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Oct 8 - Oct 9
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Oct 9 - Oct 10
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Oct 9 - Oct 11
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Our top choices for Matthews hotels

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

1. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Carolyn
￥16,653
￥18,938 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn Sikeston
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.
A kitchenette with a coffee machine, a kettle, and storage shelves.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

2. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
Melissa
￥14,378
￥16,351 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express & Suites Sikeston Southwest by IHG
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

3. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
￥15,958
￥18,148 total
includes taxes & fees
Oct 15 - Oct 16
Fairfield Inn & Suites by Marriott Sikeston
Property amenity
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

4. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Stacy
￥15,982
￥18,176 total
includes taxes & fees
Oct 18 - Oct 19
TownePlace Suites by Marriott Sikeston
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

5. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Scott
￥14,850
￥17,074 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites Sikeston, MO
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
Room

6. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Shelley
￥13,270
￥15,124 total
includes taxes & fees
Oct 11 - Oct 12
Best Western Plus Sikeston I-55
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
United States
Craig
￥9,771
￥11,136 total
includes taxes & fees
Oct 13 - Oct 14
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

8. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
David
￥10,475
￥11,939 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn and Suites by Wyndham Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.
A motel with a covered entrance, multiple rooms, and a parking lot.

9. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
William
￥9,025
￥10,286 total
includes taxes & fees
Oct 15 - Oct 16
Super 8 by Wyndham Sikeston/Miner Area
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.
A living room with two sofas, a coffee table, a TV, and a cabinet.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

10. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
United States
Kathryn
￥13,146
￥14,983 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Inn & Suites Sikeston I-55
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A bathroom with a bathtub, toilet, and shower curtain.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.
A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

11. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
United States
William
￥8,493
￥10,106 total
includes taxes & fees
Oct 13 - Oct 14
Country Yard Inn and Suite
A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.
A modern kitchen with a built-in microwave, a black refrigerator, and a wooden countertop.
A hotel with a central entrance, multiple parking spaces, and a well-lit facade.
A room with a brown leather sofa, a red chair, and a cityscape painting on the wall.

12. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
Marston
United States
Brenda
￥8,816
￥10,115 total
includes taxes & fees
Oct 21 - Oct 22
Super 8 By Wyndham Marston
A building with a fountain and flower beds in front.
A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.
A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

13. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Kathleen
￥10,505
￥11,764 total
includes taxes & fees
Oct 11 - Oct 12
The Riverstone Hotel Charleston-Sikeston
A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.
A hotel reception area with a reception desk, framed certificates, and a painting on the wall.
A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.
A living room with a sofa, a coffee table, a clock, and a painting on the wall.

14. Econo Lodge Dexter

Econo Lodge Dexter
Dexter
United States
Herman
￥8,056
￥9,127 total
includes taxes & fees
Nov 6 - Nov 7
Econo Lodge Dexter
A hotel room with two beds, a television, a desk, and a mirror.
A covered pavilion with a roof, wooden railing, and a barbecue grill.
A hotel room with a bed, a desk, a television, and a seating area with a small table.
A motel with a covered outdoor seating area and a parking lot.

15. Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
Marston
United States
Frank
￥6,912
￥8,346 total
includes taxes & fees
Oct 21 - Oct 22
Travel Inn Marston I-55 by Hotel O
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.
A bathroom with a sink, mirror, towel rack, shower, and toilet.

16. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
￥10,426
￥11,674 total
includes taxes & fees
Oct 9 - Oct 10
Eagle Inn Charleston
A modern hotel lobby with a bar area, seating, and artwork on the walls.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.
A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

17. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Kendall
￥15,418
￥17,466 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn By Hilton Dexter
A diner with booth seating, a checkered floor, and a counter with a cash register.
A gym with multiple exercise machines, a clock on the wall, and a window with blinds.
A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.
A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

18. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
United States
Steven
￥13,651
￥15,465 total
includes taxes & fees
Oct 18 - Oct 19
Travelodge by Wyndham Dexter
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A reception area with a counter, a flat-screen TV, and a window with blinds.
A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.
A hotel with a covered entrance, a sign for the brand, and a parking lot with cars.

19. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
William
￥9,401
￥10,528 total
includes taxes & fees
Oct 11 - Oct 12
Super 8 by Wyndham Charleston/Sikeston East MO
A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.
A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.
A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.
A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

20. Dexter Inn

Dexter Inn
Dexter
United States
Edward
￥10,420
￥11,806 total
includes taxes & fees
Oct 11 - Oct 12
Dexter Inn
View all properties

Hotels recommended for families in Matthews

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
￥16,653
￥18,938 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn Sikeston
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.
A kitchenette with a coffee machine, a kettle, and storage shelves.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
￥14,378
￥16,351 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express & Suites Sikeston Southwest by IHG
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
￥15,958
￥18,148 total
includes taxes & fees
Oct 15 - Oct 16
Fairfield Inn & Suites by Marriott Sikeston
Property amenity
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
￥15,982
￥18,176 total
includes taxes & fees
Oct 18 - Oct 19
TownePlace Suites by Marriott Sikeston
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
￥14,850
￥17,074 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites Sikeston, MO
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
Room

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
￥13,270
￥15,124 total
includes taxes & fees
Oct 11 - Oct 12
Best Western Plus Sikeston I-55
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
￥9,771
￥11,136 total
includes taxes & fees
Oct 13 - Oct 14
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
￥10,475
￥11,939 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn and Suites by Wyndham Sikeston
Save an average of 15% on thousands of hotels when you're signed in

Top Matthews Hotel Reviews

Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"Loved the modern, CLEAN, room and staff was extremely friendly and helpful. We were greeted and served by "Brittany" at check-in who was so nice and friendly and even gave us dinner suggestions. We would definitely stay here again!"
Deborah 1-night trip
Posted 3 hours ago
Hampton Inn Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Everything was up to par, good was excellent."
Samuel 1-night trip
Posted 3 hours ago
Drury Inn & Suites Sikeston, MO
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

8/10 Good
"Our room was very clean and comfy. The bathroom was clean but could use an update. The bathroom tissue and face tissues are on the thin side. Breafast bar was excellent. The staff was very nice and helpful."
Kathryn 1-night trip
Posted 2 days ago
Comfort Inn & Suites Sikeston I-55
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent
"Really nice place to look brand new that was good. TVs were updated. I enjoyed it. Thank you for having me."
Marcus 1-night trip
Posted 2 days ago
Hampton Inn By Hilton Dexter
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

8/10 Good
"Everything was good about the room except the bathroom. The stopper on the sink did not work and there was a dent in the wall. The face/wash towels need to be changed out. They are no longer white. They are dull in color. The couch needs to be cleaned and freshen. The staff was excellent and everything else is good. I just wish that breakfast offered hot eggs and meat vs. only waffles. Otherwise the room was good."
James 3-night trip
Posted 2 days ago
Days Inn and Suites by Wyndham Sikeston
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"Great place"
BRANDY 1-night trip
Posted 5 days ago
Super 8 by Wyndham Sikeston/Miner Area
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"NA NA NA NA NA NA NA NA NA NA NA NA NA"
Kevin 1-night trip
Posted 10 days ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

8/10 Good
"Very clean and a very friendly staff! Air conditioner in room wasn’t working perfectly so it felt very humid but overall was not bad. I would stay here again!"
Brenda 1-night trip
Posted 11 days ago
Super 8 By Wyndham Marston

More cheap stays in Matthews

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO
￥9,025
￥10,286 total
Oct 15 - Oct 16
includes taxes & fees
7/10 Good! (683 reviews)
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO
￥9,401
￥10,528 total
Oct 11 - Oct 12
includes taxes & fees
Super 8 by Wyndham Charleston/Sikeston East MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
￥10,475
￥11,939 total
Nov 1 - Nov 2
includes taxes & fees
7.2/10 Good! (1,000 reviews)
Days Inn and Suites by Wyndham Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO
￥13,270
￥15,124 total
Oct 11 - Oct 12
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)
Best Western Plus Sikeston I-55
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO
￥14,378
￥16,351 total
Nov 8 - Nov 9
includes taxes & fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
Hampton Inn Sikeston

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO
￥16,653
￥18,938 total
Oct 18 - Oct 19
includes taxes & fees
9/10 Wonderful! (632 reviews)
Hampton Inn Sikeston

Frequently asked questions

Where is the best place for a stay in Matthews?
Drury Inn & Suites Sikeston, MO, located 9.7 mi (15.5 km) from the heart of Matthews, is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in Matthews.
What are some of the best vacation rentals in Matthews?
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This vacation home rental near Matthews offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. See all vacation rentals in Matthews.
If I need to cancel my hotel reservation in Matthews, will I receive a refund?
Yes, the majority of hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Matthews.
Where can I learn more about changing or cancelling my trip to Matthews?
To access more information about changing or cancelling your trip to Matthews, click here.
What's it like to stay in Matthews?
Travelers to Matthews will find plenty to explore and enjoy. There are 42 hotels and other accommodations in the surrounding area. Find out more about Matthews.
What should I see while I'm in Matthews?
Places to visit in the wider area include Marston Community Center, Big Oak Tree State Park, and Sikeston Depot Museum. You'll also find New Madrid Historical Museum and Central Park in the area. Check out what more to see and do in Expedia's Matthews guide.
What's the weather like in Matthews?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Matthews is 60 inches.

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