Airport (PAH)?
Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.
What is staying in Sikeston like?
Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.
What are the top places to visit in Sikeston?
A couple of favorite places to visit are Central Park and Sikeston Depot Museum. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Check out what more to see and do in Expedia's Sikeston guide.
What's the seasonal weather like in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.