Default HTG hotel image

Find hotels in Matthews, MO from ￥8,739

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 24 - Aug 25
Tomorrow
Aug 25 - Aug 26
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Filter by

Property class

Guest rating

Our top choices for Matthews hotels

Exterior
Breakfast area
Pool
Exterior

1. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Jeffrey
￥15,870
￥17,970 total
includes taxes & fees
Aug 30 - Aug 31
Hampton Inn Sikeston
Pool
Property amenity
Restaurant
Lobby

2. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Sally
￥14,940
￥17,177 total
includes taxes & fees
Aug 30 - Aug 31
Drury Inn & Suites Sikeston, MO
Exterior
Breakfast meal
Pool
Room

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
michael
￥16,690
￥18,897 total
includes taxes & fees
Aug 30 - Aug 31
Holiday Inn Express & Suites Sikeston Southwest by IHG
Property amenity
View from property
Lobby
Pool

4. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
￥16,054
￥18,178 total
includes taxes & fees
Aug 30 - Aug 31
Fairfield Inn & Suites by Marriott Sikeston
Room, 1 King Bed, Accessible, Non Smoking
Room
Suite, 2 Queen Beds, Non Smoking
Exterior

5. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
Kevin
￥9,728
￥11,090 total
includes taxes & fees
Aug 25 - Aug 26
Super 8 by Wyndham Sikeston/Miner Area
Room
Living area
Exterior
Interior

6. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
United States
Sharika West
￥9,906
￥11,291 total
includes taxes & fees
Aug 25 - Aug 26
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Breakfast area
Exterior
Pool
Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)

7. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Kevin
￥14,185
￥16,166 total
includes taxes & fees
Aug 30 - Aug 31
Best Western Plus Sikeston I-55
Room
Exterior
Restaurant
Lobby

8. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
Lori
￥10,403
￥11,859 total
includes taxes & fees
Aug 27 - Aug 28
Days Inn and Suites by Wyndham Sikeston
Property amenity
Studio, 1 King Bed with Sofa bed
Bar (on property)
Exterior

9. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Lauren
￥18,756
￥21,237 total
includes taxes & fees
Sep 3 - Sep 4
TownePlace Suites by Marriott Sikeston
Room, 1 Queen Bed, Non Smoking
Suite, 1 King Bed, Non Smoking
Exterior
Lobby

10. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
Marston
United States
Rachel
￥13,161
￥15,034 total
includes taxes & fees
Aug 27 - Aug 28
Super 8 By Wyndham Marston
Exterior
Room
Lobby
Breakfast area

11. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
United States
Lakeysha
￥14,350
￥16,355 total
includes taxes & fees
Sep 13 - Sep 14
Comfort Inn & Suites Sikeston I-55
Room
Room
Exterior
Lobby

12. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
United States
William
￥8,872
￥10,557 total
includes taxes & fees
Sep 16 - Sep 17
Country Yard Inn and Suite
Exterior
Breakfast buffet
Lobby sitting area
Reception

13. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Bobby
￥10,569
￥11,728 total
includes taxes & fees
Sep 7 - Sep 8
The Riverstone Hotel Charleston-Sikeston
Dining
Lobby
Fitness facility
Room, 1 King Bed, Accessible, Non Smoking

14. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
United States
Steven
￥13,876
￥15,580 total
includes taxes & fees
Aug 27 - Aug 28
Travelodge by Wyndham Dexter
Room
Lobby
Front of property - evening/night
Lobby

15. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
France
￥9,458
￥10,496 total
includes taxes & fees
Aug 30 - Aug 31
Super 8 by Wyndham Charleston/Sikeston East MO
Breakfast area
Breakfast area
Hallway
Reception

16. Dexter Inn

Dexter Inn
Dexter
United States
Cynthia
￥9,919
￥11,138 total
includes taxes & fees
Aug 25 - Aug 26
Dexter Inn
Room
Lobby
Exterior
Room

17. Econo Lodge Dexter

Econo Lodge Dexter
Dexter
United States
Herman
￥8,105
￥9,101 total
includes taxes & fees
Sep 23 - Sep 24
Econo Lodge Dexter
Room
View from room
Room
Breakfast area

18. Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
Marston
United States
Frank
￥7,649
￥8,739 total
includes taxes & fees
Sep 23 - Sep 24
Travel Inn Marston I-55 by Hotel O
Lobby
Lobby
Reception
Exterior

19. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Joyce
￥15,510
￥17,417 total
includes taxes & fees
Aug 30 - Aug 31
Hampton Inn By Hilton Dexter
Room, 1 King Bed, Non Smoking | View from room
Room, 1 King Bed, Non Smoking | Bathroom
Room
Property entrance

20. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
￥11,014
￥12,224 total
includes taxes & fees
Aug 25 - Aug 26
Eagle Inn Charleston
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Matthews Hotel Reviews

Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"👍"
Gregory S 1-night trip
Posted 14 hours ago
Hampton Inn Sikeston
Econo Lodge Dexter

Econo Lodge Dexter

10/10 Excellent
"Staff are kind, welcoming and helpful! Property is clean and well. For the pri"
Elizabeth 1-night trip
Posted 1 day ago
Econo Lodge Dexter
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Great value, very clean and breakfast was actually good."
Ken 1-night trip
Posted 2 days ago
Drury Inn & Suites Sikeston, MO
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"Good price."
Kevin 1-night trip
Posted 2 days ago
Super 8 by Wyndham Sikeston/Miner Area
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"
Cheyenna 1-night trip
Posted 4 days ago
Days Inn and Suites by Wyndham Sikeston
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent
"Best Hampton Inn that I have ever stayed in. Excellent service and Wonderful staff. Extremely helpful with disabled husband."
Stephen 2-night trip
Posted 4 days ago
Hampton Inn By Hilton Dexter
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

10/10 Excellent
"It’s was clean and very well maintained"
Larry 1-night trip
Posted 7 days ago
Travelodge by Wyndham Dexter
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent
"Nice staff. Very accommodating."
Domingo 1-night trip
Posted 2 weeks ago
Super 8 by Wyndham Charleston/Sikeston East MO

More cheap stays in Matthews

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO
￥9,458
￥10,496 total
Aug 30 - Aug 31
includes taxes & fees
Super 8 by Wyndham Charleston/Sikeston East MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
￥10,403
￥11,859 total
Aug 27 - Aug 28
includes taxes & fees
7.2/10 Good! (1,004 reviews)
Days Inn and Suites by Wyndham Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO
￥14,185
￥16,166 total
Aug 30 - Aug 31
includes taxes & fees
8.4/10 Very Good! (1,015 reviews)
Best Western Plus Sikeston I-55
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2179 Gill Plaza Drive Dexter MO
￥15,510
￥17,417 total
Aug 30 - Aug 31
includes taxes & fees
9.8/10 Exceptional! (66 reviews)
Hampton Inn By Hilton Dexter
Hampton Inn Sikeston

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO
￥15,870
￥17,970 total
Aug 30 - Aug 31
includes taxes & fees
9/10 Wonderful! (615 reviews)
Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO
￥16,690
￥18,897 total
Aug 30 - Aug 31
includes taxes & fees
Holiday Inn Express & Suites Sikeston Southwest by IHG

Frequently asked questions

Where is the best place for a stay in Matthews?
Drury Inn & Suites Sikeston, MO, located 9.7 mi (15.5 km) from the heart of Matthews, is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in Matthews.
What are some of the best vacation rentals in Matthews?
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This vacation home rental near Matthews offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. See all vacation rentals in Matthews.
If I need to cancel my hotel reservation in Matthews, will I receive a refund?
Yes, the majority of hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Matthews.
Where can I learn more about changing or cancelling my trip to Matthews?
To access more information about changing or cancelling your trip to Matthews, click here.
What's it like to stay in Matthews?
Travelers to Matthews will find plenty to explore and enjoy. There are 42 hotels and other accommodations in the surrounding area. Find out more about Matthews.
What should I see while I'm in Matthews?
Places to visit in the wider area include Sikeston Depot Museum, Big Oak Tree State Park, and Central Park. You'll also find Hunter-Dawson State Historic Site and River Ridge Winery in the area. Check out what more to see and do in Expedia's Matthews guide.
What's the weather like in Matthews?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Matthews is 60 inches.

Explore a world of travel with Expedia