Find hotels in Southeast Missouri, MO from ļæ„9,095
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Our top choices for Southeast Missouri hotels
1. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,000 reviews)
"Nice hotel with evening dinner and buffet breakfast."
Sally
The price is ļæ„18,132
ļæ„20,847 total
includes taxes & fees
Aug 12 - Aug 13
2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (813 reviews)
"Breakfast is good."
Jkara
The price is ļæ„15,136
ļæ„16,381 total
includes taxes & fees
Aug 13 - Aug 14
3. Madison Inn Lodge
Madison Inn LodgeFredericktown
7.6 out of 10, Good, (305 reviews)
"The owner of this place was extremely nice. So was the cleaning staff. I would definitely stay here again."
Christine
The price is ļæ„14,297
ļæ„15,617 total
includes taxes & fees
Aug 11 - Aug 12
4. Perryville RV Resort
Perryville RV ResortPerryville
10.0 out of 10, Exceptional, (2 reviews)
"We had a amazing time it was our 4 yr anniversary"
Von
The price is ļæ„10,848
ļæ„12,419 total
includes taxes & fees
Aug 5 - Aug 6
5. La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
7.8 out of 10, Good, (1,000 reviews)
"Check in and out was very easy. The hotel was clean and the rooms were nice."
Lisa-Marie
The price is ļæ„16,525
ļæ„18,895 total
includes taxes & fees
Aug 12 - Aug 13
6. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (943 reviews)
"I absolutely love staying at Fairfield, that's my go to place. The staff is extremely nice, and amazing, the rooms are clean the bed us comfortable."
Tequilla
The price is ļæ„16,525
ļæ„18,670 total
includes taxes & fees
Aug 16 - Aug 17
7. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent place to stay 3 free drinks during happy and good supper and breakfast. Will stay in a Drury Inn whenever one is available."
Jimmie
The price is ļæ„16,335
ļæ„18,429 total
includes taxes & fees
Aug 23 - Aug 24
8. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
"This was a very clean motel and had an excellent breakfast! Will stay there again!"
Bonnie
The price is ļæ„11,924
ļæ„13,452 total
includes taxes & fees
Aug 17 - Aug 18
9. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Staff and breakfast were excellent."
James
The price is ļæ„15,705
ļæ„17,718 total
includes taxes & fees
Aug 16 - Aug 17
10. Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very Good, (1,002 reviews)
"Great place"
Kellie
The price is ļæ„9,672
ļæ„10,528 total
includes taxes & fees
Aug 17 - Aug 18
11. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,000 reviews)
"This hotel was so clean and comfy! The breakfast was awesome too!"
Jamie
The price is ļæ„13,231
ļæ„13,989 total
includes taxes & fees
Aug 16 - Aug 17
12. Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (910 reviews)
"Great overnight restful stay"
Philip
The price is ļæ„15,272
ļæ„17,101 total
includes taxes & fees
Aug 23 - Aug 24
13. Super 8 by Wyndham Potosi
Super 8 by Wyndham PotosiPotosi
7.2 out of 10, Good, (409 reviews)
"The staff is always very friendly and the rooms are very clean. This is my third time staying there and itās always been a positive stay."
Cathy
The price is ļæ„9,511
ļæ„10,389 total
includes taxes & fees
Aug 13 - Aug 14
14. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (156 reviews)
"The area and room looks great and clean. The service was excellent"
Luis
The price is ļæ„14,602
ļæ„16,620 total
includes taxes & fees
Aug 23 - Aug 24
15. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (212 reviews)
"The staff at breakfast was wonderful!"
Heather
The price is ļæ„15,136
ļæ„17,076 total
includes taxes & fees
Aug 13 - Aug 14
16. The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (588 reviews)
"It was a great stay, very clean, staff was friendly. I wish they offered breakfast."
Mary
The price is ļæ„14,009
ļæ„15,932 total
includes taxes & fees
Aug 28 - Aug 29
17. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (637 reviews)
"Such a great place in fact it was so nice I stayed a few more nights, the casino is amazing"
James
The price is ļæ„16,992
ļæ„19,169 total
includes taxes & fees
Aug 4 - Aug 5
18. Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (658 reviews)
"This is clean well maintained hotel with excellent staff! The breakfast is better than most. Plenty of amenities are nearby!"
Michael
The price is ļæ„19,996
ļæ„21,765 total
includes taxes & fees
Aug 5 - Aug 6
19. Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (609 reviews)
"Breakfast was good nice beds very nice stay"
scott
The price is ļæ„14,484
ļæ„16,582 total
includes taxes & fees
Aug 16 - Aug 17
20. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very Good, (1,008 reviews)
"Good location. Other nearby hotels were questionable, but felt safe in Best Western."
Kevin
The price is ļæ„15,135
ļæ„17,249 total
includes taxes & fees
Aug 23 - Aug 24
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (88 reviews)
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Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouriārestaurants, wineries, and sights from Crane Lake Recreation Area to K Bridge Recreation Area.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Drury Inn & Suites Hayti Caruthersville
10/10 Excellent
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is ļæ„9,672 per night from Aug 17 to Aug 18
ļæ„9,672
ļæ„10,528 total
Aug 17 - Aug 18
includes taxes & fees
Hotels in Southeast Missouri with star-rating
4 Star Hotels
2 properties
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