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Check prices for these dates

This weekend
Jul 31 - Aug 2
Next weekend
Aug 7 - Aug 9

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Our top choices for Perryville hotels

Exterior

1. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (609 reviews)
"Breakfast was good nice beds very nice stay"
United States
scott
The price is ļæ„14,527
ļæ„16,631 total
includes taxes & fees
Aug 16 - Aug 17
Holiday Inn Express & Suites Perryville by IHG
Outdoor dining

2. Perryville RV Resort

Perryville RV Resort
2.0 star property
Perryville
10.0 out of 10, Exceptional, (2 reviews)
"We had a amazing time it was our 4 yr anniversary"
United States
Von
The price is ļæ„10,880
ļæ„12,454 total
includes taxes & fees
Aug 20 - Aug 21
Perryville RV Resort
Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes

3. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very Good, (1,004 reviews)
"Very nice clean hotel and room. Comfy bed and AC worked well in hot weather. Service at front desk was very friendly and helpful."
United States
Angela
The price is ļæ„11,281
ļæ„12,914 total
includes taxes & fees
Aug 11 - Aug 12
Super 8 by Wyndham Perryville
Room, 1 King Bed | Jetted tub

4. Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
6.8 out of 10, (448 reviews)
"Staff was super friendly and helpful. Beds were wonderful! We will be back."
United States
Wanda
The price is ļæ„11,060
ļæ„12,660 total
includes taxes & fees
Aug 2 - Aug 3
Days Inn by Wyndham Perryville
Interior

5. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.6 out of 10, Exceptional, (4 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor itemsā€¦all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
The price is ļæ„13,478
ļæ„27,446 total
includes taxes & fees
Aug 6 - Aug 7
The Atrium - A Boutique Hotel
Lobby

6. Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.8 out of 10, (136 reviews)
"Nice for a quick stay."
United States
Evelynmaryeka
The price is ļæ„12,453
ļæ„14,257 total
includes taxes & fees
Aug 2 - Aug 3
Quality Inn Perryville I-55
Coffee/tea maker, full-size fridge, microwave, oven

7. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
The price is ļæ„33,032
ļæ„50,957 total
includes taxes & fees
Jul 30 - Jul 31
Urban Lofts
Private kitchen

8. The Mediterranean House 1858

The Mediterranean House 1858
2.0 star property
Perryville
The price is ļæ„79,497
ļæ„130,228 total
includes taxes & fees
Aug 6 - Aug 7
The Mediterranean House 1858
Lobby

9. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,010 reviews)
"This hotel was so clean and comfy! The breakfast was awesome too!"
United States
Jamie
The price is ļæ„13,270
ļæ„14,029 total
includes taxes & fees
Aug 23 - Aug 24
Drury Inn & Suites Jackson MO
Exterior

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (813 reviews)
"Breakfast is good."
United States
Jkara
The price is ļæ„15,181
ļæ„16,430 total
includes taxes & fees
Jul 30 - Jul 31
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

11. Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.4 out of 10, Very Good, (411 reviews)
"Nice place"
United States
Doug
The price is ļæ„12,829
ļæ„14,238 total
includes taxes & fees
Aug 25 - Aug 26
Baymont by Wyndham Chester IL
Exterior

12. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (580 reviews)
"Great place to stay! New, comfortable. Friendly and knowledgeable staff, nice decor, convenient breakfast."
United States
David
The price is ļæ„15,751
ļæ„17,481 total
includes taxes & fees
Aug 16 - Aug 17
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Exterior

13. Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve
2.5 star property
Ste Genevieve
8.8 out of 10, Excellent, (661 reviews)
"Good location, li item ame cities, nice roomm good for economical overnight stay"
United States
MELINDA
The price is ļæ„14,009
ļæ„16,474 total
includes taxes & fees
Aug 16 - Aug 17
Microtel Inn & Suites by Wyndham Sainte Genevieve
Snack bar

14. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (156 reviews)
"The area and room looks great and clean. The service was excellent"
United States
Luis
The price is ļæ„15,305
ļæ„17,420 total
includes taxes & fees
Aug 5 - Aug 6
Tru By Hilton Cape Girardeau
Porch

15. Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (305 reviews)
"The owner of this place was extremely nice. So was the cleaning staff. I would definitely stay here again."
United States
Christine
The price is ļæ„14,328
ļæ„15,651 total
includes taxes & fees
Aug 18 - Aug 19
Madison Inn Lodge
Lobby

16. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (773 reviews)
"The room was in great shape"
United States
Tawanna
The price is ļæ„15,243
ļæ„16,497 total
includes taxes & fees
Aug 23 - Aug 24
Comfort Suites Jackson-Cape Girardeau
Standard room, 2 double beds. | Blackout drapes, soundproofing, iron/ironing board (on request)

17. Triangle Inn Motel

Triangle Inn Motel
2.0 star property
Ste Genevieve
8.2 out of 10, Very Good, (61 reviews)
"Fine stay, perfect for what I needed. Staff was very helpful and knowledgeable."
United States
Pamela
The price is ļæ„11,908
ļæ„14,005 total
includes taxes & fees
Aug 18 - Aug 19
Triangle Inn Motel
Exterior

18. The Conner House B&B

The Conner House B&B
3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (22 reviews)
"A pitch perfect stay"
United States
James
The price is ļæ„25,583
ļæ„28,392 total
includes taxes & fees
Aug 2 - Aug 3
The Conner House B&B
Classic Room, 1 King Bed | Down comforters, desk, laptop workspace, blackout drapes

19. Briarwood Inn of Sparta

Briarwood Inn of Sparta
2.5 star property
Sparta
7.4 out of 10, Good, (135 reviews)
"Location is good"
United States
Steve
The price is ļæ„12,935
ļæ„14,355 total
includes taxes & fees
Aug 24 - Aug 25
Briarwood Inn of Sparta
Desk, iron/ironing board, WiFi (free), bed sheets

20. Sparta Motel Near St. Louis / Mississippi River IL

Sparta Motel Near St. Louis / Mississippi River IL
2.0 star property
Sparta
4.4 out of 10, (69 reviews)
"Nice hotel, clean, huge pool"
United States
Stacey
The price is ļæ„11,470
ļæ„13,418 total
includes taxes & fees
Aug 24 - Aug 25
Sparta Motel Near St. Louis / Mississippi River IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

8.8/10 (19 reviews)
This serene Catholic shrine honors the Miraculous Medal with exquisite stained glass and intricate murals. Visitors find spiritual renewal along the peaceful Rosary Walk and Marian Grotto gardens.
See properties

Perryville and related destinations

Historic battlefields and the charming downtown district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Center and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend.

See all hotels in Perryville
A train crossing a stone bridge over a river, surrounded by lush greenery.

Top Perryville Hotel Reviews

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent
"As usual an excellent hotel! Helpful staff and very clean! Beds are very comfortable and breakfast is excellent!"
Todd 2-night trip
Posted 2 hours ago
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

More cheap stays in Perryville

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

1500 Liberty Street Perryville MO
The price is ļæ„11,060 per night from Aug 2 to Aug 3
ļæ„11,060
ļæ„12,660 total
Aug 2 - Aug 3
includes taxes & fees
6.8/10 (448 reviews)

Frequently asked questions

What's the best place for a stay in Perryville?
Days Inn by Wyndham Perryville is one of the top choices for your stay based on our traveler data. This hotel offers free breakfast and free parking. Other good choices for your trip include Holiday Inn Express & Suites Perryville by IHG and Super 8 by Wyndham Perryville. See all available top hotels, or vacation rentals in Perryville.
What are some of the best vacation rentals in Perryville?
Beautiful location in the secluded woods: This vacation home rental near Perryville offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in Perryville.
If I need to cancel my hotel reservation in Perryville, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Perryville.
Where can I learn more about changing or cancelling my trip to Perryville?
For additional details about picking new dates or cancelling your trip to Perryville, go to https://www.expedia.com/service/.
What is the top LGBTQ-friendly accommodation in Perryville?
Holiday Inn Express & Suites Perryville by IHG is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. See all available hotels listed as LGBTQ-friendly in Perryville.
What's the best pet-friendly place to stay in Perryville?
Days Inn by Wyndham Perryville is a top hotel for people traveling with their pets, and offers a seasonal outdoor pool and laundry facilities for its human guests. Other good choices for you and your pet include Super 8 by Wyndham Perryville and Perryville RV Resort. See more pet-friendly hotel accommodations in Perryville.
What's the best hotel to stay close to National Shrine of Our Lady of the Miraculous Medal?
Holiday Inn Express & Suites Perryville, an IHG Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 1.4 mi (2.3 km) from National Shrine of Our Lady of the Miraculous Medal. Other good options within a few miles include Super 8 by Wyndham Perryville and Days Inn by Wyndham Perryville.
What about the best place to stay near Missouri's National Veterans Memorial?
One of the top choices for your stay is Holiday Inn Express & Suites Perryville, an IHG Hotel, located 3.5 mi (5.6 km) from Missouri's National Veterans Memorial, and this hotel offers free breakfast and an indoor pool. Super 8 by Wyndham Perryville and Urban Lofts are a couple of other good options within a few miles.
What are some hotels with pools in Perryville?
Quality Inn Perryville I-55 is a top hotel with a seasonal outdoor pool, free breakfast, and free WiFi. View all hotels with pools in Perryville.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What is staying in Perryville like?
Visitors can enjoy all that Perryville has to offer including the wineries, golf courses, and coffeehouses. Tourists can also enjoy the city's festivals, university setting, and parks. In Perryville, there are 27 hotels and other accommodations to choose from. Find out more about Perryville.
What is there to see in Perryville?
Landmarks like National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial might be worth a visit. Natural beauty is on display at Mark Twain National Forest, Mississippi River, and Saint Marys Lake. A couple of additional sights to add to your agenda are Feltz Street Park and Perryville City Hall. Check out what more to see and do in Expedia's Perryville guide.
What's the seasonal weather like in Perryville?
The hottest months are usually July and August with an average temp of 75Ā°F, while the coldest months are January and February with an average of 39Ā°F. Average annual precipitation for Perryville is 48 inches.