Default HTG hotel image

Matthews Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for Matthews vacation rentals

A single-story house with a gabled roof, a front porch with two chairs, and a front door with a decorative glass panel.

1. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
The price is ￥31,512
￥53,362 total
includes taxes & fees
Nov 4 - Nov 5
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
A covered outdoor seating area with stone flooring and chairs, a stone pathway, and a wooden structure.

2. Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.
Union City
10.0 out of 10, Exceptional, (9 reviews)
"The home was spotless, very comfortable and a great location for what we needed."
United States
Sherrie S.
The price is ￥15,756
￥24,294 total
includes taxes & fees
Nov 5 - Nov 6
Vacation rental attached to our house out in the country.
A modern kitchen with stainless steel appliances, wooden cabinets, and a white countertop.

3. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Dexter
10.0 out of 10, Exceptional, (4 reviews)
"Perfect place for our stay on the way to North Carolina! Clean, cozy and convenient!"
United States
Robert G.
The price is ￥22,168
￥25,899 total
includes taxes & fees
Nov 4 - Nov 5
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
A wooden interior with a herringbone floor, a sliding barn door, a wooden door with a glass panel, and a window with blinds.

4. Tiny house on the lake with tv free internet walk shower

Tiny house on the lake with tv free internet walk shower
Tiptonville
10.0 out of 10, Exceptional, (1 review)
"Dave was very accommodating and the home was clean."
United States
Katherine P.
The price is ￥28,361
￥46,386 total
includes taxes & fees
Nov 4 - Nov 5
Tiny house on the lake with tv free internet walk shower
A two-story house with a front porch, a covered entryway, and a small garden with white flowers.

5. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
7.8 out of 10, Good, (39 reviews)
"Overall, it was a good experience. I would stay again."
United States
Tammy G.
The price is ￥16,910
￥32,489 total
includes taxes & fees
Nov 8 - Nov 9
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Matthews Hotel Reviews

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"It was affordable and coean"
William 3-night trip
Posted 2 days ago
Super 8 by Wyndham Sikeston/Miner Area

Find out more about Matthews

Search for holiday rentals in Matthews on Expedia! You can easily find your home rentals, villas, holiday apartments in Matthews using one of the methods below:

  • View our selection of featured holiday rentals in Matthews
  • Use the map to find apartments and other holiday homes in the Matthews neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Matthews while they last

Look no further and take a look at our great range of rental properties in Matthews!

Frequently asked questions

Are there vacation rentals in Matthews?

Yes, we offer vacation rentals near the most popular local attractions in Matthews, or you can choose a secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Matthews has to offer?

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This vacation home rental near Matthews offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games.

What’s there to see and do in Matthews?

While you're exploring the area, Big Oak Tree State Park and Central Park are a couple of picturesque spots to get outside and enjoy nature. Marston Community Center and Sikeston Depot Museum are a couple of places you'll find in the larger area.

What’s a vacation rental in Matthews like?

Vacation rentals are privately owned properties you can book for a few weeks or just a few days in Matthews. Vacation rentals feature amenities such as laundry facilities and kitchens so you'll have all the conveniences of home. If you're concerned about a clean environment, vacation rentals can offer a sense of security away from shared hotel elevators and lobbies packed with people while still allowing you to travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for families.