Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers comfort in a rural setting with free breakfast and an indoor pool. Relax at the onsite spa and sun loungers by the pool. Dry cleaning, laundry services, and luggage storage are available, with highly praised staff.
Located in Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is in a rural area and near the airport. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also worth visiting. Visit our Cape Girardeau travel guide
63701, MO, Cape Girardeau, 3253 William Street
What's nearby
Southeast Missouri State University
6 min drive - 6.3 km
Saint Francis Medical Center
6 min walk - 0.6 km
Riverfront Park
6 min drive - 7.7 km
Century Casino & Hotel Cape Girardeau
8 min drive - 9.4 km
Show Me Center
9 min drive - 9.1 km
Getting around
Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
10 min drive
Restaurants
Chick-fil-A
7 min walk
Rhodes
20 min walk
McDonald's
10 min walk
White Castle
10 min walk
Wings Etc.
9 min walk
About this property
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hotel near Shawnee National Forest
You can look forward to free breakfast, dry cleaning/laundry services, and a gym at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG. Take some time to relax at the onsite spa. In addition to a business center, guests can connect to free in-room WiFi.
You'll also enjoy perks such as:
Swimming pool along with sun loungers
Free self parking
An indoor pool, a banquet hall, and laundry services
Luggage storage, smoke-free premises, and 1 meeting room
Guest reviews speak highly of the breakfast and helpful staff
Room features
All 102 rooms feature comforts such as premium bedding and pillow menus, in addition to thoughtful touches like laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the clean rooms at the property.
More amenities include:
Pillowtop mattresses and down comforters
Bathrooms with free toiletries and hair dryers
52-inch flat-screen TVs with premium channels
Separate sitting areas, mini fridges, and microwaves
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Available in all rooms: Free WiFi and wired internet
Available in some public areas: Free WiFi and wired internet
Parking and transportation
Free self parking on site
Wheelchair-accessible parking available
Food and drink
Free breakfast available
Things to do
Full-service spa
Gym
Indoor pool
Family friendly
In-room microwave
Indoor pool
Laundry facilities
Mini-fridge
Conveniences
24-hour front desk
Free newspapers in lobby
Laundry facilities
Luggage storage
Safe at front desk
Vending machine
Guest services
Dry cleaning/laundry service
Housekeeping (daily)
Porter/bellhop
Business services
118 square feet of conference space
Business center
Meeting room
Outdoors
Pool loungers
Accessibility
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Assistive listening devices
Braille/raised signage
Visual fire alarm
Well-lit path to entrance
Wheelchair accessible (may have limitations)
Wheelchair-accessible parking
Wheelchair-accessible path of travel
Wheelchair-accessible path to elevator
More
1 building
4 floors
Banquet hall
Smoking not allowed
Room amenities
Bedroom
Down comforter
Pillow menu
Pillowtop mattress
Premium bedding
Bathroom
Free toiletries
Hair dryer
Private bathroom
Shampoo
Soap
Toilet paper
Towels provided
Entertainment
52-inch flat-screen TV with premium cable channels
Food and drink
Coffee/tea maker
Microwave
Mini-fridge
More
Air conditioning (climate-controlled)
Connecting rooms available
Desk
Free local calls
Iron/ironing board
Laptop workspace
Phone
Safe
Separate sitting area
Policies
Check-in
Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21
Check-out
Check-out before 11 AM
Contactless check-out available
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets not allowed
Children and extra beds
Children are welcome
Cribs (infant beds) are not available
Property payment types
Important information
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
We should mention
Pool access available from 8 AM to 11 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Property is also known as
Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG
Frequently asked questions
Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?
Yes, this property has an indoor pool. Pool access is from 8 AM–11 PM.
How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?
As of Mar 18, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Mar 29, 2026 start from ¥15,738, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG pet-friendly?
No, pets are not allowed at this property.
How much is parking?
Self parking is free at this property.
What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?
Check-in start time: 3:00 PM; Check-in end time: anytime.
What time is check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?
Check-out is at 11 AM.
Where is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG located?
Situated near the airport, this spa hotel is 0.6 mi (1 km) from Saint Francis Medical Center and within 3 mi (5 km) of Saint Francis Healthcare System and Southeast Missouri Hospital. Cape Splash Family Aquatic Center is 3 mi (4.9 km) away.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
Very clean rooms, no unwanted unlocks of doors while you are in your room. The guest serves were delightful and very happy to help. Breakfast was nice and consistently restocked. Only reason for four and half stars, the very first attendant was a little rude. I only saw her the night of check in. Also the pancake maker wouldn’t work, I do craved pancakes and couldn’t get any. But other than that it was a great stay!!!
We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly.
Fast, very friendly desk service. We were allowed to check in a little early, a big plus since we arrived at 2 for a wedding at 3!! We got down for breakfast 30 minutes before the end of closing and it was evident. But the pancakes were great! Thanks for everyone's service!
Our stay was wonderful. The rooms are so nice. Bed was comfortable. The jaccuzi tub is excellent. The free breakfast was lovely. Even had healthy options with turkey sausage and egg white omelets. Delicious.