Name: Drury Plaza Hotel Cape Girardeau Conference Center
Price range: ￥13,223
Rating: 9.4

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St, Farmington, MO

￥7,682

￥8,746 total

Sep 2 - Sep 3

includes taxes & fees

Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...

8/10 Very Good! (1,002 reviews)

"I actually stay there a couple times a month. I do it for the pool most all their staff is very friendly jay is especially/. I would recommend it to anyone."

Reviewed on Aug 17, 2025

The Riverview

777 Main St, Cape Girardeau, MO

￥15,556

￥17,549 total

Aug 27 - Aug 28

includes taxes & fees

Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...

9.2/10 Wonderful! (394 reviews)

"This hotel was very pleasant. It was very nice and we liked the casino was downstairs."

Reviewed on Aug 23, 2025

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive, Cape Girardeau, MO

￥13,223

￥14,916 total

Sep 1 - Sep 2

includes taxes & fees

Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

9.4/10 Exceptional! (1,011 reviews)

"Kickback and breakfast was the best I’ve ever had at any hotel before including service."

Reviewed on Aug 24, 2025

See all 585 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Postcard Cabins St. Francois

7555 State Hwy Y, French Village, MO

Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.

9.8/10 Exceptional! (27 reviews)

"Our Postcard cabin was a joy. Peaceful, clean, well-stocked, and cool! Could not have been better."

Reviewed on Aug 15, 2025

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

4800 U.S. Highway 67, De Soto, MO

Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...

9.4/10 Exceptional! (150 reviews)

Family weekend

"My family and I enjoyed our relaxing weekend. The resort was pretty full but you wouldnt know it. Nothing we did was crowded. The pool and area around it was beautiful. The water crystal clear. The villa was quiet and clean."

Reviewed on Aug 25, 2025

Treehouse and Hot Tub on 10acres - Pet Friendly!

Dittmer

Stay at this cabin in Jefferson County. Enjoy an in-room coffeemaker, in-room fireplaces, and air conditioning.

9.2/10 Wonderful! (7 reviews)

Perfect Getaway

"The Den was the perfect weekend getaway! The host provided every thing that we possibly needed for our visit."

Reviewed on Mar 10, 2025

See all properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Taum Sauk Mountain in located in the St.Francis mountain range of south/central Missouri. It's also the highest point in Missouri. My kids are standing at the spot where the actual marker sign in

Elephant Rocks State Park

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

Beautiful area. Easy to get up close and not too far off the main road. 🏞 #waterfalls #nature #explore #missouri

Rocky Falls

Commune with nature and explore the great outdoors at Rocky Falls during your travels in Winona. While you're in the area, wander around the natural setting.

Breathtaking view at the dam by the road and some small trails for walking as well!

Lake Wappapello

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Century Casino Caruthersville

Why not roll the dice with a visit to Century Casino Caruthersville during your travels in Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

Current River State Park

Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.