Sikeston, MO

Travel Guide

Photo by Ryan Coleman
Photo by Ryan Coleman
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is ￥14,114 per night from Jan 11 to Jan 12
￥14,114
￥16,227 total
Jan 11 - Jan 12
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
We are on a road trip and this has been our best hotel so far. They serve free appetizers which is like a meal from 5:30- 7:00 pm with 3 free drinks per adult, yes free alcohol!!. And a great breakfast.. clean, modern, well kept and great staff and service ❤️❤️❤️❤️

Reviewed on Jan 1, 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is ￥15,831 per night from Jan 11 to Jan 12
￥15,831
￥17,924 total
Jan 11 - Jan 12
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (456 reviews)
We were stranded in Matthews, MO and this hotel was very accommodating to our situation. The staff were professional and friendly! The manager even had a staff member provide us with a ride to the nearest car rental place. The hotel was clean with great amenities! We even received a call after our ...

Reviewed on Dec 30, 2025

Hampton Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is ￥12,397 per night from Jan 9 to Jan 10
￥12,397
￥14,129 total
Jan 9 - Jan 10
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
Nice and affordable option! Quiet place with clean facility throughout. Great people and good service.

Reviewed on Dec 29, 2025

Best Western Plus Sikeston
See all 283 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beautiful location in the secluded woods

Beautiful location in the secluded woods

Pomona IL
Stay at this vacation home in Pomona. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Pomona Winery and Von Jakob Winery & Brewery are located ...
9.8/10 Exceptional! (61 reviews)
Yes, Kevin was communicative and helpful. The space was convenient for our family and the beds and kitchen clean. We will most likely rent again.

Reviewed on Nov 30, 2025

Beautiful location in the secluded woods
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna IL
Stay at this cabin in Anna. Enjoy a garden, patios, and cable/satellite TV service. Our guests praise the helpful staff and the property condition in our reviews. ...
9.8/10 Exceptional! (405 reviews)
Cabin was perfect, secluded and peaceful. Very clean and worked out great! Hoping to come back next year! Thank you for the great place!

Reviewed on Dec 10, 2025

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
New cabin in the woods with private hot tub

New cabin in the woods with private hot tub

Cobden IL
Stay at this cabin in Anna. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions StarView Vineyards and King Neptune Memorial are ...
9.8/10 Exceptional! (136 reviews)
Everything was cleam and in excellent shape,, hot tub was amazing, bedding etc.

Reviewed on Dec 2, 2025

New cabin in the woods with private hot tub
See all properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

City of Miner Convention Center

Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants.

City of Miner Convention Center

Sikeston Depot Museum

You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this relaxing area, you can savor the top-notch restaurants.

Sikeston Depot Museum

Central Park

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

Central Park

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