Cape Girardeau Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ￥45,448 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Find the Best Cape Girardeau Vacation Packages
Cape Girardeau Hotel Deals
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is ￥13,996 per night from Dec 2 to Dec 3
￥13,996
￥15,788 total
Dec 2 - Dec 3
includes taxes & fees
9.4/10 Exceptional! (1,005 reviews)
Yes
Reviewed on Nov 15, 2025
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is ￥10,886 per night from Nov 23 to Nov 24
￥10,886
￥12,281 total
Nov 23 - Nov 24
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Everything!
Reviewed on Nov 9, 2025
The Riverview
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is ￥14,380 per night from Nov 23 to Nov 24
￥14,380
￥16,223 total
Nov 23 - Nov 24
includes taxes & fees
9.4/10 Exceptional! (456 reviews)
Great room, close to downtown, awesome food options in the venue as well. Really nice views of the river.
Reviewed on Nov 19, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Cape Girardeau
Southeast Missouri State University
4.5/5(76 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Other vacations you might like
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
