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Check availability on Southeast Missouri 3 Star Hotels

Tonight
Sep 25 - Sep 26
Tomorrow
Sep 26 - Sep 27
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Southeast Missouri 3-star hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
￥15,825
￥17,853 total
includes taxes & fees
Oct 1 - Oct 2
Drury Plaza Hotel Cape Girardeau Conference Center
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

2. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Scott
￥17,408
￥20,014 total
includes taxes & fees
Sep 27 - Sep 28
Drury Inn & Suites Sikeston, MO
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A hotel room with two beds, a nightstand, a lamp, and a chair.

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Elaine
￥13,318
￥14,414 total
includes taxes & fees
Oct 1 - Oct 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.
A modern lobby with a curved sectional sofa, a glass coffee table, and two armchairs.
A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.

4. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
Nathan
￥13,176
￥14,885 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Poplar Bluff by IHG
A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.
An indoor swimming pool with multiple lanes, surrounded by seating areas and tables.
Two grey armchairs with green cushions, a small side table with a white lamp, and wall-mounted sconces.
A hotel room with a brick wall, two beds, a desk with a TV, and a patterned carpet.

5. Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
Hayti
United States
mike
￥16,142
￥18,397 total
includes taxes & fees
Oct 11 - Oct 12
Drury Inn & Suites Hayti Caruthersville
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
￥16,009
￥18,061 total
includes taxes & fees
Oct 1 - Oct 2
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with a reception desk, seating area, and large windows.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

7. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Dean
￥14,921
￥16,857 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites Poplar Bluff
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.
A restaurant with a brick wall, a flat-screen TV, and a bar area.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

8. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Thomas
￥13,016
￥13,761 total
includes taxes & fees
Oct 11 - Oct 12
Drury Inn & Suites Jackson MO
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A spacious living room with a sofa set, a coffee table, and a dining area.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.
A lobby with seating areas, a reception desk, and a bar.

9. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Kristin
￥19,860
￥22,504 total
includes taxes & fees
Oct 5 - Oct 6
Courtyard by Marriott Cape Girardeau Downtown
A hotel room with two beds, a desk, a chair, a TV, and a large window with a view.
A modern hotel room with a kitchen area, a dining space, and a living area with a view.
A modern hotel room with a large bed, a desk, a TV, and a balcony with a view.
A modern bathroom with a glass shower enclosure, a vanity with a mirror, and a towel rack.

10. Century Casino & Hotel Caruthersville

Century Casino & Hotel Caruthersville
Caruthersville
United States
Sharon
￥19,229
￥21,868 total
includes taxes & fees
Sep 30 - Oct 1
Century Casino & Hotel Caruthersville
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
A corner market with a refrigerated display case and a pantry area.
A reception area with a wooden counter, a coffee machine, and a display of pastries.
A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

11. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Vicki
￥16,058
￥18,141 total
includes taxes & fees
Oct 4 - Oct 5
Fairfield Inn & Suites by Marriott Poplar Bluff
A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.
A hotel room with a large bed, a bedside table with a lamp, a vanity with a mirror, and a wall with framed pictures.
A swimming pool with lounge chairs and a view of the night sky.
A modern hotel with a prominent 'La Quinta' sign, large windows, and a well-lit entrance.

12. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Festus
United States
Lisa-Marie
￥13,359
￥15,277 total
includes taxes & fees
Sep 28 - Sep 29
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

13. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Teresa
￥14,603
￥16,475 total
includes taxes & fees
Oct 4 - Oct 5
Drury Inn & Suites Cape Girardeau
A corridor with a wooden floor, beige walls, and a painting on the left.
A conference room with round tables and chairs, a patterned carpet, and a chandelier.
A breakfast corner with a waffle maker, coffee machines, and a sign for breakfast.
A hotel room with a bathroom, a bed, a desk, and a chair.

14. Baymont by Wyndham Festus

Baymont by Wyndham Festus
Festus
United States
Linda
￥10,573
￥12,089 total
includes taxes & fees
Oct 25 - Oct 26
Baymont by Wyndham Festus
A red wooden mill with a small bridge over a flowing river, surrounded by lush greenery.
A playground with a slide, climbing structures, and a small shelter.
A row of yellow buildings with white railings and a covered front porch.
A dining area with a round table and chairs, large windows with curtains, and a whiteboard on the wall.

15. Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
Mountain View
United States
Joanne
￥15,716
￥17,038 total
includes taxes & fees
Sep 27 - Sep 28
Honeysuckle Inn - Mountain View
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

16. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
￥15,985
￥18,099 total
includes taxes & fees
Oct 4 - Oct 5
Fairfield Inn & Suites by Marriott Sikeston
A bedroom with a bed, a desk, and a chair. There is a window with curtains, a radiator, and a wall-mounted shelf with a towel.
A motel with a parking lot, a covered picnic area, and a row of rooms with individual entrances.
A playground with slides and swings, a mailbox, and a caution sign.
A group of people sitting at picnic tables outdoors, surrounded by trees and a fenced area.

17. Current River Inn

Current River Inn
Van Buren
United States
Misty
￥17,236
￥18,653 total
includes taxes & fees
Oct 1 - Oct 2
Current River Inn
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

18. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Stacy
￥15,827
￥17,920 total
includes taxes & fees
Oct 4 - Oct 5
TownePlace Suites by Marriott Sikeston
A living room with a blue wall, a fireplace, a sofa, and a chair.
A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.
A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.
A bar area with stools and a counter where a bartender is serving drinks.

19. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
￥16,640
￥18,112 total
includes taxes & fees
Oct 4 - Oct 5
EC Reed's Mercantile and Hotel
A bedroom with a bed, bedside table, and wall-mounted light fixtures.
A wooden cabin with a balcony, a small attached room, and a clear sky in the background.
A cozy living room with a sofa, armchairs, a coffee table, and a lamp. There are wall art pieces and a mirror.
A cabin with a porch and steps leading to a deck, situated near a body of water.

20. Johnson's Shut-ins State Park

Johnson's Shut-ins State Park
Middle Brook
United States
Aleksandr
Johnson's Shut-ins State Park
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Southeast Missouri.
The Riverview

The Riverview

777 Main St Cape Girardeau MO
￥16,824
￥18,979 total
Sep 30 - Oct 1
includes taxes & fees
9.4/10 Exceptional! (667 reviews)
The Riverview
Urban Lofts

Urban Lofts

104 North Jackson Street Perryville MO
Get ratesUrban Lofts
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."
Hiram 1-night trip
Posted 2 days ago
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

10/10 Excellent
"Clean room, staff"
Lavonne 2-night trip
Posted 2 days ago
Drury Inn & Suites Poplar Bluff

Frequently asked questions

What are the best 3-star hotels in Southeast Missouri?
If you're staying in Cape Girardeau for your Southeast Missouri vacation, you'll find some cozy 3-star hotels. Many Expedia travelers book Courtyard by Marriott Cape Girardeau Downtown. Around 0.64 kilometers west of the downtown area, it features a terrace and a cafe. Another highly rated escape is Drury Plaza Hotel Cape Girardeau Conference Center. Book a room here and enjoy access to a swimming pool and high-speed internet services, and be approximately 8 kilometers west of the center.
How much does it cost to stay in a 3-star hotel in Southeast Missouri?
Use Expedia's sort and search filters to land an affordable 3-star hotel for your Southeast Missouri break. Just set your maximum rate with our pricing tool. You can also pick your amenities, preferred neighborhood and lots more.
  • Search for the lowest price per night right now from ￥18,979
What is the difference between a 4-star and 3-star hotel in Southeast Missouri?
Relaxation is effortless in 3-star hotels in Southeast Missouri. In addition to pleasant surroundings, these more affordable stays come with a wealth of amenities like WiFi, coffee maker and on-site gym. A 4-star hotel offers a more sophisticated experience with upscale features such as an on-site spa center, outdoor or indoor pool and more spacious rooms. Regardless of your desired hotel category or budget, we have the ideal match for you.

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