Find hotels in Perryville, MO from ¥10,461

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Our top choices for Perryville hotels

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (539)
Modern accommodations near Perryville Country Club featuring an indoor pool for morning swims and a 24-hour fitness center. Enjoy complimentary breakfast, WiFi and parking while exploring nearby Saint Marys Lake. Travelers praise the clean rooms and helpful staff.

"Clean room and pleasant staff"
United States
David
The price is ¥13,528
¥15,487 total
includes taxes & fees
Dec 25 - Dec 26
Holiday Inn Express & Suites Perryville by IHG

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very Good, (937)
This family-friendly Perryville motel features a refreshing indoor pool and 24-hour fitness center. Enjoy free breakfast, WiFi, and parking while staying minutes from Perryville Country Club and Saint Marys Lake. Guests rave about the clean rooms and attentive staff.

"The room was spotless, and the staff was extremely patient. Each one was very helpful. It was easy to get a good night's sleep - the building was very quiet."
United States
Cynthia
The price is ¥9,800
¥11,219 total
includes taxes & fees
Dec 28 - Dec 29
Super 8 by Wyndham Perryville

Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.6 out of 10, (124)
Modern comfort awaits at this Perryville hotel with complimentary breakfast, WiFi, and parking. After a morning swim, explore nearby Saint Marys Lake or practice your swing at the local country club.

"Nice place would recommend Mary Jane’s if you’re looking for good food "
United States
Andrew
The price is ¥10,783
¥12,343 total
includes taxes & fees
Dec 25 - Dec 26
Quality Inn Perryville I-55

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
6.8 out of 10, (415)
Begin your day with complimentary on-the-go breakfast at this welcoming Perryville hotel. Enjoy a refreshing swim in the seasonal outdoor pool after exploring nearby Perryville Country Club and Saint Marys Lake. Free Wi-Fi and parking enhance your stay.

"Was a nice place."
United States
Lesliee
The price is ¥9,138
¥10,461 total
includes taxes & fees
Dec 17 - Dec 18
Days Inn by Wyndham Perryville

Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.2 out of 10, Wonderful, (17)
Located near Feltz Street Park, this aparthotel offers memory foam beds and sofa beds for a comfortable stay. The convenient kitchens and washers/dryers make extended visits easy, while free WiFi and parking add value to your experience.

"Great place to stay! "
United States
Eric
Urban Lofts

Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 star property
Sparta
9.2 out of 10, Wonderful, (369)
Located minutes from Misselhorn Art Gallery, this hotel offers free breakfast and parking. Take a dip in the indoor pool after your workout in the fitness center. The helpful staff receives consistent praise from guests visiting the Sparta Country Club area.

"Spotless"
United States
JAMES
The price is ¥15,394
¥17,083 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express Hotel & Suites Sparta by IHG

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1003)
This quiet retreat offers an indoor pool for morning swims and a relaxing hot tub to end your day. Clean rooms provide a peaceful atmosphere near Litz Park and Lazy L Safari Park, with free breakfast, WiFi, and parking to enhance your stay.

"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is ¥12,904
¥13,643 total
includes taxes & fees
Dec 16 - Dec 17
Drury Inn & Suites Jackson MO

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (512)
Located near Parkview Park and Town Square, this hotel offers a refreshing indoor pool and complimentary hot breakfast each morning. Enjoy the convenience of free WiFi and parking while the attentive staff ensures a pleasant stay for business and leisure travelers alike.

"great property, great breakfast, friendly and knowledgable staff."
United States
Ronald
The price is ¥17,295
¥19,194 total
includes taxes & fees
Dec 18 - Dec 19
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (665)
"Great place "
United States
GUY
The price is ¥13,111
¥14,190 total
includes taxes & fees
Jan 7 - Jan 8, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve
2.5 star property
Ste Genevieve
8.8 out of 10, Excellent, (610)
Tranquil accommodations near the Ste Genevieve Museum Learning Center and Historic District. Enjoy complimentary breakfast, WiFi and parking while business travelers appreciate the helpful staff. Clean rooms provide a serene environment after exploring local attractions.

"Excellent "
United States
James
The price is ¥11,592
¥12,937 total
includes taxes & fees
Dec 21 - Dec 22
Microtel Inn & Suites by Wyndham Sainte Genevieve

Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.6 out of 10, Excellent, (350)
Unwind in this tranquil Chester hotel where quiet rooms offer respite after exploring nearby attractions like Popeye Museum. Free perks include continental breakfast, WiFi, and parking, while the 24-hour fitness center keeps routines on track.

"The room was clean and the staff were friendly. "
United States
RODNEY
The price is ¥11,398
¥12,650 total
includes taxes & fees
Dec 21 - Dec 22
Baymont by Wyndham Chester IL

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (422)
This well-located motel offers complimentary WiFi and self parking, with easy access to Shawnee National Forest and Mississippi River. Near attractions like Litz Park and Lazy L Safari Park, guests praise the helpful 24-hour staff.

"Room was clean and had a refrigerator and microwave for use if needed."
United States
Sherry
The price is ¥10,719
¥11,601 total
includes taxes & fees
Dec 21 - Dec 22
Town House Inn

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (101)
Conveniently located near Shawnee National Forest, this Cape Girardeau hotel offers morning swims in the indoor pool and energizing workouts at the fitness center. Enjoy free breakfast before exploring nearby nature attractions.

"It was a nice stay"
United States
Douglas
The price is ¥13,558
¥15,431 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Tru By Hilton Cape Girardeau

The Conner House B&B

The Conner House B&B
3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (19)
Charming accommodation just a short drive from Fort de Chartes and the Mississippi River. Enjoy a daily full breakfast served between 7:00 AM and 9:30 AM, plus convenient amenities like free WiFi and complimentary self parking.

"Wonderful folks that work there. Nice b&b in a quiet , scenic area."
United States
Bradley
The price is ¥21,866
¥24,267 total
includes taxes & fees
Dec 23 - Dec 24
The Conner House B&B

Triangle Inn Motel

Triangle Inn Motel
2.0 star property
Ste Genevieve
8.0 out of 10, Very Good, (42)
Situated just a short drive from Ste Genevieve's Museum Learning Center and Historic District, this welcoming hotel provides convenient amenities including free WiFi, complimentary parking, and 24-hour front desk service.

"The staff was very accommodating."
United States
Herbert
The price is ¥9,677
¥10,799 total
includes taxes & fees
Dec 14 - Dec 15
Triangle Inn Motel

Briarwood Inn of Sparta

Briarwood Inn of Sparta
2.5 star property
Sparta
7.4 out of 10, Good, (122)
Located near Misselhorn Art Gallery and Sparta Country Club, this motel offers complimentary WiFi and parking. After exploring local hiking paths, guests can return to comfortable rooms while enjoying the peaceful small-town atmosphere.

"My stay was excellent. The owner even gave me a ride to church and I am very thankful"
United States
LaQuana
The price is ¥10,107
¥11,217 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Briarwood Inn of Sparta

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (739)
Modern comfort awaits at this Jackson hotel with an indoor pool and fitness center. Explore nearby Shawnee National Forest or visit Cape Girardeau Conservation Nature Center after enjoying the complimentary breakfast and WiFi.

"Dirty "
United States
Jon
The price is ¥12,434
¥13,456 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites Jackson-Cape Girardeau

Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (297)
Escape to peaceful surroundings at this quiet motel where guests praise the overall property condition. Enjoy a refreshing swim, then explore nearby Arcadia Valley Station. Free WiFi, parking and continental weekend breakfast enhance your restful stay.

"Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again."
United States
Steve
The price is ¥12,120
¥13,239 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Madison Inn Lodge

Sparta Motel

Sparta Motel
2.0 star property
Sparta
4.4 out of 10, (66)
Located near Misselhorn Art Gallery and Sparta Country Club, this welcoming motel offers complimentary WiFi and parking. With 24-hour front desk service, guests enjoy hassle-free access to local attractions.

"Nice hotel, clean, huge pool"
United States
Stacey
The price is ¥10,262
¥11,389 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Sparta Motel
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Stay near popular Perryville attractions

Perryville and related destinations

Historic battlefields and the charming downtown district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Center and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend.

Arched train bridge

Top Perryville Hotel Reviews

More cheap stays in Perryville

Frequently asked questions

What's the best place for a stay in Perryville?
Holiday Inn Express & Suites Perryville by IHG is a favorite with Expedia customers. This hotel offers free breakfast and an indoor pool. Other favorite options based on traveler reviews include Super 8 by Wyndham Perryville and Days Inn by Wyndham Perryville. See all available top hotels, or vacation rentals in Perryville.
What are some of the best vacation rentals in Perryville?
5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING: This vacation home rental near Perryville is located on the waterfront and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and an arcade game room so you can immerse yourself in your vacation. See all vacation rentals in Perryville.
If I need to cancel my hotel reservation in Perryville, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Perryville.
Where can I learn more about changing or cancelling my trip to Perryville?
For additional details about picking new dates or cancelling your trip to Perryville, go to https://www.expedia.com/service/.
What is the top LGBTQ-friendly accommodation in Perryville?
Holiday Inn Express & Suites Perryville by IHG is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. See all available hotels listed as LGBTQ-friendly in Perryville.
What's the best pet-friendly place to stay in Perryville?
Days Inn by Wyndham Perryville is a top hotel for people traveling with their pets, and offers a seasonal outdoor pool and laundry facilities for its human guests. Super 8 by Wyndham Perryville is another good option if you're bringing your pet along. See more pet-friendly hotel accommodations in Perryville.
What's the best hotel to stay close to National Shrine of Our Lady of the Miraculous Medal?
Holiday Inn Express & Suites Perryville, an IHG Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 1.4 mi (2.3 km) from National Shrine of Our Lady of the Miraculous Medal. Other good options within a few miles include Super 8 by Wyndham Perryville and Days Inn by Wyndham Perryville.
What about the best place to stay near Missouri's National Veterans Memorial?
One of the top choices for your stay is Holiday Inn Express & Suites Perryville, an IHG Hotel, located 3.5 mi (5.6 km) from Missouri's National Veterans Memorial, and this hotel offers free breakfast and an indoor pool. Super 8 by Wyndham Perryville and Urban Lofts are a couple of other good options within a few miles.
What are some hotels with pools in Perryville?
Quality Inn Perryville I-55 is a top hotel with a seasonal outdoor pool, free breakfast, and free WiFi. View all hotels with pools in Perryville.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What is staying in Perryville like?
Visitors can enjoy all that Perryville has to offer including the wineries, golf courses, and coffeehouses. Tourists can also enjoy the city's festivals, university setting, and parks. In Perryville, there are 27 hotels and other accommodations to choose from. Find out more about Perryville.
What is there to see in Perryville?
Landmarks like National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial might be worth a visit. Natural beauty is on display at Mark Twain National Forest, Mississippi River, and Saint Marys Lake. A couple of additional sights to add to your agenda are Perryville Country Club and Feltz Street Park. Check out what more to see and do in Expedia's Perryville guide.
What's the seasonal weather like in Perryville?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 39°F. Average annual precipitation for Perryville is 48 inches.